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    v1.0.30
    OpenPayerBilling CodesMedication Therapy Management ServicesCPT cpt-99606-pharmacist-medication-evaluation-15-minute-established-patient
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    CPT 99606: Pharmacist Medication Evaluation, Established Patient, 15 Min

    CPT code 99606 describes a pharmacist-provided, patient-specific medication evaluation for an established patient, delivered in person during a dedicated 15-minute encounter that reviews the patient’s history and medication list to assess therapy effectiveness, adherence, interactions, and the need for adjustments; service type is a pharmacist medication therapy management/medication evaluation and the typical site of service is an outpatient clinic, community pharmacy consultation area, or similar ambulatory setting.

    For related coverage guidance, see recent payer policy updates: Diabetic Supplies, Radiofrequency Ablation for Thyroid Nodules, Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old established patient with multiple chronic conditions (type 2 diabetes mellitus, hypertension, and chronic heart failure) presents to an outpatient clinic pharmacy or ambulatory care clinic for a scheduled medication therapy management visit. The pharmacist performs a focused, face-to-face, 15-minute, patient-specific medication evaluation including review of the patient’s medical history, current medication list (prescription, OTC, and supplements), adherence barriers, recent lab values (e.g., HbA1c, renal function), and assessment for adverse drug events or drug–drug interactions. The visit includes counseling on medication use, identification of therapy optimization opportunities, and documentation of findings and recommendations in the medical record. Typical workflow: referral from primary care or chronic care management team → pre-visit chart review by pharmacist → in-person 15-minute medication evaluation using CPT 99606 → documentation and communication of recommendations to the ordering clinician and care team. Typical site of service: outpatient clinic, ambulatory care pharmacy within a medical practice, or a federally qualified health center where pharmacists provide direct patient care.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99605Medication therapy management, initial 15 minutes, face-to-face with a new patientUsed for the initial MTM visit for a new patient; CPT 99606 is for established patients, while 99605 is for new patients
    99607Each additional 15 minutes (list separately in addition to codes for primary service)Used when the medication evaluation requires more than the initial 15 minutes and additional time is billed in 15-minute increments after 99606
    99490Chronic care management services, at least 20 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar monthMay be billed by the practice alongside pharmacist interventions as part of a broader chronic care management program when time thresholds are met
    99487Complex chronic care management services, first 60 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar monthRelevant when the patient requires more complex medication management integrated into CCM workflows
    99213Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutesMay be performed by the physician on the same day for a separate, identifiable E/M visit; 25 modifier can be applicable if billed on the same day as 99606

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    93Modifier 93 denotes that a billed service was delivered synchronously via audio-only telecommunications (real-time telephone or other audio-only system). The AMA added modifier 93 in CPT Appendix A…- When to use: Apply modifier -93 when a synchronous, real-time, two-way patient–provider encounter is conducted entirely via audio-only (telephone or other real-time interactive audio-only…
    95Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Q00000X
    207L00000X
    333600000X
    2080P0216X
    207ZI0100X
    2279P3900X
    225XF0002X
    2279P3800X

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    10 rows

    PolicyPayerEffective Date
    Diabetic SuppliesCigna2026-10-15
    Radiofrequency Ablation for Thyroid NodulesCigna2026-10-15
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only)UnitedHealthcare2026-10-01
    Tzield (teplizumab-mzwv) CoverageUnitedHealthcare2026-10-01
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Indiana Only)UnitedHealthcare2026-10-01
    Medical Necessity Guidelines Insulin PumpsMass General Brigham Health Plan2026-10-01
    Medical Necessity Guidelines: Continuous Glucose MonitorsMass General Brigham Health Plan2026-10-01
    Continuous Glucose MonitoringAmbetter Nevada2026-10-01
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01

    Related Codes

    CPT-99605-PHARMACIST-MEDICATION-EVALUATION-NEW-PATIENT-15MIN

    CPT 99605: Pharmacist 15-Minute In-Person Medication Evaluation, New Patient

    CPT-99607-PHARMACIST-MEDICATION-EVALUATION-ADDITIONAL-15-MIN

    CPT 99607: Additional 15-Minute In-Person Medication Evaluation

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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