Summary & Overview
CPT 90759: Hepatitis B Three‑Antigen Vaccine, 10 mcg, Three‑Dose
CPT code 90759 denotes a three–antigen hepatitis B vaccine administered intramuscularly at a 10 mcg dose on a three‑dose schedule. As a routine immunization option, this vaccine plays a role in national hepatitis B prevention efforts across ambulatory care and public health settings. The code is used to document the vaccine product itself; appropriate vaccine administration coding may be billed in conjunction where applicable.
Key payers in the analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise clinical and billing overview, payer coverage context, and information relevant to coding and service locations. The publication summarizes how the code maps to immunization services, typical sites of service, and common operational considerations for clinics and outpatient providers.
The document does not provide state-specific guidance. It covers high-level benchmarks and policy considerations relevant to national immunization programs, explains where 90759 is used clinically, and highlights data availability limitations when specific payer policy details or related taxonomies are not provided.
Billing Code Overview
CPT code 90759 represents a hepatitis B vaccine product administered intramuscularly. It is a three–antigen hepatitis B vaccine formulated at a 10 mcg dosage per dose and delivered on a three‑dose schedule. The service is an immunization/vaccine administration intended to provide active immunization against hepatitis B virus.
Typical site of service: outpatient clinics, physician offices, public health clinics, and other ambulatory care settings where intramuscular vaccines are administered. If billing for administration services separately, include the appropriate vaccine administration codes as applicable.
Service type: Preventive immunization / vaccine administration.
Data not available in the input for associated taxonomies, ICD-10 diagnoses, related codes, and service line.
Clinical & Coding Specifications
Clinical Context
A 28-year-old adult presents to an outpatient primary care clinic seeking initiation of hepatitis B vaccination prior to planned international travel and potential occupational exposure. The patient has no prior documented hepatitis B immunization and screens negative for acute illness at visit. The clinician reviews allergies and contraindications, counsels on the three-dose series, documents informed consent, and administers an intramuscular 10 mcg dose of a three–antigen hepatitis B vaccine using CPT code 90759. The clinic documents vaccine lot number, manufacturer, expiration date, administration site, and the vaccine information statement in the medical record and schedules follow-up visits for dose two and dose three per the standard dosing interval. Typical workflow includes nursing pre‑visit intake, clinician eligibility check, vaccine administration by licensed nurse or pharmacist where allowed, electronic medical record immunization reporting, and coding/billing using 90759 for the vaccine product administered intramuscularly.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier / default | Use when no special circumstances apply to the service. |