CPT code 81185 describes a laboratory technical service performing full gene sequencing of the CACNA1A (calcium voltage–gated channel subunit alpha1 A) gene; this is a molecular diagnostic sequencing test (technical component) typically performed as a laboratory service in a clinical molecular diagnostics or genetic testing laboratory and used to detect sequence variants across the entire coding region of the gene.

For related coverage guidance, see recent payer policy updates: RTM Testing of Homocysteine Metabolism-Related Conditions, Multimarker Serum Testing Related to Ovarian Cancer, Genomic Profiling for Selecting Targeted Cancer Therapies.