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    v1.0.30
    OpenPayerBilling CodesOther Ophthalmological Services or ProceduresCPT cpt-92499-unlisted-ophthalmological-procedure
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    CPT 92499: Ophthalmological Procedure, Unlisted

    CPT code 92499 is an unlisted ophthalmological procedure code used to report ophthalmology services that do not have a specific CPT code; it is intended for miscellaneous diagnostic or therapeutic ocular procedures performed in an ophthalmology or eye clinic setting and typically represents specialty-level ophthalmic procedures delivered in an outpatient clinic or ambulatory surgery center.

    For related coverage guidance, see recent payer policy updates: Corneal Remodeling for Refractive Errors and Corneal Grafting and Transplantation, Glaucoma Agents iDose TR (travoprost intracameral implant), Topical Treatments for Dry Eye Disease.

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    Clinical & Coding Specifications

    Clinical Context

    A patient presents to an ophthalmology clinic for an eye procedure that does not have a specific CPT code and therefore is billed with 92499. Typical scenarios include a novel or uncommon diagnostic or therapeutic ophthalmic intervention such as an experimental imaging technique, a custom-fit ocular prosthesis adjustment, an atypical anterior segment irrigation/medication delivery that is not described by existing codes, or a unique service provided during a clinical trial. The clinical workflow begins with evaluation by an ophthalmologist or optometrist, documentation of the indication and informed consent, performance of the atypical procedure in a procedure room or ambulatory surgery center, and documentation of the technique, time, and any devices used. Billing staff append the appropriate modifier(s) to 92499 to indicate professional vs technical components, laterality, unusual circumstances, or payer-required attestations. Typical sites of service include the ophthalmology office procedure room, ambulatory surgery center, or hospital outpatient department. Payers commonly involved in adjudication include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, BUCA, and Medicare.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    67028Intravitreal injection of a pharmacologic agent (separate procedure)Commonly performed before or after novel ocular procedures when medical therapy is delivered; may be part of combined visit documentation.
    92250Fundus photography with interpretation and reportMay be performed as a diagnostic adjunct to an atypical ophthalmic procedure billed with 92499.
    92083Extended visual function testing (visual field exam)Visual function testing often precedes or follows specialized procedures to establish baseline or outcomes.
    65778Corneal transplantation, lamellar (partial thickness)When an unusual adjunctive procedure or modification not described by existing codes occurs, 92499 may capture the atypical component alongside definitive surgery codes.
    99024Postoperative follow-up visit global period, related to surgical procedureUsed for routine postoperative visits; documentation must separate any additional distinct services billed with 92499.
    97140Manual therapy techniques (used rarely in periocular rehabilitation)Occasionally used in multidisciplinary workflows where unusual therapeutic manipulation or rehabilitation adjuncts are needed with ophthalmic care.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    174400000X
    261QP2300X
    207L00000X
    363A00000X
    2255R0406X
    207ZP0104X
    332G00000X

    Related Payer Policy Updates

    Specialty: Ophthalmology/Optometry1 / 2

    10 rows

    PolicyPayerEffective Date
    Corneal Remodeling for Refractive Errors and Corneal Grafting and TransplantationHealth-New-England2027-02-01
    Glaucoma Agents iDose TR (travoprost intracameral implant)Mass General Brigham Health Plan2027-01-04
    Topical Treatments for Dry Eye Diseaseblue cross blue shield - louisiana2027-01-01
    Corneal Collagen Cross-LinkingMass General Brigham Health Plan2026-11-01
    Intraocular Lens ImplantCigna2026-11-01
    VizzCigna2026-11-01
    Travoprost Intracameral ImplantBluecross Idaho2026-11-01
    Ophthalmology - Pilocarpine 1.25%Cigna2026-10-15
    Intravitreal and PunctumBlue Cross Blue Shield - Rhode Island2026-10-01
    Cataract Removal Surgery for AdultsAnthem2026-10-01

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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