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    v1.0.28
    OpenPayerBilling CodesExcision Procedures on the BladderCPT cpt-51595-radical-cystectomy-urinary-diversion
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    CPT 51595: Radical Cystectomy with Urinary Diversion

    Medicare pays $1965 on average nationally for this procedure.

    CPT code 51595 describes a radical cystectomy with extensive bilateral pelvic lymphadenectomy and creation of a urinary diversion (such as a ureteroileal conduit or sigmoid neobladder) to restore urine outflow after removal of the bladder for malignancy; this is a surgical inpatient abdominal/pelvic procedure typically performed in an inpatient hospital operating room for oncologic management of bladder cancer.

    For related coverage guidance, see recent payer policy updates: Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults, Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in Adults, Site of Service Ambulatory Service Center (ASC) Select.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 68-year-old male with muscle-invasive urothelial carcinoma of the bladder scheduled for radical cystectomy with urinary diversion. The patient has undergone preoperative staging (CT chest/abdomen/pelvis) confirming organ-confined disease without distant metastases, and preoperative counseling with urology and anesthesia staff. On the day of surgery the patient receives general endotracheal anesthesia, prophylactic antibiotics, venous thromboembolism prophylaxis, and bowel preparation per institutional protocol. The surgical team performs a radical cystectomy with extensive bilateral pelvic lymph node dissection (external iliac, hypogastric/internal iliac, and obturator nodes). To reestablish urinary continuity the surgeon creates a urinary diversion such as a ureteroileal conduit or an orthotopic neobladder created from sigmoid colon (sigmoid bladder) and performs bowel anastomosis to restore continuity. Intraoperative specimens are sent to pathology. Postoperative workflow includes immediate postoperative monitoring in the PACU, inpatient surgical ward care with pain control, early mobilization, stoma care education if a conduit was created, monitoring for surgical complications (bleeding, infection, anastomotic leak, ureteral obstruction), and coordination of adjuvant oncology as indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    51596Radical cystectomy with urinary diversion, including pelvic lymphadenectomy (when specific diversion differs)Alternative or adjacent CPT code used for radical cystectomy with different diversion technique or coding variation; used when documentation specifies the alternative code descriptor.
    44120Enterectomy, resection of small intestine; single resection and anastomosisPerformed when ileal segment is resected to create a ureteroileal conduit and bowel continuity is restored.
    44140Enterolysis (freeing adhesions) when performed separatelyMay be performed intraoperatively if significant adhesions require lysis before cystectomy or diversion creation.
    49440Insertion of tunneled catheter for peritoneal dialysis or other ostomy-related procedures (stoma care codes vary)Related to creation and management of abdominal wall stoma for an ileal conduit; used for ostomy-related procedures or revisions.
    88305Surgical pathology, evaluation of a specimen with microscopic examinationUsed for histopathologic examination of the cystectomy specimen and lymph nodes submitted to pathology.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207RH0000XHematology (Internal Medicine) PhysicianAn internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, cl…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    2080P0210XPediatric Nephrology PhysicianA pediatrician who deals with the normal and abnormal development and maturation of the kidney and urinary tract, the mechanisms by which the kidney c…
    261QM1100XMilitary/U.S. Coast Guard Outpatient Clinic/CenterThe Defense Health Program or U.S. Coast Guard funded "fixed" facilities or distinct parts of a facility, providing outpatient medical and dental serv…
    2084P0015XPsychosomatic Medicine PhysicianPsychosomatic Medicine is subspecialty in the diagnosis and treatment of psychiatric disorders and symptoms in complex medically ill patients. This su…
    246R00000XPathology TechnicianAn individual with knowledge of specific techniques and instruments who performs all of the routine tests in a medical laboratory and who has the abil…
    177F00000XLodging ProviderA public or privately owned facility providing overnight lodging to individuals traveling long distances or receiving prolonged outpatient medical ser…

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    C67.0Malignant neoplasm of trigone of bladder
    C67.1Malignant neoplasm of dome of bladder
    C67.2Malignant neoplasm of lateral wall of bladder
    C67.3Malignant neoplasm of anterior wall of bladder
    C67.4Malignant neoplasm of posterior wall of bladder
    C67.5Malignant neoplasm of bladder neck
    C67.6Malignant neoplasm of ureteric orifice
    C67.7Malignant neoplasm of urachus
    C67.8Malignant neoplasm of overlapping sites of bladder
    C67.9Malignant neoplasm of bladder, unspecified

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01
    Inpatient Surgical Site of ServiceProvidence Health Plan2026-07-01
    Removal of Implantable DevicesBlue Cross Blue Shield - Rhode Island2026-07-01

    Related Codes

    CPT-51500-URACHAL-CYST-SINUS-EXCISION-UMBILICAL-HERNIA-REPAIR

    CPT 51500: Excision of Urachal Cyst or Sinus

    CPT-51520-BLADDER-NECK-EXCISION

    CPT 51520: Excision of Bladder Neck to Relieve Obstruction

    CPT-51525-BLADDER-DIVERTICULECTOMY-OPEN-EXCISION

    CPT 51525: Excision of Bladder Diverticulum

    CPT-51530-BLADDER-TUMOR-EXCISION

    CPT 51530: Excision of Bladder Tumor (Incision into Bladder)

    CPT-51535-URETEROCELE-EXCISION-REPAIR-BLADDER-INCISION

    CPT 51535: Ureterocele Excision, Incision, or Repair

    CPT-51550-PARTIAL-CYSTECTOMY-SIMPLE-CYSTECTOMY-BLADDER-RESECTION

    CPT 51550: Simple Cystectomy (Partial Bladder Removal)

    CPT-51555-COMPLEX-PARTIAL-CYSTECTOMY-BLADDER-RESECTION

    CPT 51555: Complex Partial Cystectomy

    CPT-51565-BLADDER-RESECTION-AND-URETERAL-REIMPLANTATION

    CPT 51565: Bladder Segmental Resection with Ureteral Reimplantation

    CPT-51570-RADICAL-CYSTECTOMY-COMPLETE-BLADDER-REMOVAL

    CPT 51570: Radical Cystectomy (Complete Bladder Removal)

    CPT-51575-RADICAL-CYSTECTOMY-PELVIC-LYMPHADENECTOMY

    CPT 51575: Radical Cystectomy with Pelvic Lymph Node Dissection

    Showing 1–10 of 15

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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