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CPT 58543: Laparoscopic Subtotal Hysterectomy for Enlarged Uterus (>250 g)

Headline: CPT code 58543: Laparoscopic Subtotal Hysterectomy for Enlarged Uterus — Clinical and Payer Overview

Lead: CPT code 58543 designates a laparoscopic subtotal (supracervical) hysterectomy performed for an enlarged uterus—commonly from fibroids—where the uterine weight exceeds 250 grams and the cervix and adnexa are preserved. This procedure is an important surgical option in gynecologic care due to its role in managing symptomatic fibroid disease while retaining the cervix and ovaries when clinically appropriate.

Why it matters nationally: Use of minimally invasive hysterectomy techniques affects surgical outcomes, resource utilization, and payer reimbursement strategies across settings. CPT code 58543 captures a specific clinical scenario (enlarged uterus >250 g) that can influence operative complexity, operative time, and site-of-service decisions.

Key payers covered: Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

What readers will learn: The publication provides clinical context for CPT code 58543, outlines typical sites of service and procedure intent, and summarizes the payer landscape covered in the analysis. Where available, readers will find benchmarking and policy updates related to coverage and coding practices, plus procedural considerations for claims submission. If specific data elements were not provided in the source, the publication notes that those fields are not available.

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Billing Code Overview

CPT code 58543 describes a laparoscopic subtotal (supracervical) hysterectomy performed when the uterus is enlarged—typically due to fibroids—resulting in a uterine weight greater than 250 grams. In this procedure the uterus is removed via laparoscopy while the cervix and the fallopian tubes and ovaries are left in place.

Service type: Laparoscopic gynecologic surgery — subtotal hysterectomy for enlarged uterus (fibroid-related)

Typical site of service: Hospital outpatient surgical suite or ambulatory surgery center, where laparoscopic gynecologic procedures are commonly performed.

Data not available in the input.

Find policies, billing codes, payers, states, and providers

CPT 58543: Laparoscopic Subtotal Hysterectomy for Enlarged Uterus (>250 g)

Headline: CPT code 58543: Laparoscopic Subtotal Hysterectomy for Enlarged Uterus — Clinical and Payer Overview

Key payers covered: Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

Customize your policy alerts

Sign up for cpt 58543 policy alerts

Get alerted when payer policies referencing 58543 are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Billing Code Overview

Service type: Laparoscopic gynecologic surgery — subtotal hysterectomy for enlarged uterus (fibroid-related)

Typical site of service: Hospital outpatient surgical suite or ambulatory surgery center, where laparoscopic gynecologic procedures are commonly performed.

Data not available in the input.

Clinical & Coding Specifications

Clinical Context

A typical patient is a premenopausal woman in her 40s presenting with symptomatic uterine fibroids causing heavy menstrual bleeding, pelvic pressure, and anemia. Conservative measures (medical therapy, levonorgestrel IUD, or tranexamic acid) were attempted or are contraindicated, and imaging (transvaginal ultrasound or pelvic MRI) demonstrates a uterus enlarged by fibroids with estimated uterine weight >250 g. The surgical plan is a laparoscopic supracervical hysterectomy (58543) performed under general anesthesia. The clinical workflow includes preoperative evaluation (history, physical, CBC, pregnancy test if of reproductive potential), informed consent discussing removal of the uterine corpus while retaining the cervix and ovaries/tubes if indicated, perioperative prophylactic antibiotics, laparoscopic entry (umbilical or alternative port), uterine vessel sealing, division of the corpus from the cervix, specimen removal (morcellation or mini-laparotomy if needed), hemostasis, and postoperative recovery with instructions for activity, pain control, and follow-up. Typical site of service is an ambulatory surgery center or hospital operating room. Common intraoperative considerations include management of large fibroids that may necessitate morcellation (if appropriate), conversion to open hysterectomy if visualization or bleeding is uncontrolled, and documentation of uterine weight >250 g in the operative note.

