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    v1.0.28
    OpenPayerBilling CodesExcision Procedures on the Intestines (Except Rectum)CPT cpt-44133-living-donor-intestinal-harvest-with-anastomosis
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    CPT 44133: Living Donor Intestinal Harvest and Anastomosis

    CPT code 44133 describes a surgical procedure in which a segment of intestine is harvested from a living donor and the two severed intestinal ends are reconnected (intestinal anastomosis); the code includes cold preservation of the donor intestines. Service type: surgical organ procurement and transplant surgery. Typical site of service: inpatient operating room or transplant center.

    For related coverage guidance, see recent payer policy updates: Esophagogastroduodenoscopy (EGD) Coverage Policy, Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD), Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver Disease.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 32-year-old living donor is evaluated and selected to donate a segment of small intestine for a pediatric recipient with short bowel syndrome. Preoperative evaluation includes surgical clearance, infectious disease testing, blood type and HLA crossmatch coordination with the transplant team, and informed consent discussing risks of bowel resection and anastomotic leak. On the day of surgery the donor is brought to an operating room at an acute care hospital or transplant center. Anesthesia induction is followed by a midline laparotomy or minimally invasive approach to mobilize the intended intestinal segment. The surgeon resects the donor segment and performs an immediate primary intestinal anastomosis to restore continuity of the donor bowel. The harvested segment is flushed, placed in cold preservation solution, and transferred to the transplant team for implantation into the recipient. Postoperative workflow includes donor recovery monitoring for bowel function, pain control, infection surveillance, and discharge planning with instructions for activity and diet advancement. Typical site of service is an inpatient acute care hospital or specialized transplant center. Service type is an open or laparoscopic surgical harvest of a living donor intestinal segment with primary anastomosis and cold preservation of the graft.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    44120Enterectomy, resection of small intestine; single resection and anastomosisAn alternative code for non-donor small bowel resections; used when enterectomy is performed for donor but without transplant-specific preservation elements.
    47135Donor hepatectomy, living donor, lobe or segmentRelated living donor organ harvest code illustrating parallel workflow components (donor evaluation, resection, preservation) though for liver.
    0196TDonation of intestinal segment, living donor (harvest and transfer) — Category III example code (if applicable by payer)Some payers may track living-donor organ procurement with procedure-specific tracking codes; used alongside donor harvest documentation when available.
    Codes not providedData not available in the input.Data not available in the input.
    Codes not providedData not available in the input.Data not available in the input.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207LH0002XHospice and Palliative Medicine (Anesthesiology) PhysicianAn anesthesiologist with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illnesses. This …
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    2080P0207XPediatric Hematology & Oncology PhysicianA pediatrician trained in the combination of pediatrics, hematology and oncology to recognize and manage pediatric blood disorders and cancerous disea…
    207X00000XOrthopaedic Surgery PhysicianAn orthopaedic surgeon is trained in the preservation, investigation and restoration of the form and function of the extremities, spine and associated…
    374J00000XDoulaDoulas work in a variety of settings and have been trained to provide physical, emotional, and informational support to a mother before, during, and j…
    163WC3500XCardiac Rehabilitation Registered NurseNursing Service Providers · Registered Nurse
    2472V0600XVeterinary TechnicianNone

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    A09Infectious gastroenteritis and colitis, unspecified
    B37.7Candidal sepsis
    B95.61Methicillin susceptible Staphylococcus aureus infection as the cause of diseases classified elsewhere
    C17.9Malignant neoplasm of small intestine, unspecified
    C18.9Malignant neoplasm of colon, unspecified
    C26.9Malignant neoplasm of ill-defined sites within the digestive system
    C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
    K25.4Chronic or unspecified gastric ulcer with hemorrhage
    K26.4Chronic or unspecified duodenal ulcer with hemorrhage
    K27.4Chronic or unspecified peptic ulcer, site unspecified, with hemorrhage

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 4

    10 rows

    PolicyPayerEffective Date
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01
    Celiac Disease TestingOscar Health2026-10-01
    Laboratory Testing for the Diagnosis of Inflammatory Bowel DiseaseOscar Health2026-10-01
    Percutaneous Electrical Nerve Field Stimulation (PENFS)Cigna2026-09-15
    Colorectal Cancer ScreeningBlue Cross Blue Shield - New Mexico2026-09-04

    Related Codes

    CPT-44100-SMALL-INTESTINE-CAPSULE-BIOPSY

    CPT 44100: Small Intestine Biopsy via Oral Capsule

    CPT-44110-OPEN-EXCISION-INTESTINAL-LESION-SINGLE-INCISION

    CPT 44110: Excision of Lesion(s) From Small or Large Intestine

    CPT-44111-INTESTINAL-LESION-EXCISION-MULTIPLE-INCISIONS

    CPT 44111: Excision of Intestinal Lesions via Multiple Incisions

    CPT-44120-SMALL-INTESTINE-RESECTION-PRIMARY-ANASTOMOSIS

    CPT 44120: Small Bowel Resection with Primary Anastomosis

    CPT-44121-ADDITIONAL-SMALL-INTESTINE-RESECTION-ANASTOMOSIS

    CPT 44121: Additional Small Intestine Resection and Anastomosis

    CPT-44125-SMALL-INTESTINE-RESECTION-WITH-STOMA-CREATION

    CPT 44125: Small Bowel Resection with Enterostomy

    CPT-44126-SMALL-BOWEL-RESECTION-CONGENITAL-ATRESIA-END-TO-END-ANASTOMOSIS

    CPT 44126: Small Bowel Resection for Intestinal Atresia with Anastomosis

    CPT-44127-SMALL-BOWEL-RESECTION-ANASTOMOSIS-INTESTINAL-ATRESIA

    CPT 44127: Resection and Anastomosis for Congenital Small-Bowel Atresia

    CPT-44128-SMALL-BOWEL-RESECTION-ANASTOMOSIS-CONGENITAL-ATRESIA

    CPT 44128: Resection of Small Intestine for Congenital Atresia

    CPT-44130-INTESTINAL-ANASTOMOSIS-BOWEL-RESECTION-ANASTOMOSIS

    CPT 44130: Intestinal Anastomosis, With or Without Stoma

    Showing 1–10 of 29

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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