CPT code 82308 denotes a laboratory assay measuring calcitonin in serum or plasma, a hormone produced by thyroid parafollicular cells. Nationally, this test serves as an important biomarker for detection and monitoring of calcitonin-secreting tumors, most notably medullary thyroid carcinoma, and informs diagnostic evaluation and surveillance pathways. Coverage and payment vary across public and commercial payers; common payers included in this overview are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

Readers will find a concise explanation of the clinical purpose of CPT code 82308, common sites and service type, and the typical contexts in which calcitonin measurement is ordered. The publication summarizes payment benchmarks, billing considerations, and policy factors that affect coverage and utilization. Clinical context addresses indications for testing and how calcitonin levels are used in diagnostic workflows and tumor surveillance. Where input data is not provided, the report notes "Data not available in the input."