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CPT 96440: Intracavitary Chemotherapy Administration to Pleural Space
CPT code 96440 represents intracavitary chemotherapy administered into the pleural cavity with thoracentesis and chest-tube drainage. This procedure is used when anticancer agents are delivered directly into the pleural space to manage malignant pleural effusions or to target pleural-based malignancy. Nationally, accurate coding for intracavitary chemotherapy is important for clinical documentation, service-level classification, and consistent reimbursement across hospital settings.
Key payers in the scope of this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context, typical sites of service, and operational considerations. The publication presents benchmarks and payment-related observations, highlights coding and documentation implications for hospital-based care, and summarizes relevant policy updates affecting how this service is billed and authorized. The content is intended for coding professionals, revenue cycle staff, and clinical managers seeking a clear reference for CPT code 96440 and its role in delivering intracavitary pleural chemotherapy.
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Billing Code Overview
CPT code 96440 describes administration of a chemotherapy agent directly into the pleural cavity. The procedure includes thoracentesis and insertion of a chest tube to access and drain the pleural space before instillation of the chemotherapeutic agent.
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Service type: Intracavitary chemotherapy administration via thoracostomy and pleural drainage
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Typical site of service: Hospital inpatient or hospital outpatient setting where thoracostomy and pleural drainage can be performed under appropriate monitoring