Summary & Overview
CPT 95147: Preparation of Three Single Stinging Insect Venom Extracts
CPT code 95147 covers the mixing and preparation of a specified number of doses of extract of three single stinging insect venoms. This procedural code is used in allergen immunotherapy services where multiple venom extracts are combined and prepared for patient administration. Nationally, accurate use of this code affects billing for allergy clinics, outpatient practices, and entities managing immunotherapy services, with implications for coding compliance and revenue cycle capture.
Key payers addressed in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find benchmarks for typical use, guidance on common billing modifiers and documentation touchpoints, and clinical context about when mixed venom extracts are prepared. The publication also outlines coding relationships and common payer considerations for coverage and reimbursement processes. Intended for billing staff, compliance officers, and clinicians involved in allergen immunotherapy, the summary provides a concise reference to understand CPT code 95147 and its role in venomspecific extract preparation.
Billing Code Overview
CPT code 95147 describes the mixing and preparation of a specified number of doses of extract of three single stinging insect venoms. This service is typically provided as part of allergen immunotherapy preparation and is classified as a procedural service for the handling and compounding of multiple venom extracts.
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Service type: Allergen immunotherapy preparation (mixing and preparing venom extracts)
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Typical site of service: Allergy clinic, outpatient clinic, or other ambulatory care setting where allergen immunotherapy is prepared and administered
Clinical & Coding Specifications
Clinical Context
A typical patient is an adult or pediatric patient with a history of systemic allergic reactions to stinging insects (bee, wasp, hornet) who undergoes venom immunotherapy. The patient presents to an outpatient allergy clinic or ambulatory infusion/preparation area for initiation or continuation of maintenance venom immunotherapy. The clinical workflow begins with the allergist or trained clinic nurse confirming the specific three single stinging insect venoms required (for example, honeybee, yellow jacket, and hornet), reviewing the patient’s prior dosing, lot numbers, and expiration dates, and adhering to sterile technique. The provider mixes and prepares the specified number of extract doses for that visit according to the prescribed concentration and schedule, labels syringes or vials with patient identifiers, dose, concentration, lot number, and administration date, and documents preparation in the medical record. Prepared doses are then transported to the treatment area where the patient receives subcutaneous injections under observation for potential systemic reactions. Typical sites of service are outpatient allergy clinics, ambulatory surgical centers when concurrent procedures occur, or hospital outpatient departments when medically indicated; the preparation task itself is performed in a clinical pharmacy or procedure preparation room within these settings.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier — standard reporting | Use when no special circumstances apply. |