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    v1.0.28
    OpenPayerBilling CodesVitreous Procedures on the Posterior Segment of the EyeCPT cpt-67043-pars-plana-vitrectomy-subretinal-membrane-removal
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    CPT 67043: Pars Plana Vitrectomy with Subretinal Membrane Removal

    Medicare pays $1032 on average nationally for this procedure.

    CPT code 67043 describes a pars plana vitrectomy with removal of a subretinal membrane to treat neovascular proliferation obstructing vision, commonly used for complications of age-related macular degeneration; the service is a surgical retinal procedure typically performed in an ambulatory surgery center or hospital operating room and may include intraocular tamponade (air, gas, or silicone oil) and adjunctive retinal laser treatment as indicated.

    For related coverage guidance, see recent payer policy updates: Evaluation of Dry Eyes, Evaluation of Dry Eyes, Ophthalmic Prostaglandin Analog Prior Authorization Criteria.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 76-year-old patient with progressive vision loss in the right eye due to neovascular (wet) age-related macular degeneration presents with decreased central vision, metamorphopsia, and a fibrovascular subretinal membrane on clinical exam and optical coherence tomography (OCT). After unsuccessful or incomplete response to intravitreal anti-VEGF therapy and evidence of a contractile subretinal membrane causing persistent hemorrhage and retinal traction, the retinal surgeon schedules a pars plana vitrectomy with subretinal membrane removal (67043). The typical clinical workflow includes preoperative evaluation with OCT, fluorescein angiography as indicated, informed consent, general or monitored anesthesia care, intraoperative core and peripheral vitrectomy using a vitreous cutter, delicate removal of the subretinal membrane, possible endolaser photocoagulation, and intraocular tamponade with air, gas (eg, SF6 or C3F8), or silicone oil if required. Postoperative care includes topical antibiotics and corticosteroids, intraocular pressure monitoring, positioning instructions if gas is used, and follow-up visits with retinal imaging to assess macular anatomy and visual recovery.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    67043Removal of vitreous, pars plana vitrectomy, with removal of subretinal membrane; includes possible use of internal tamponade and endolaserPrimary procedure described.

    67036 | Vitrectomy, pars plana; for removal of vitreous with or without dye, limited therapeutic procedures | May be billed for less extensive vitrectomy when membrane removal is not performed or for the contralateral eye in a staged approach.

    67108 | Repair of retinal detachment; with vitrectomy, with internal tamponade | Performed when retinal detachment is present or occurs intra-/postoperatively requiring repair beyond membrane removal.

    67028 | Photocoagulation of retina (laser) (eg, focal or panretinal) | Used intraoperatively or postoperatively for treating retinal tears or areas of pathology adjacent to membrane removal.

    67121 | Vitreous shaving or membrane peel (complex) — Note: not an exact CPT title match; included as a related macular membrane procedure | Performed when additional macular membrane peeling (epiretinal membrane) is indicated in the same surgical setting.

    99143 | Moderate sedation services provided by an independent practitioner, per 15 minutes | Used if monitored anesthesia care with moderate sedation is billed separately during the procedure.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207W00000XOphthalmology PhysicianAn ophthalmologist has the knowledge and professional skills needed to provide comprehensive eye and vision care. Ophthalmologists are medically train…
    2251H1200XHand Physical TherapistRespiratory, Developmental, Rehabilitative and Restorative Service Providers · Physical Therapist
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    2471C3401XComputed Tomography Radiologic TechnologistA radiologic technologist who specializes in computed tomography (CT) and is appropriately educated and trained, consistent with nationally recognized…
    207ZM0300XMedical Microbiology PhysicianA medical microbiologist is expert in the isolation and identification of microbial agents that cause infectious disease. Viruses, bacteria and fungi,…
    343800000XSecured Medical Transport (VAN)A public or privately owned transportation service with vehicles, specially equipped to provide enhanced safety, security and passenger restraint, and…
    246ZG1000XMedical Geneticist (PhD) Specialist/TechnologistTechnologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Other
    246ZX2200XOrthopedic AssistantAn Orthopaedic Assistant is a person who has been trained to work as a physician extender in both clinical and surgical environments. An Orthopaedic A…

    Related ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    H35.30Unspecified macular degeneration
    H35.351Cystoid macular degeneration, right eye
    H35.352Cystoid macular degeneration, left eye
    H35.353Cystoid macular degeneration, bilateral
    H35.381Toxic maculopathy, right eye
    H35.382Toxic maculopathy, left eye

    Related Payer Policy Updates

    Specialty: Ophthalmology/Optometry1 / 2

    4 rows

    PolicyPayerEffective Date
    Evaluation of Dry EyesOscar Health2026-10-01
    Evaluation of Dry EyesBlue Cross Blue Shield - New Mexico2026-09-04
    Ophthalmic Prostaglandin Analog Prior Authorization Criteriamedimpact2026-09-01
    revakinagene taroretcel-lwey (Encelto) coverage for idiopathic macular telangiectasia (MacTel) type 2blue cross blue shield - louisiana2026-09-01

    Related Codes

    CPT-67005-ANTERIOR-VITRECTOMY-VITREOUS-REMOVAL

    CPT 67005: Anterior Vitrectomy (Vitreous Removal)

    CPT-67010-ANTERIOR-VITRECTOMY-MECHANICAL-VITREOUS-REMOVAL

    CPT 67010: Anterior Vitrectomy via Limbus/Cornea Approach

    CPT-67015-POSTERIOR-SEGMENT-NEEDLE-ASPIRATION-PARS-PLANA

    CPT 67015: Pars Plana Needle Aspiration of Ocular Fluid

    CPT-67025-VITREOUS-SUBSTITUTE-INJECTION-VITRECTOMY

    CPT 67025: Injection of Vitreous Substitute (Gas/Silicone)

    CPT-67027-VITREAL-IMPLANT-SUSTAINED-DRUG-DELIVERY-PARTIAL-VITRECTOMY

    CPT 67027: Vitrectomy with Intravitreal Sustained‑Release Implant

    CPT-67028-INTRAVITREAL-INJECTION-VITREOUS-CHAMBER

    CPT 67028: Intravitreal Injection, Isolated Procedure

    CPT-67030-PARS-PLANA-VITREOUS-STRAND-SECTION

    CPT 67030: Pars Plana Vitreous Strand Lysis

    CPT-67031-LASER-VITREOUS-REMOVAL-VISION-OBSTRUCTION

    CPT 67031: Laser Removal of Vitreous Material

    CPT-67036-POSTERIOR-SEGMENT-VITRECTOMY-PARS-PLANA

    CPT 67036: Pars Plana Vitrectomy for Posterior Segment Access

    CPT-67039-PARS-PLANA-VITRECTOMY-POSTERIOR-SEGMENT-RETINAL-TREATMENT

    CPT 67039: Pars Plana Vitrectomy with Localized Retinal Treatment

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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