Coding Specifications

Modifier	Description	When to Use
`22`	Increased procedural services	Use when work required is substantially greater than typical for `58543` (must be well documented).
`52`	Reduced services	Use when the procedure is partially performed or curtailed (e.g., aborted due to adhesions).
`53`	Discontinued procedure	Use when the procedure is terminated after anesthesia due to extenuating circumstances.
`62`	Two surgeons	Use when two surgeons of different specialties perform distinct portions of the procedure.
`63`	Procedure performed on infants less than 4 kg	Rare for this CPT; generally not applicable but included if documentation supports.
`66`	Surgical team concept	Use when a surgical team (multiple surgeons functioning as a unit) is used and payer allows.
`74`	Discontinued outpatient hospital/ASC procedure after anesthesia	Use when the patient fails to regain consciousness or procedure stopped post-anesthesia induction.
`78`	Unplanned return to OR for related procedure during global period	Use when patient returns to OR for complication related to `58543` during the global period.
`80`	Assistant surgeon	Use when an assistant surgeon provides intraoperative assistance and is paid separately.
`AS`	Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery	Use when an advanced practice clinician assists in the procedure and billing rules permit.
`51`	Multiple procedures	Use when additional procedures are performed at the same session (list primary procedure first).

Taxonomy Code	Specialty	Notes
`208000000X`	Obstetrics & Gynecology	Generalist gynecologic surgeons performing hysterectomy.
`207V00000X`	Gynecologic Oncology	Gynecologic oncologists when complex pathology or malignancy suspected.
`2087C0002X`	Female Pelvic Medicine & Reconstructive Surgery	Surgeons addressing concurrent pelvic floor issues.
`368A00000X`	General Surgery	General surgeons may be involved if conversion to open abdominal approach is required.
`163WL0500X`	Reproductive Endocrinology/Infertility	Uncommonly involved; typically not primary for supracervical hysterectomy but relevant for fertility counseling if ovaries preserved.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`N92.0`	Excessive and frequent menstruation with regular cycle	Heavy menstrual bleeding from fibroids is a common indication for `58543`.
`D25.9`	Leiomyoma of uterus, unspecified	Uterine fibroids are the most frequent indication when the uterus is enlarged (>250 g).
`N80.0`	Endometriosis of uterus (adenomyosis)	Adenomyosis may cause bulk symptoms and bleeding prompting hysterectomy.
`N93.9`	Abnormal uterine and vaginal bleeding, unspecified	Used when specific cause not otherwise specified prior to definitive pathology.
`N76.0`	Acute vaginitis	Include when concurrent pelvic infection is assessed and managed preoperatively; active infection may alter timing of surgery.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`58974`	Uterine morcellation, intra-abdominal, for specimen removal	Performed when laparoscopic removal of a large uterine specimen requires morcellation during `58543`.
`51925`	Repair of cystotomy with suture (injury to bladder)	Relevant as a potential intraoperative repair code if urinary tract injury occurs during hysterectomy.
`57425`	Colposcopy of cervix, diagnostic, with biopsy(s)	May be performed preoperatively for abnormal cervix findings prior to deciding on supracervical hysterectomy.
`58611`	Laparoscopy, surgical; with uterine artery ligation (for laparoscopic hysterectomy)	Represents steps of vascular control that overlap with technical components of `58543` when separately reportable.
`99024`	Postoperative follow-up visit global period related to surgery	Used for significant pre- or postoperative visits related to the surgical global period when payer allows separate billing.

