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    v1.0.30
    OpenPayerBilling CodesRadiation Hyperthermia TreatmentCPT cpt-77610-intratumoral-hyperthermia-probe-insertion
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    CPT 77610: Intratumoral Hyperthermia Probe Placement

    Medicare pays $470 on average nationally for this procedure.

    CPT code 77610 describes insertion of a single probe or needle, or an array of up to five probes or needles, into a tumor to deliver intratumoral hyperthermia that heats tissue to higher temperatures than external hyperthermia techniques; service type: therapeutic interventional procedure (local ablative/thermal therapy); typical site of service: hospital outpatient department, ambulatory surgery center, or interventional oncology suite.

    For related coverage guidance, see recent payer policy updates: Intraosseous Basivertebral Nerve Ablation for Child Health Plus (CHP) and Essential Plan (EP) Members, Acupuncture Services Payment Policy, Drug Testing in Pain Management and Substance Use Disorder.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with a localized solid tumor (for example, recurrent superficial bladder tumor, soft tissue sarcoma, or localized pelvic tumor) who has failed or is not a candidate for surgery or additional radiation. The patient presents to an outpatient interventional oncology or radiation oncology suite. Pre-procedure evaluation includes imaging review (CT/MRI or ultrasound), laboratory assessment (coagulation, CBC), informed consent, and anesthesia planning (local, monitored anesthesia care, or general anesthesia). The provider uses image guidance to place a single probe, needle, or an array of up to five probes per portal into the tumor target and delivers regional hyperthermia to raise tumor temperature above levels achievable with external applicators. Procedural workflow: patient arrival and time-out, sterile preparation, image-guided probe insertion, controlled heating delivery with temperature monitoring, probe removal, hemostasis, post-anesthesia recovery, and discharge with post-procedure instructions and analgesia plan. The typical site of service is an outpatient procedure room, ambulatory surgery center, or hospital outpatient department depending on complexity and anesthesia needs.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    10021Fine needle aspiration without imaging guidancePerformed prior to hyperthermia for cytologic diagnosis or tissue confirmation when appropriate.
    77012CT guidance for needle placementUsed to guide probe or needle placement into deep or difficult-to-access tumors prior to hyperthermia delivery.
    76942Ultrasonic guidance for needle placementUsed to guide probe insertion for superficially located tumors during hyperthermia procedures.
    76930Ultrasonic guidance for vascular accessUsed when ultrasound guidance is needed for vascular access related to procedural sedation or monitoring.
    99070Supplies and materials (e.g., sterile disposable probes)Reports separately billable expendable supplies and specialized disposables used during hyperthermia.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    207L00000X
    207K00000X
    332900000X
    207WX0120X
    174V00000X
    2085H0002X
    207RB0002X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    C18.9Malignant neoplasm of colon, unspecified
    C20Malignant neoplasm of rectum
    C22.0Liver cell carcinoma
    C25.9Malignant neoplasm of pancreas, unspecified
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    C50.911Malignant neoplasm of unspecified site of right female breast
    C61Malignant neoplasm of prostate
    C64.9Malignant neoplasm of unspecified kidney, except renal pelvis
    C67.9Malignant neoplasm of bladder, unspecified
    C71.9Malignant neoplasm of brain, unspecified

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Pain Management1 / 3

    10 rows

    PolicyPayerEffective Date
    Intraosseous Basivertebral Nerve Ablation for Child Health Plus (CHP) and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Acupuncture Services Payment Policyfallon_community_health_plan_inc2026-12-01
    Drug Testing in Pain Management and Substance Use Disorderbcbsvermont2026-11-01
    Lysis of Epidural Adhesionsexcellus_health_plan_inc2026-10-15
    Intradiscal Proceduresexcellus_health_plan_inc2026-10-15
    Radiofrequency Facet and Sacroiliac Joint Ablation/ Denervationuniverahealthcare2026-10-15
    Facet Joint Injections/ Medial Branch Blocksuniverahealthcare2026-10-15
    Lysis of Epidural Adhesions (Epidural Adhesiolysis)univerahealthcare2026-10-15
    Epidural Steroid Injections / Selective Nerve Root Block (SNRB)univerahealthcare2026-10-15
    Prolotherapyuniverahealthcare2026-10-15

    Related Codes

    CPT-77600-SUPERFICIAL-HYPERTHERMIA-UP-TO-4CM

    CPT 77600: Superficial Hyperthermia, Up to 4 cm

    CPT-77605-DEEP-THERAPEUTIC-HYPERTHERMIA

    CPT 77605: Deep Tissue Hyperthermia Treatment

    CPT-77615-INVASIVE-TUMOR-DIRECTED-HYPERTHERMIA-MULTIPLE-PROBES

    CPT 77615: Insertion of Probe Array for Tumor Hyperthermia

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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