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    OpenPayerBilling CodesExploration of EpididymisCPT cpt-54865-epididymal-exploratory-surgery-biopsy
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    CPT 54865: Exploratory Surgery of Epididymis with Possible Biopsy

    Medicare pays $344 on average nationally for this procedure.

    CPT code 54865 describes an exploratory surgical procedure of the epididymis performed to evaluate obstructive causes of azoospermia and may include an epididymal biopsy during the same operation; this is a surgical diagnostic service typically performed by urologists in an operating room or ambulatory surgical center under appropriate anesthesia and with specimen handling for pathologic assessment.

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 34-year-old male with a 12-month history of infertility presents to a urologist after two semen analyses demonstrate azoospermia. Physical exam reveals a normal testis volume with palpable vas deferens. Scrotal ultrasound shows no obvious testicular mass but suggests possible epididymal dilation. The urologist schedules an exploratory epididymal surgery with possible epididymal biopsy to evaluate for an obstructive cause of azoospermia and to obtain tissue for histopathology and possible sperm retrieval.

    The clinical workflow includes preoperative counseling and informed consent discussing risks (bleeding, infection, chronic scrotal pain), anesthesia evaluation, pre-op semen analysis and reproductive counseling, intraoperative exploration of the epididymis, targeted biopsy if indicated, possible microsurgical techniques to identify obstruction, specimen submission to pathology, and postoperative follow-up with wound check and discussion of pathology and fertility implications. Typical site of service is an outpatient ambulatory surgery center or hospital operating room under general or regional anesthesia. Service type: surgical diagnostic/exploratory procedure of the epididymis for fertility evaluation.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    54520Repair of vas deferens (vasovasostomy or vasoepididymostomy)Performed when an obstruction in the vas or epididymal outflow is identified and reconstructive repair is indicated following exploration
    54320Epididymectomy, partial or total, including ligation of vas deferens when performedMay be performed if there is irreversible epididymal pathology identified during exploration
    55400Biopsy, prostate; needle or punchNot directly performed during epididymal exploration but may be part of male infertility workup in select cases
    55866Cryopreservation (sperm) at time of surgery, when performedSperm retrieval and cryopreservation can be done if motile sperm are found during epididymal biopsy
    76930Ultrasound, scrotum, real-time with image documentationOften used preoperatively for localization and may be used intraoperatively for guidance

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    363L00000X
    207RN0300X
    207Q00000X
    2084A0401X
    2279G0305X
    133NN1002X
    133VN1101X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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