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    v1.0.30
    OpenPayerBilling CodesOther Procedures of the Endocrine SystemCPT cpt-60661-thyroid-nodule-radiofrequency-ablation-addon-lobe
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    CPT 60661: Percutaneous Radiofrequency Ablation of Additional Thyroid Lobe

    Medicare pays $422 on average nationally for this procedure.

    CPT code 60661 describes an add‑on percutaneous radiofrequency ablation procedure used to ablate one or more thyroid nodules on an additional lobe after treatment of the first lobe or the isthmus; the service includes imaging guidance and is typically performed as a minimally invasive, image‑guided thyroid nodule ablation (service type: percutaneous radiofrequency ablation, typical site of service: outpatient interventional radiology suite or ambulatory surgical center).

    For related coverage guidance, see recent payer policy updates: Diabetic Supplies, Radiofrequency Ablation for Thyroid Nodules, Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 45–65 year-old adult presenting with one or more symptomatic or growing benign thyroid nodules causing cosmetic concerns, local compressive symptoms, or persistent cystic nodules after aspiration. The patient has undergone preprocedural evaluation including thyroid ultrasound mapping, fine-needle aspiration when indicated, baseline labs (thyroid-stimulating hormone), and informed consent discussing thermal ablation risks. During a single session a treating interventional radiologist, endocrinologist with procedural privileges, or otolaryngologist performs percutaneous radiofrequency ablation (RFA) of nodules in one thyroid lobe or the isthmus under real-time ultrasound guidance. If additional nodules are present in the contralateral lobe or an additional ipsilateral lobe after treatment of the first lobe or isthmus, 60661 is reported as the add-on code for ablation of one or more nodules on that additional lobe. Imaging guidance is included in the code. Typical workflow: preprocedure ultrasound localization and marking, conscious sedation or local anesthesia administration, ultrasound-guided needle placement, thermal ablation of the targeted nodules, immediate postablation ultrasound assessment for complication (hematoma, voice changes), and short postprocedure observation with discharge instructions and follow-up ultrasound at 1–6 months.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    60659Percutaneous ablation of thyroid nodule; single lobe or isthmus (includes imaging guidance)Primary procedure code for the initial ablation of one lobe or the isthmus; 60661 is reported as an add-on when an additional lobe is treated after 60659.
    76942Ultrasonic guidance for needle placement (e.g., biopsy, aspiration, injection)Often reported when separate ultrasound guidance for needle placement is billed by a different provider; note that 60661 includes imaging guidance when billed as part of the ablation by the performing provider.
    49440Image-guided percutaneous ablation of soft tissue tumor (e.g., liver, kidney) — example image-guided ablation codeExample related image-guidance ablation codes for cross-reference; used when coding other ablation sites in the same facility or for coder comparison of technique and documentation requirements.
    76937Ultrasound guidance for vascular access device placement, imaging supervision and interpretationMay be used in the same encounter if vascular access for sedation/monitoring requires separate guidance services.
    99024Postoperative follow-up visit global period, normally includedPostprocedure follow-up care is typically bundled in the global period of ablation codes; additional visits only billed when outside global period or for unrelated services.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    207L00000X
    363LA2200X
    133VN1201X
    207RI0008X
    364SI0800X
    261QM0855X
    1835P1300X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    C73Malignant neoplasm of thyroid gland
    D34Benign neoplasm of thyroid gland
    E01.0Iodine-deficiency related diffuse (endemic) goiter
    E02Subclinical iodine-deficiency hypothyroidism
    E03.9Hypothyroidism, unspecified
    E04.1Nontoxic single thyroid nodule
    E04.2Nontoxic multinodular goiter
    E04.9Nontoxic goiter, unspecified
    E05.10Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm
    E05.11Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 2

    10 rows

    PolicyPayerEffective Date
    Diabetic SuppliesCigna2026-10-15
    Radiofrequency Ablation for Thyroid NodulesCigna2026-10-15
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only)UnitedHealthcare2026-10-01
    Tzield (teplizumab-mzwv) CoverageUnitedHealthcare2026-10-01
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Indiana Only)UnitedHealthcare2026-10-01
    Medical Necessity Guidelines Insulin PumpsMass General Brigham Health Plan2026-10-01
    Medical Necessity Guidelines: Continuous Glucose MonitorsMass General Brigham Health Plan2026-10-01
    Continuous Glucose MonitoringAmbetter Nevada2026-10-01
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01

    Related Codes

    CPT-60660-THYROID-RADIOFREQUENCY-ABLATION-PERCUTANEOUS

    CPT 60660: Percutaneous Radiofrequency Ablation of Thyroid Nodule

    CPT-60699-UNLISTED-ENDOCRINE-PROCEDURE

    CPT 60699: Endocrine System Procedure, Unlisted

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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