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    v1.0.28
    OpenPayerBilling CodesAdministrative, Miscellaneous and InvestigationalHCPCS hcpcs-a9560-technetium-tc-99m-labeled-rbc-diagnostic-up-to-30-mCi
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    HCPCS Level II A9560: Technetium Tc-99m Labeled Red Blood Cells, Diagnostic

    HCPCS Level II code A9560 describes a diagnostic radiopharmaceutical service using technetium Tc-99m labeled red blood cells, billed per study dose up to 30 millicuries; typical service type is a nuclear medicine diagnostic blood pool study and the typical site of service is an outpatient imaging or nuclear medicine department where radiotracer preparation and imaging are performed.

    For related coverage guidance, see recent payer policy updates: Interferential Stimulation Devices (for home use), Durable Medical Equipment (DME): Tumor Treating Fields (Alternating Electric Field Therapy) Medical Guideline, Durable Medical Equipment (DME): Bone Growth Stimulators Medical Guideline.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult referred to nuclear medicine for evaluation of suspected gastrointestinal bleeding or occult blood loss when endoscopy is non-diagnostic or intermittent bleeding is suspected. The referring clinician documents signs such as melena, hematochezia, positive fecal occult blood testing or dropping hemoglobin/hematocrit without clear source. The nuclear medicine team performs a technetium Tc-99m labeled red blood cell (RBC) blood-pool study using A9560 to prepare and dose autologous RBCs (up to 30 millicuries per study dose). The workflow includes: pre-procedure verification of indication and informed consent, phlebotomy to obtain and label the patient’s blood sample, in vitro or in vivo labeling of RBCs with Tc-99m per local protocol, intravenous reinjection of labeled RBCs, dynamic and delayed planar and/or SPECT imaging to localize active bleeding, and post-procedure monitoring. Image interpretation is performed by a radiologist or nuclear medicine physician and reported to the referring clinician for next-step management. Typical sites of service are outpatient hospital-based nuclear medicine departments, hospital inpatient radiology/nuclear medicine suites, and freestanding imaging centers equipped for radiopharmaceutical handling and blood handling under appropriate regulatory controls.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    78226Liver/spleen and blood pool imaging; static and/or blood-pool imagingOften performed alongside or as part of radionuclide blood-pool studies when evaluating hepatic/splenic sequestration or vascular anomalies.
    78227Imaging for gastrointestinal bleeding, blood-pool or tagged red blood cell study, limited or single-photon imagingDirectly related; represents the imaging procedure using tagged RBCs to localize GI bleeding and is commonly billed in conjunction with the radiopharmaceutical supply code A9560.
    78228Imaging for gastrointestinal bleeding, blood-pool or tagged red blood cell study, planar and SPECT/ SPECT-CT imagingUsed when advanced tomographic imaging (SPECT or SPECT/CT) is performed in addition to planar imaging for localization and surgical planning.
    99070Supplies and materials (except for those normally included with the office visit)May be used to report non-routine disposable supplies used in blood handling if payor policy allows; however, institutional billing practices vary.
    36415Collection of venous blood by venipuncturePerformed to obtain the autologous blood sample for labeling prior to preparation of the Tc-99m RBC radiopharmaceutical.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    364SR0400XRehabilitation Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
    163WG0600XGerontology Registered NurseNursing Service Providers · Registered Nurse
    163WW0000XWound Care Registered NurseNursing Service Providers · Registered Nurse
    3336L0003XLong Term Care PharmacyA pharmacy that dispenses medicinal preparations delivered to patients residing within an intermediate or skilled nursing facility, including intermed…
    163WE0003XEmergency Registered NurseNursing Service Providers · Registered Nurse

    Related Payer Policy Updates

    Specialty: Durable Medical Equipment (DME)1 / 3

    5 rows

    PolicyPayerEffective Date
    Interferential Stimulation Devices (for home use)Moda Health2026-10-01
    Durable Medical Equipment (DME): Tumor Treating Fields (Alternating Electric Field Therapy) Medical GuidelineWPS Health Insurance2026-10-01
    Durable Medical Equipment (DME): Bone Growth Stimulators Medical GuidelineWPS Health Insurance2026-10-01
    General Durable Medical Equipment (DME) Medical GuidelineWPS Health Insurance2026-10-01
    Prior Authorization for Durable Medical Equipment (DME)Blue Cross Blue Shield - Rhode Island2026-10-01

    Related Codes

    HCPCS-A9150-NON-PRESCRIPTION-DRUGS

    HCPCS Level II A9150: Non-prescription Drugs

    HCPCS-A9152-SINGLE-ORAL-VITAMIN-MINERAL-DOSE

    HCPCS A9152: Single Oral Vitamin/Mineral/Trace Element

    HCPCS-A9153-MULTIVITAMIN-ORAL-PER-DOSE

    HCPCS A9153: Multiple Vitamins, Oral, Per Dose

    HCPCS-A9154-ARTIFICIAL-SALIVA-1ML

    HCPCS Level II A9154: Artificial saliva, 1 ml

    HCPCS-A9155-ARTIFICIAL-SALIVA-30ML

    HCPCS Level II A9155: Artificial Saliva, 30 mL

    HCPCS-A9156-ORAL-MUCOADHESIVE-PER-1ML

    HCPCS Level II A9156: Oral Mucoadhesive, Per 1 ml

    HCPCS-A9180-PEDICULOSIS-TOPICAL-TREATMENT-PATIENT-ADMINISTRATION

    HCPCS Level II A9180: Pediculosis Topical Treatment for Patient/Caretaker

    HCPCS-A9268-PROGRAMMER-TRANSIENT-INGESTED-CAPSULE

    HCPCS Level II A9268: Programmer for Transient Orally Ingested Capsule

    HCPCS-A9269-PROGRAMMABLE-TRANSIENT-ORAL-CAPSULE

    HCPCS Level II A9269: Programmable Orally Ingested Capsule, Per Month

    HCPCS-A9270-NON-COVERED-ITEM-OR-SERVICE

    HCPCS A9270: Non-covered Item or Service

    Showing 1–10 of 138

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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