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CPT 57456: Colposcopy of Cervix with Endocervical Curettage

CPT code 57456 represents colposcopy of the cervix with endocervical curettage, a diagnostic gynecologic procedure used to evaluate abnormal cervical findings and obtain tissue from the endocervical canal. Nationally, this code is important for women's health services and preventive and diagnostic pathways related to cervical dysplasia and other abnormalities detected by screening.

Key payers included in the analysis are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context, typical sites of service, and commonly reported modifiers. The publication outlines what providers and administrators need to know about billing practice patterns, coverage considerations from major payers, and common documentation elements tied to the procedure. It also summarizes typical service line placement for coding and revenue-cycle workflows.

This resource is intended to give clinicians, billers, and health policy professionals a clear baseline understanding of CPT code 57456, its clinical role in diagnosing cervical pathology, and the payer landscape relevant to national billing and coverage practices. Data not available in the input are noted where applicable.

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Billing Code Overview

CPT code 57456 describes a diagnostic procedure in which a physician performs a colposcopic examination of the cervix, including the upper or adjacent portion of the vagina, and obtains tissue via endocervical curettage using a curette (spoon-shaped scraping instrument). This combines visual inspection with targeted sampling of the endocervical canal to evaluate abnormal cervical findings.

Service type: Colposcopy with endocervical curettage (diagnostic gynecologic procedure)
Typical site of service: Outpatient clinic, physician office, or ambulatory surgical center where gynecologic diagnostic procedures are performed.

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CPT 57456: Colposcopy of Cervix with Endocervical Curettage

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Billing Code Overview

Service type: Colposcopy with endocervical curettage (diagnostic gynecologic procedure)
Typical site of service: Outpatient clinic, physician office, or ambulatory surgical center where gynecologic diagnostic procedures are performed.

Clinical & Coding Specifications

Clinical Context

A 32-year-old woman presents to an outpatient gynecology clinic after an abnormal screening Pap test showing high-grade squamous intraepithelial lesion (HSIL) on cytology. She reports intermittent postcoital spotting but no significant pelvic pain or fever. The clinician reviews prior records, obtains informed consent, and performs a focused pelvic exam. Using a colposcope, the physician inspects the cervix and the adjacent upper vagina with application of acetic acid and Lugol’s iodine to identify acetowhite lesions. Directed biopsies are taken from suspicious areas. Because the transformation zone is not fully visualized or to evaluate for possible endocervical pathology, the clinician performs endocervical curettage (ECC) with a curette to obtain tissue from the endocervical canal for histopathology. Specimens are labeled, submitted to pathology, and the patient is provided postprocedure care instructions and follow-up planning.

Coding Specifications

Modifier	Description	When to Use
`25`	Significant, separately identifiable evaluation and management service by the same physician on the same day of the procedure	Use when an E/M visit is performed in addition to the colposcopy/ECC for a separate issue or for preprocedure evaluation beyond routine consent and brief assessment.
`26`	Professional component	Use when billing for the physician’s professional interpretation only and the facility bills the technical component.
`59`	Distinct procedural service	Use if another unrelated procedure is performed on the same day that is not normally bundled with colposcopy/ECC.
`22`	Unusual procedural services — increased procedural services	Use to report unusually high complexity, longer time, or additional work beyond the typical service when well-documented.
`52`	Reduced services	Use when the procedure is partially reduced or discontinued (e.g., limited colposcopy or incomplete ECC).
`53`	Discontinued procedure	Use when the procedure is started but stopped due to patient condition or safety concerns before completion.
`76`	Repeat procedure by same physician (note: `76` not in provided list; therefore not included)	Data not available in the input.
`73`	Discontinued outpatient procedure prior to anesthesia administration	Use if colposcopy/ECC is discontinued before initiation due to a change in patient status (applicable in same-day outpatient settings).
`59`	Distinct procedural service	Duplicate entry avoided; already listed above.
`QW`	CLIA waived test performed in office	Use when any waived point-of-care tests related to the visit are performed (e.g., rapid tests documented per payer rules).

Taxonomy Code	Specialty	Notes
207Q00000X	Obstetrics & Gynecology	Most common specialty performing colposcopy with ECC.
207RG0300X	Gynecologic Oncology	Performs diagnostic colposcopy/ECC for high-grade lesions or suspected malignancy.
163W00000X	Family Medicine	Family physicians with women’s health scope may perform colposcopy and ECC in outpatient settings.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`N87.2`	Moderate cervical dysplasia (CIN II)	Common indication for colposcopy with ECC to evaluate extent of dysplastic disease.
`N87.1`	Mild cervical dysplasia (CIN I)	May prompt colposcopy when persistent or atypical features are present.
`R87.610`	HSIL (positive) on cytologic smear	High-grade cytology result frequently leads to colposcopy and ECC for tissue diagnosis.
`R87.611`	LSIL (positive) on cytologic smear	Low-grade cytology may lead to colposcopy based on age, persistence, or HPV status.
`N89.0`	Erosion of cervix	Visible cervical abnormalities identified on exam that warrant colposcopic assessment and possible ECC.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`57454`	Colposcopy of the cervix including upper/adjacent vagina when performed; diagnostic	Often performed immediately prior to or instead of `57456` when ECC is not performed; represents colposcopy without endocervical curettage.
`57500`	Biopsy of cervix, single or multiple	Directed cervical biopsies commonly performed during colposcopy in addition to or instead of `57456` for tissue diagnosis.
`58100`	Endometrial sampling (e.g., biopsy, curettage)	May be performed in the same clinical session for evaluation of abnormal uterine bleeding when indicated, separate from ECC.
`88172`	Cytopathology, cervical or vaginal (e.g., Pap) with manual screening	Laboratory services for cytology that often prompt diagnostic colposcopy and ECC.
`+88305`	Level IV surgical pathology, gross and microscopic examination	Typical pathology CPT for tissue obtained from ECC and biopsies; billed by pathology laboratory.

