CPT code 66625 denotes an ophthalmic surgical procedure in which a full-thickness piece of the iris is excised by creating a hole in the peripheral iris to treat glaucoma. This anterior segment procedure is used to address mechanisms such as pupillary block or other anatomic contributors to elevated intraocular pressure and can be performed in ambulatory surgical centers or hospital outpatient departments. Nationally, accurate coding for this procedure matters for clinical documentation, appropriate reimbursement, and tracking surgical trends in glaucoma care.

Key payers covered in this overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of the clinical intent of the code, expected sites of service, and common billing considerations. The publication also provides benchmarks and payer coverage context where available, highlights coding relationships to other anterior segment procedures, and summarizes policy and documentation points relevant to payers and health systems. Data not available in the input is noted where applicable, and the write-up focuses on the national policy and clinical context rather than jurisdiction-specific rules.