CPT 58541: Laparoscopic Subtotal Hysterectomy, Uterus Removed; Cervix Preserved

CPT-58542-LAPAROSCOPIC-SUBTOTAL-HYSTERECTOMY-SUPRACERVICAL

CPT 58542: Laparoscopic Subtotal (Supracervical) Hysterectomy

CPT-58544-LAPAROSCOPIC-SUPRACERVICAL-HYSTERECTOMY-ENLARGED-UTERUS

CPT 58544: Laparoscopic Supracervical Hysterectomy for Enlarged Uterus

CPT-58545-LAPAROSCOPIC-MYOMECTOMY-1-TO-4-FIBROIDS-UP-TO-250G

CPT 58545: Laparoscopic Myomectomy, 1–4 Fibroids (≤250 g)

CPT-58546-LAPAROSCOPIC-MYOMECTOMY-MULTIPLE-OR-MASSIVE-FIBROIDS

CPT 58546: Laparoscopic Myomectomy for Multiple or Large Fibroids

CPT-58548-LAPAROSCOPIC-RADICAL-HYSTERECTOMY-BSO-PELVIC-LYMPHADENECTOMY

CPT 58548: Laparoscopic Radical Hysterectomy with BSO and Pelvic Lymphadenectomy

CPT-58550-LAPAROSCOPIC-ASSISTED-VAGINAL-HYSTERECTOMY-NORMAL-UTERUS

CPT 58550: Laparoscopic-Assisted Vaginal Hysterectomy, Normal-Size Uterus

CPT-58552-VAGINAL-HYSTERECTOMY-WITH-LAPAROSCOPIC-ASSISTANCE

CPT 58552: Vaginal Hysterectomy With Laparoscopic Assistance

CPT-58553-LAPAROSCOPICALLY-ASSISTED-VAGINAL-HYSTERECTOMY-ENLARGED-UTERUS

CPT 58553: Laparoscopically Assisted Vaginal Hysterectomy for Enlarged Uterus

CPT-58554-VAGINAL-HYSTERECTOMY-LAPAROSCOPIC-ASSISTED-LARGE-UTERUS

CPT 58554: Vaginal Hysterectomy with Laparoscopic Assistance for Large Uterus

Showing 1–10 of 25

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Jul 29, 2026.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Modifier	Description	When to Use
`22`	Increased procedural services	Use when work required is substantially greater than typical for `58543` (must be well documented).
`52`	Reduced services	Use when the procedure is partially performed or curtailed (e.g., aborted due to adhesions).
`53`	Discontinued procedure	Use when the procedure is terminated after anesthesia due to extenuating circumstances.
`62`	Two surgeons	Use when two surgeons of different specialties perform distinct portions of the procedure.
`63`	Procedure performed on infants less than 4 kg	Rare for this CPT; generally not applicable but included if documentation supports.
`66`	Surgical team concept	Use when a surgical team (multiple surgeons functioning as a unit) is used and payer allows.
`74`	Discontinued outpatient hospital/ASC procedure after anesthesia	Use when the patient fails to regain consciousness or procedure stopped post-anesthesia induction.
`78`	Unplanned return to OR for related procedure during global period	Use when patient returns to OR for complication related to `58543` during the global period.
`80`	Assistant surgeon	Use when an assistant surgeon provides intraoperative assistance and is paid separately.
`AS`	Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery	Use when an advanced practice clinician assists in the procedure and billing rules permit.
`51`	Multiple procedures	Use when additional procedures are performed at the same session (list primary procedure first).

