Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.30
    OpenPayerBilling CodesTissue Examination and Culture ProceduresCPT cpt-87220-koh-microscopic-fungal-examination
    Ask Trek AI about this page

    CPT 87220: KOH Preparation and Direct Microscopic Exam for Fungal Elements

    CPT code 87220 describes direct microscopic examination of a specimen treated with potassium hydroxide (KOH) as a clearing agent to detect fungal elements in nail clippings, skin scrapings, or hair shafts; service type: microscopic diagnostic mycology procedure; typical site of service: clinical laboratory or outpatient dermatology/dermatopathology setting where a laboratory analyst or microbiologist performs KOH preparation and microscopy to identify fungal forms.

    For related coverage guidance, see recent payer policy updates: Destruction of Pre-Malignant Skin Lesions, Onychomycosis diagnostic testing and coverage, Treatment of Capillary Malformations (Port Wine Stains).

    Customize your policy alerts

    Sign up for cpt 87220 policy alerts

    Get alerted when payer policies referencing 87220 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    Table of contents

    Progress1 / 7

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • Facility ComparisonBeds, revenue & payer mix
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical & Coding Specifications

    Clinical Context

    A 45-year-old patient presents to a dermatology clinic with brittle, discolored toenails and a pruritic, scaly patch on the plantar surface of the foot. The clinician performs a focused history and physical exam and collects nail clippings and superficial skin scrapings at the visit. The specimen is sent to the clinic laboratory or an outpatient pathology/microbiology lab. A lab analyst or microbiologist prepares the sample by adding potassium hydroxide (KOH) as a clearing agent and examines the specimen microscopically for fungal elements such as hyphae or spores. Results are documented in the laboratory report and communicated to the ordering clinician for correlation with clinical findings and treatment planning. Typical site of service: outpatient dermatology clinic or outpatient laboratory. Service type: diagnostic mycological microscopy using KOH preparation (87220).

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11102Tangential biopsy of skin (e.g., shave, scoop), single lesionCollected when a small skin lesion requires tissue sampling in addition to KOH for histopathology or special stains.
    11721Debridement of nail(s) for fungal testing (e.g., trimming, scraping)Procedures to collect nail material for KOH preparation or fungal culture.
    87180Culture, fungal, other than dermatophyte, isolated organism; each culturePerformed when fungal elements seen on KOH require culture to identify organism and sensitivities.
    87186Direct fluorescent antibody (DFA) for fungal organismsAlternative or adjunct laboratory test to identify fungal organisms when microscopy is inconclusive.
    87070Culture, bacterial, any other source, including presumptive identificationMay be ordered concurrently when mixed bacterial and fungal infection is suspected.
    88305Surgical pathology, gross and microscopic examination, intermediate complexityUsed when tissue biopsy is submitted for histopathologic evaluation alongside KOH testing.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208800000X
    207L00000X
    363A00000X
    231HA2500X
    363LS0200X
    374U00000X
    372600000X
    224P00000X

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    B35.0Tinea barbae and tinea capitis
    B35.1Tinea unguium
    B35.2Tinea manuum
    B35.3Tinea pedis
    B35.8Other dermatophytoses
    B35.9Dermatophytosis, unspecified
    B36.0Pityriasis versicolor
    B36.1Tinea nigra
    B36.2White piedra
    B37.0Candidal stomatitis

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    10 rows

    PolicyPayerEffective Date
    Destruction of Pre-Malignant Skin LesionsAnthem2026-10-01
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Treatment of Capillary Malformations (Port Wine Stains)universityofutahhealthplans2026-09-28
    AnzupgoCigna2026-09-15
    Zevaskyn Coverage for Recessive Dystrophic Epidermolysis BullosaCigna2026-09-01
    Topical Acne-Non-Retinoid ProductsCigna2026-08-15
    Dermatology - Vtama Drug Quantity Management Policy - Per DaysCigna2026-08-15
    Medical Necessity Guidelines: Acne and Rosacea Medicationsharvard pilgrim health care2026-08-11
    Dermatology - Anzupgo Prior Authorization PolicyCigna2026-08-05
    Light Therapy for Dermatologic Conditionsbcbsvermont2026-08-01

    Related Codes

    CPT-87230-TOXIN-DETECTION-CELL-TISSUE-CULTURE-ASSAY

    CPT 87230: Toxin Detection by Cell/Tissue Culture

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.