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    OpenPayerBilling CodesIncision Procedures on the LiverCPT cpt-47001-liver-biopsy-add-on-procedure
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    CPT 47001: Liver Biopsy, Add-on Procedure

    Medicare pays $93 on average nationally for this procedure.

    CPT code 47001 is an add-on liver biopsy procedure performed at the same operative session as another primary procedure to obtain a small tissue sample for diagnosis, staging, or monitoring of liver disease; service type: diagnostic tissue biopsy, typical site of service: operating room, procedure suite, or interventional radiology.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient undergoing an elective abdominal surgery for suspected metastatic colon cancer has an intraoperative decision made to obtain a liver tissue sample to assess for metastatic disease. The surgeon performs a percutaneous or open liver biopsy at the same operative session as the primary procedure to provide histologic confirmation. The clinical workflow includes preoperative review of indications (abnormal liver imaging or abnormal liver function tests), obtaining informed consent that includes the add-on biopsy, coordination with pathology for specimen handling, performance of the biopsy at the time of the primary procedure, labeling and sending the specimen to pathology, and documentation in the operative report describing the biopsy technique, site, amount of tissue obtained, and any immediate complications.

    Common clinical settings include: staging of known malignancy, evaluation of unexplained abnormal liver enzymes discovered during another abdominal operation, or sampling of a focal liver lesion discovered incidentally during the primary procedure. Typical site of service is the operating room or procedural suite during another primary surgical or interventional procedure where the liver biopsy is performed concurrently as an add-on service.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    47001Liver biopsy, add-on; performed at the same time as another primary procedurePrimary code for the add-on liver biopsy performed concurrently with another principal procedure (the focus of this guidance).
    47000Liver biopsy, needle; percutaneousA standalone percutaneous liver biopsy code that may be used when the biopsy is performed as the primary procedure rather than as an intraoperative add-on.
    47010Liver biopsy, open; incisionalUsed when an open incisional liver biopsy is the primary procedure; 47001 is used when an additional biopsy is performed concurrent with another primary operation.
    10021Fine needle aspiration; without imaging guidanceMay be used for cytologic sampling of a liver lesion when a less invasive sampling is performed instead of core biopsy.
    76942Ultrasonic guidance for needle placement (eg, biopsy)Used when ultrasound guidance is used to facilitate the liver biopsy during the operative or percutaneous procedure.
    77012CT guidance for needle placement (eg, biopsy)Used when CT guidance is employed to localize and obtain the liver biopsy during a concurrent procedure.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    208000000X
    363L00000X
    207T00000X
    103TP2700X
    207WX0107X
    3104A0625X
    172A00000X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    B18.1Chronic viral hepatitis B without delta-agent
    B18.2Chronic viral hepatitis C
    C22.0Liver cell carcinoma
    C22.9Malignant neoplasm of liver, not specified as primary or secondary
    D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
    D64.9Anemia, unspecified
    E83.19Other disorders of iron metabolism
    E83.9Disorder of mineral metabolism, unspecified
    I85.01Esophageal varices with bleeding
    K70.30Alcoholic cirrhosis of liver without ascites

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-47000-PERCUTANEOUS-LIVER-BIOPSY

    CPT 47000: Percutaneous Liver Biopsy

    CPT-47010-HEPATOTOMY-LIVER-ABSCESS-CYST-DRAINAGE

    CPT 47010: Hepatotomy for Drainage of Liver Abscess or Cyst

    CPT-47015-LAPAROTOMY-ASPIRATION-INJECTION-LIVER-CYST-ABSCESS

    CPT 47015: Laparotomy with Aspiration/Injection of Liver Cyst or Abscess

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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