Taxonomy Code	Specialty	Notes
`208000000X`	Obstetrics & Gynecology	Generalist gynecologic surgeons performing hysterectomy.
`207V00000X`	Gynecologic Oncology	Gynecologic oncologists when complex pathology or malignancy suspected.
`2087C0002X`	Female Pelvic Medicine & Reconstructive Surgery	Surgeons addressing concurrent pelvic floor issues.
`368A00000X`	General Surgery	General surgeons may be involved if conversion to open abdominal approach is required.
`163WL0500X`	Reproductive Endocrinology/Infertility	Uncommonly involved; typically not primary for supracervical hysterectomy but relevant for fertility counseling if ovaries preserved.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`N92.0`	Excessive and frequent menstruation with regular cycle	Heavy menstrual bleeding from fibroids is a common indication for `58543`.
`D25.9`	Leiomyoma of uterus, unspecified	Uterine fibroids are the most frequent indication when the uterus is enlarged (>250 g).
`N80.0`	Endometriosis of uterus (adenomyosis)	Adenomyosis may cause bulk symptoms and bleeding prompting hysterectomy.
`N93.9`	Abnormal uterine and vaginal bleeding, unspecified	Used when specific cause not otherwise specified prior to definitive pathology.
`N76.0`	Acute vaginitis	Include when concurrent pelvic infection is assessed and managed preoperatively; active infection may alter timing of surgery.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`58974`	Uterine morcellation, intra-abdominal, for specimen removal	Performed when laparoscopic removal of a large uterine specimen requires morcellation during `58543`.
`51925`	Repair of cystotomy with suture (injury to bladder)	Relevant as a potential intraoperative repair code if urinary tract injury occurs during hysterectomy.
`57425`	Colposcopy of cervix, diagnostic, with biopsy(s)	May be performed preoperatively for abnormal cervix findings prior to deciding on supracervical hysterectomy.
`58611`	Laparoscopy, surgical; with uterine artery ligation (for laparoscopic hysterectomy)	Represents steps of vascular control that overlap with technical components of `58543` when separately reportable.
`99024`	Postoperative follow-up visit global period related to surgery	Used for significant pre- or postoperative visits related to the surgical global period when payer allows separate billing.

CPT 58541: Laparoscopic Subtotal Hysterectomy, Uterus Removed; Cervix Preserved

CPT-58542-LAPAROSCOPIC-SUBTOTAL-HYSTERECTOMY-SUPRACERVICAL

CPT 58542: Laparoscopic Subtotal (Supracervical) Hysterectomy

CPT-58544-LAPAROSCOPIC-SUPRACERVICAL-HYSTERECTOMY-ENLARGED-UTERUS

CPT 58544: Laparoscopic Supracervical Hysterectomy for Enlarged Uterus

CPT-58545-LAPAROSCOPIC-MYOMECTOMY-1-TO-4-FIBROIDS-UP-TO-250G

CPT 58545: Laparoscopic Myomectomy, 1–4 Fibroids (≤250 g)

CPT-58546-LAPAROSCOPIC-MYOMECTOMY-MULTIPLE-OR-MASSIVE-FIBROIDS

CPT 58546: Laparoscopic Myomectomy for Multiple or Large Fibroids

CPT-58548-LAPAROSCOPIC-RADICAL-HYSTERECTOMY-BSO-PELVIC-LYMPHADENECTOMY

CPT 58548: Laparoscopic Radical Hysterectomy with BSO and Pelvic Lymphadenectomy

CPT-58550-LAPAROSCOPIC-ASSISTED-VAGINAL-HYSTERECTOMY-NORMAL-UTERUS

CPT 58550: Laparoscopic-Assisted Vaginal Hysterectomy, Normal-Size Uterus

CPT-58552-VAGINAL-HYSTERECTOMY-WITH-LAPAROSCOPIC-ASSISTANCE

CPT 58552: Vaginal Hysterectomy With Laparoscopic Assistance

CPT-58553-LAPAROSCOPICALLY-ASSISTED-VAGINAL-HYSTERECTOMY-ENLARGED-UTERUS

CPT 58553: Laparoscopically Assisted Vaginal Hysterectomy for Enlarged Uterus

CPT-58554-VAGINAL-HYSTERECTOMY-LAPAROSCOPIC-ASSISTED-LARGE-UTERUS

CPT 58554: Vaginal Hysterectomy with Laparoscopic Assistance for Large Uterus

Showing 1–10 of 25

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Jul 29, 2026.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

CPT 58543: Laparoscopic Subtotal Hysterectomy for Enlarged Uterus (>250 g)

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Billing Code Overview

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CPT 58543: Laparoscopic Subtotal Hysterectomy for Enlarged Uterus (>250 g)

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Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References