CPT 57452: Diagnostic Colposcopy of Cervix and Upper Vagina

CPT-57454-COLPOSCOPY-WITH-BIOPSY-ENDOCERVICAL-SAMPLING

CPT 57454: Colposcopy with Cervical Biopsy and Endocervical Sampling

CPT-57455-COLPOSCOPY-WITH-CERVICAL-BIOPSY

CPT 57455: Colposcopy of Cervix with Cervical Biopsy(ies)

CPT-57460-COLPOSCOPY-WITH-LOOP-ELECTRODE-BIOPSY

CPT 57460: Colposcopy with Loop Electrode Biopsy of Cervix

CPT-57461-COLPOSCOPY-WITH-LOOP-ELECTRODE-CONIZATION

CPT 57461: Colposcopy with Loop Electrode Conization of Cervix

CPT-57465-COMPUTER-AIDED-COLPOSCOPIC-MAPPING-CERVIX

CPT 57465: Computer-Aided Colposcopic Mapping of Cervix

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Clinical & Coding Specifications

Clinical Context

Coding Specifications

Modifier	Description	When to Use
`25`	Significant, separately identifiable evaluation and management service by the same physician on the same day of the procedure	Use when an E/M visit is performed in addition to the colposcopy/ECC for a separate issue or for preprocedure evaluation beyond routine consent and brief assessment.
`26`	Professional component	Use when billing for the physician’s professional interpretation only and the facility bills the technical component.
`59`	Distinct procedural service	Use if another unrelated procedure is performed on the same day that is not normally bundled with colposcopy/ECC.
`22`	Unusual procedural services — increased procedural services	Use to report unusually high complexity, longer time, or additional work beyond the typical service when well-documented.
`52`	Reduced services	Use when the procedure is partially reduced or discontinued (e.g., limited colposcopy or incomplete ECC).
`53`	Discontinued procedure	Use when the procedure is started but stopped due to patient condition or safety concerns before completion.
`76`	Repeat procedure by same physician (note: `76` not in provided list; therefore not included)	Data not available in the input.
`73`	Discontinued outpatient procedure prior to anesthesia administration	Use if colposcopy/ECC is discontinued before initiation due to a change in patient status (applicable in same-day outpatient settings).
`59`	Distinct procedural service	Duplicate entry avoided; already listed above.
`QW`	CLIA waived test performed in office	Use when any waived point-of-care tests related to the visit are performed (e.g., rapid tests documented per payer rules).

Taxonomy Code	Specialty	Notes
207Q00000X	Obstetrics & Gynecology	Most common specialty performing colposcopy with ECC.
207RG0300X	Gynecologic Oncology	Performs diagnostic colposcopy/ECC for high-grade lesions or suspected malignancy.
163W00000X	Family Medicine	Family physicians with women’s health scope may perform colposcopy and ECC in outpatient settings.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`N87.2`	Moderate cervical dysplasia (CIN II)	Common indication for colposcopy with ECC to evaluate extent of dysplastic disease.
`N87.1`	Mild cervical dysplasia (CIN I)	May prompt colposcopy when persistent or atypical features are present.
`R87.610`	HSIL (positive) on cytologic smear	High-grade cytology result frequently leads to colposcopy and ECC for tissue diagnosis.
`R87.611`	LSIL (positive) on cytologic smear	Low-grade cytology may lead to colposcopy based on age, persistence, or HPV status.
`N89.0`	Erosion of cervix	Visible cervical abnormalities identified on exam that warrant colposcopic assessment and possible ECC.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`57454`	Colposcopy of the cervix including upper/adjacent vagina when performed; diagnostic	Often performed immediately prior to or instead of `57456` when ECC is not performed; represents colposcopy without endocervical curettage.
`57500`	Biopsy of cervix, single or multiple	Directed cervical biopsies commonly performed during colposcopy in addition to or instead of `57456` for tissue diagnosis.
`58100`	Endometrial sampling (e.g., biopsy, curettage)	May be performed in the same clinical session for evaluation of abnormal uterine bleeding when indicated, separate from ECC.
`88172`	Cytopathology, cervical or vaginal (e.g., Pap) with manual screening	Laboratory services for cytology that often prompt diagnostic colposcopy and ECC.
`+88305`	Level IV surgical pathology, gross and microscopic examination	Typical pathology CPT for tissue obtained from ECC and biopsies; billed by pathology laboratory.

CPT 57452: Diagnostic Colposcopy of Cervix and Upper Vagina

CPT-57454-COLPOSCOPY-WITH-BIOPSY-ENDOCERVICAL-SAMPLING

CPT 57454: Colposcopy with Cervical Biopsy and Endocervical Sampling

CPT-57455-COLPOSCOPY-WITH-CERVICAL-BIOPSY

CPT 57455: Colposcopy of Cervix with Cervical Biopsy(ies)

CPT-57460-COLPOSCOPY-WITH-LOOP-ELECTRODE-BIOPSY

CPT 57460: Colposcopy with Loop Electrode Biopsy of Cervix

CPT-57461-COLPOSCOPY-WITH-LOOP-ELECTRODE-CONIZATION

CPT 57461: Colposcopy with Loop Electrode Conization of Cervix

CPT-57465-COMPUTER-AIDED-COLPOSCOPIC-MAPPING-CERVIX

CPT 57465: Computer-Aided Colposcopic Mapping of Cervix

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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CPT 57456: Colposcopy of Cervix with Endocervical Curettage

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Billing Code Overview

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CPT 57456: Colposcopy of Cervix with Endocervical Curettage

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Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References