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    v1.0.30
    OpenPayerBilling CodesDigitally Stored Data Services/Remote Physiologic MonitoringCPT cpt-99453-remote-physiologic-monitoring-setup-education
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    CPT 99453: Remote Physiologic Monitoring Equipment Setup and Education

    Medicare pays $23 on average nationally for this procedure.

    CPT code 99453 describes the provider setup of remote physiologic monitoring equipment and patient education on device use, a remote physiologic monitoring service typically performed as an ambulatory or clinic-based telehealth support activity to enable ongoing home-based physiologic data collection and monitoring.

    For related coverage guidance, see recent payer policy updates: Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood Pressure, Cardiology - Ivabradine, Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA).

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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old patient with a history of hypertension and congestive heart failure is prescribed a home remote physiologic monitoring (RPM) program to track vital signs and weight daily. The clinical workflow begins when the clinician orders RPM; the practice or durable medical equipment (DME) team receives the order, provisions the RPM device (for example, a blood pressure cuff, weight scale, or pulse oximeter), and schedules a set-up and education visit. During the setup encounter, a qualified provider or trained clinical staff performs device configuration, pairs the device to the patient’s phone or gateway, verifies connectivity, demonstrates proper measurement technique, and documents patient understanding. The encounter includes collection of baseline measurements and confirmation of the patient’s ability to transmit data. Education covers when and how often to use the device, troubleshooting, and escalation instructions if readings are abnormal. The service is reported with 99453 for the initial equipment setup and patient education; subsequent remote data collection and management are reported with separate RPM codes as clinically appropriate. Typical sites of service are outpatient clinics, ambulatory care centers, or the patient’s home when the provider or staff conducts an in-home setup visit. Common payors include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, BUCA, and Medicare, each following their RPM coverage policies for eligibility and documentation requirements.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99454Device(s) supply with daily recordings or programmed alert transmission, each 30 daysReported for the monthly supply and transmission of data from RPM devices after initial setup by 99453.
    99457Remote physiologic monitoring treatment management services, first 20 minutes of clinical staff/physician/other qualified healthcare professional time in a calendar month requiring interactive communication with the patient/caregiverUsed for the first 20 minutes per month of RPM clinical management after data collection begins; follows 99453 initial setup.
    99458Remote physiologic monitoring treatment management services, each additional 20 minutesUsed to report additional time beyond 99457 for RPM clinical management in the same month.
    99091Collection and interpretation of physiologic data digitally stored and/or transmitted by the patient to the physician or other qualified health care professional, requiring a minimum of 30 minutes of timeAlternative or supplementary code for collection and interpretation of patient-generated physiologic data; may be used in workflows with intensive data review following 99453 setup.
    A9279Continuous glucose monitor supplies (not otherwise classified) — HCPCS II code example for device suppliesRepresents possible device supply coding in DME or HCPCS when specific device supplies accompany RPM services after the 99453 setup.

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    95Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208D00000X
    208M00000X
    363L00000X
    207K00000X
    3336C0002X
    2279P3800X
    364SG0600X
    320700000X

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood PressureBluecross Idaho2026-11-01
    Cardiology - IvabradineCigna2026-10-15
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Percutaneous Ventricular Assist DeviceUnitedHealthcare2026-10-01
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Left Atrial Appendage Closure Devicesexcellus_health_plan_inc2026-09-17
    Left Atrial Appendage Closure Devicesuniverahealthcare2026-09-17
    Cardiac Omnibus CodesCigna2026-09-15

    Related Codes

    CPT-99091-REMOTE-PHYSIOLOGIC-DATA-INTERPRETATION

    CPT 99091: Interpretation of Patient-Provided Digital Health Data, 30 Minutes

    CPT-99445-REMOTE-PHYSIOLOGIC-MONITORING-DEVICE-SUPPLY-2-15-DAYS

    CPT 99445: Supply of Devices for Short-Term Remote Physiologic Monitoring

    CPT-99454-REMOTE-PHYSIOLOGIC-MONITORING-DEVICE-SUPPLY-16-30-DAYS

    CPT 99454: Remote Physiologic Monitoring Device Supply, 16–30 Days

    CPT-99473-BP-DEVICE-CALIBRATION-PATIENT-TRAINING

    CPT 99473: Blood Pressure Device Calibration and Patient Training

    CPT-99474-HOME-BLOOD-PRESSURE-MONITORING-REMOTE-PATIENT-MONITORING

    CPT 99474: Home Blood Pressure Monitoring with 30-Day Average Report

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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