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    v1.0.28
    OpenPayerBilling CodesMedical And Surgical SuppliesHCPCS hcpcs-a4385-ostomy-skin-barrier-4x4-extended-wear
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    HCPCS A4385: Ostomy Skin Barrier, Solid 4x4, Extended Wear

    HCPCS Level II code A4385 describes an ostomy skin barrier, solid 4 x 4 (or equivalent), extended wear design without built-in convexity, supplied as a single device; this item is used as an ostomy pouching system component (supply) for patients with stomas and is typically provided in an outpatient, home care, or durable medical equipment setting where ostomy supplies are furnished.

    For related coverage guidance, see recent payer policy updates: Salivary Hormone Testing, Bone Turnover Markers Testing, Parathyroid Hormone, Phosphorus, Calcium, and Magnesium Testing.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult or elderly ostomy recipient (colostomy, ileostomy, or urostomy) who requires a replacement ostomy skin barrier. The device described by A4385 is a solid, extended-wear skin barrier sized approximately 4 x 4 cm (or equivalent) without built-in convexity. The scenario commonly occurs in outpatient wound/ostomy clinics, home health visits, long-term care facilities, or during durable medical equipment (DME) dispensing appointments.

    The clinical workflow begins with assessment by an enterostomal therapy nurse or wound care clinician who documents stoma type, peristomal skin condition, frequency of appliance changes, and supply needs. The clinician measures the stoma and selects a flat (non-convex), extended-wear barrier when the stoma is flush with or slightly above skin level and there is no need for contouring pressure. The clinician records the medical necessity (e.g., protection of peristomal skin from effluent, management of mild peristomal irritation) and prescribes the quantity and frequency. The prescription is submitted to the durable medical equipment supplier and to the patient’s insurer for coverage determination. The supplier dispenses individual barriers coded as A4385 and documents manufacturer, size, and lot numbers in the patient record. Follow-up includes monitoring for leakage, skin breakdown, and need for alternative barrier types (e.g., convex or cut-to-fit).

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    97597Debridement (eg, high-pressure waterjet, sharp) open wound, first 20 sq cm or lessPerformed prior to appliance application if necrotic tissue or adherent residue requires debridement to promote adhesion and healthy peristomal skin.
    97606Application of negative pressure wound therapy (once per 7 days)May be used for significant peristomal wounds prior to or in conjunction with ostomy management; not routine for intact stoma.
    99406Smoking and tobacco use cessation counseling, intermediate, 3-10 minutesBehavioral counseling sometimes billed by clinicians during ostomy education visits; included if counseling meets payer criteria.
    99213Office or other outpatient visit for the evaluation and management of an established patient, low to moderate complexityTypical office visit code for ostomy assessment, supply prescription, and patient education.
    A9270Non-covered item or service (not otherwise classified)Sometimes used by suppliers when a specific off-list ostomy accessory is provided; inclusion for reference only.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    332B00000XDurable Medical Equipment & Medical SuppliesA supplier of medical equipment such as respirators, wheelchairs, home dialysis systems, or monitoring systems, that are prescribed by a physician for…
    207RH0003XHematology & Oncology PhysicianAn internist doctor of osteopathy that specializes in the treatment of the combination of hematology and oncology disorders. A doctor of osteopathy t…
    286500000XMilitary HospitalA health care facility operated by the Department of Defense.
    207ZN0500XNeuropathology PhysicianA neuropathologist is expert in the diagnosis of diseases of the nervous system and skeletal muscles and functions as a consultant primarily to neurol…
    284300000XSpecial HospitalA designation by the AHA of a hospital whose primary function of the institution is to provide diagnostic and treatment services for patients who have…
    163WS0121XPlastic Surgery Registered NurseNursing Service Providers · Registered Nurse
    3336H0001XHome Infusion Therapy PharmacyPharmacy-based, decentralized patient care organization with expertise in USP 797-compliant sterile drug compounding that provides care to patients wi…

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    5 rows

    PolicyPayerEffective Date
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01
    Parathyroid Hormone, Phosphorus, Calcium, and Magnesium TestingOscar Health2026-10-01
    Testosterone — Coverage Criteria for Measurement and MonitoringOscar Health2026-10-01
    Thyroid Disease TestingOscar Health2026-10-01

    Related Codes

    HCPCS-A4206-STERILE-SYRINGE-1CC-NEEDLE

    HCPCS A4206: Syringe with Needle, 1 cc or Less, Sterile

    HCPCS-A4207-STERILE-2CC-SYRINGE-WITH-NEEDLE

    HCPCS Level II A4207: Syringe with Needle, Sterile 2 cc

    HCPCS-A4208-STERILE-3CC-SYRINGE-WITH-NEEDLE

    HCPCS Level II A4208: Syringe with Needle, Sterile 3 cc

    HCPCS-A4209-STERILE-SYRINGE-WITH-NEEDLE-5CC-OR-GREATER

    HCPCS Level II A4209: Syringe with Needle, Sterile 5 cc or Greater

    HCPCS-A4210-NEEDLE-FREE-INJECTION-DEVICE

    HCPCS Level II A4210: Needle-free Injection Device, Each

    HCPCS-A4211-SUPPLIES-SELF-ADMINISTERED-INJECTIONS

    HCPCS Level II A4211: Supplies for Self-Administered Injections

    HCPCS-A4212-NON-CORING-NEEDLE-STYLET-CATHETER-ACCESS-SUPPLY

    HCPCS Level II A4212: Non-coring Needle or Stylet with/without Catheter

    HCPCS-A4213-STERILE-SYRINGE-20CC-OR-GREATER

    HCPCS Level II A4213: Syringe, Sterile, 20 cc or Greater, Each

    HCPCS-A4215-STERILE-NEEDLE-SINGLE-EACH

    HCPCS Level II A4215: Needle, Sterile, Any Size

    HCPCS-A4216-STERILE-DILUENT-FLUSH-10ML

    HCPCS Level II A4216: Sterile Diluent/Flush, 10 ml

    Showing 1–10 of 633

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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