CPT code 77280 denotes a simple radiation therapy simulation service in which a provider uses a simulator or other imaging modality to determine the size and location of ports for radiation delivery. As the initial planning step for straightforward radiation treatments, this code standardizes billing for basic simulation procedures that establish beam geometry and patient positioning.

Key national payers included in this analysis are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication outlines which payers recognize and reimburse CPT code 77280, common billing modifiers that may be applied, and the clinical context distinguishing simple from more complex simulation services.

Readers will find benchmarks and policy-relevant details, including typical sites of service (radiation oncology departments, hospital outpatient departments, and freestanding radiation therapy centers), the clinical intent of the service, and operational considerations for coding and claims submission. Where specific payer policies or rates are not provided in the input, the text notes that data are not available in the input. This national overview is intended to orient clinicians, billing professionals, and policy analysts to the role of CPT code 77280 in radiation therapy workflows and billing practices.