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    OpenPayerBilling CodesEndoscopy-Cystoscopy, Urethroscopy, Cystourethroscopy Procedures on the BladderCPT cpt-52007-cystourethroscopy-ureter-renal-pelvis-brush-biopsy
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    CPT 52007: Cystourethroscopy with Ureter/Renal Pelvis Brush Biopsy

    Medicare pays $448 on average nationally for this procedure.

    CPT code 52007 describes a cystourethroscopy with inspection of the bladder, urethra, and ureteric pelvis and obtaining a brush biopsy of the ureter and/or renal pelvis using a scope; this service is an endoscopic diagnostic and tissue-sampling procedure typically performed in an operating room or procedure suite and may include bladder irrigation, instillation of fluids, or imaging of the upper tracts when performed (radiologic services reported separately).

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 67-year-old male with gross hematuria and a history of smoking is scheduled for cystourethroscopy with ureteric brush biopsy (52007) performed by a urologist in an outpatient endoscopy suite. Pre-procedure evaluation includes urinalysis, urine culture, and cross-sectional imaging (CT urogram) identifying a filling defect in the renal pelvis. Under monitored anesthesia care, a flexible cystoscope is advanced to inspect the bladder and urethra. The ureteral orifice is cannulated, a ureteroscope advanced into the ureter and renal pelvis as needed, and a cytology brush is passed through the working channel to obtain brush biopsies of the ureter and/or renal pelvis. The provider may irrigate the bladder and instill topical agents during the procedure. Fluoroscopic imaging or formal radiologic contrast studies are performed separately as indicated and billed independently. Post-procedure, the patient is observed in recovery, receives discharge instructions about hematuria and infection signs, and outpatient pathology follow-up is arranged for cytology results.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    52000Cystourethroscopy (separate procedure without brush biopsy)Performed when cystoscopic inspection is done without ureteric brush biopsy; may be billed if no biopsy obtained
    52332Cystourethroscopy, with ureteroscopy and/or pyeloscopy; diagnostic, with or without collection of specimen(s) by brushing or washingAlternative code when ureteroscopy/pyeloscopy is performed and specimen collection is part of that scope-based procedure
    52005Cystourethroscopy, with insertion of ureteral catheter (diagnostic)May precede contrast studies or selective ureteral catheterization during evaluation of upper tract lesions
    52010Cystourethroscopy; with ureteral catheterization, radiologic evaluation of ureter and renal pelvisRadiologic services should be billed separately; this code applies when catheterization plus imaging of upper tract is performed
    46320Ureteral catheterization via cystoscopy (when performed in some reporting contexts)Related technical maneuver during access to ureteric orifice prior to brush biopsy

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363L00000X
    207R00000X
    208000000X
    2251N0400X
    208U00000X
    2085H0002X
    163WS0121X
    174200000X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 2

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-52000-DIAGNOSTIC-CYSTOURETHROSCOPY-BLADDER-URETHRA

    CPT 52000: Diagnostic Cystourethroscopy

    CPT-52001-CYSTOURETHROSCOPY-CLOT-EVACUATION

    CPT 52001: Cystourethroscopy with Suction/Irrigation Clot Evacuation

    CPT-52005-CYSTOURETHROSCOPY-BLADDER-URETHRA-URETERIC-PELVIS-INSPECTION

    CPT 52005: Cystourethroscopy, Bladder/Urethra/Ureteric Pelvis Inspection

    CPT-52010-CYSTOURETHROSCOPY-EJACULATORY-DUCT-CATHETERIZATION

    CPT 52010: Cystourethroscopy with Ejaculatory Duct Catheterization

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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