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    v1.0.30
    OpenPayerBilling CodesPeritoneal Cavity ProceduresCPT cpt-49400-intraperitoneal-contrast-or-air-injection-for-imaging
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    CPT 49400: Abdominal Injection of Air or Contrast for Radiologic Study

    Medicare pays $155 on average nationally for this procedure.

    CPT code 49400 describes injection of air or contrast material into the abdominal cavity to enhance visualization of intra‑abdominal organs and structures on a separately performed radiologic study; this is an image‑enhancement service typically performed as an interventional diagnostic procedure in a hospital radiology suite or outpatient imaging center and is classified as an abdominal contrast/air insufflation procedure.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult admitted to a hospital or presenting to an outpatient radiology suite for evaluation of suspected intra-abdominal pathology where enhanced visualization of abdominal organs is needed during fluoroscopic or radiographic imaging. For example, a 46-year-old female with intermittent abdominal pain and prior abdominal surgery undergoes a diagnostic radiologic study for suspected bowel obstruction or to evaluate postoperative adhesions. The interventionalist or radiologist performs an intraperitoneal air or contrast injection (peritoneal insufflation or pneumoperitoneum with air/contrast) immediately before the separately performed radiographic study to outline bowel loops, demonstrate free intraperitoneal air, or delineate organ contours. Typical workflow: pre-procedure consent and review of indications and allergies; sterile preparation and local anesthesia; insertion of a small-gauge needle or catheter into the peritoneal cavity; controlled injection of air or iodinated contrast under aseptic technique; monitoring for patient tolerance and immediate imaging performed by radiology (fluoroscopy, CT, or radiographs); post-procedure observation for complications such as bowel perforation, abdominal pain, or contrast extravasation. Typical sites of service include the hospital inpatient unit, hospital outpatient radiology department, or ambulatory surgical center depending on clinical acuity and concurrent procedures. The service is reported in conjunction with the separately performed radiological study; it represents the injection/insufflation and not the imaging interpretation or imaging technical component.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    74000Radiologic examination, abdomen, single viewOften performed immediately after insufflation to visualize abdominal organs or free air
    74022Radiologic examination, abdomen; with KUB and up to 4 additional viewsAlternative plain radiographic chest/abdomen series used after insufflation for broader evaluation
    74176Computed tomography, abdomen; without contrast materialCT may be the separately performed radiologic study that follows intraperitoneal air/contrast injection to improve delineation
    74177Computed tomography, abdomen; with contrast material(s)CT with intravascular contrast often complements intraperitoneal contrast for comprehensive evaluation
    47562Laparoscopy, surgical; cholecystectomy, laparoscopicExample of a surgical procedure where peritoneal insufflation (pneumoperitoneum) is performed as part of the operative workflow (note: 49400 reports the injection for imaging, not operative pneumoperitoneum)
    76942Ultrasonic guidance for needle placement (eg, for aspiration, biopsy, or injection)May be used when image guidance is required to place the needle/catheter for intraperitoneal injection

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363L00000X
    207K00000X
    246ZB0600X
    207XS0106X
    2355A2700X
    2086S0102X
    2279P3800X
    207Q00000X

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    C18.9Malignant neoplasm of colon, unspecified
    C48.2Malignant neoplasm of peritoneum, unspecified
    C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
    K35.80Unspecified acute appendicitis
    K36Other appendicitis
    K37Unspecified appendicitis
    K55.9Vascular disorder of intestine, unspecified
    K57.20Diverticulitis of large intestine with perforation and abscess without bleeding
    K57.30Diverticulosis of large intestine without perforation or abscess without bleeding
    K57.90Diverticulosis of intestine, part unspecified, without perforation or abscess without bleeding

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-49402-ABDOMINAL-FOREIGN-BODY-REMOVAL

    CPT 49402: Removal of Foreign Body From Abdominal Cavity

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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