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    v1.0.28
    OpenPayerBilling CodesTherapeutic, Preventive or Other InterventionsCPT cpt-4086f-aspirin-or-clopidogrel-prescription-cad-stroke-prevention
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    CPT 4086F: Aspirin or Clopidogrel Prescribed for CAD/Stroke Prevention

    CPT code 4086F documents that the provider prescribed or the patient is currently taking aspirin or clopidogrel for prevention or treatment of coronary artery disease, stroke, chest pain, or other vascular disease; service type: medication management / antiplatelet therapy prescription, typical site of service: outpatient clinic or ambulatory care setting.

    For related coverage guidance, see recent payer policy updates: Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA), Cardiovascular Disease Risk Assessment, Biomarkers for Myocardial Infarction and Chronic Heart Failure.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 62-year-old male with a history of coronary artery disease and prior percutaneous coronary intervention who presents for routine follow-up in primary care or cardiology clinic. The visit includes medication reconciliation, assessment of ischemic risk, and chronic secondary prevention counseling. The provider documents current use of antiplatelet therapy (aspirin or clopidogrel) and either prescribes, renews, or discontinues therapy based on clinical status, bleeding risk, and concurrent medications. The clinical workflow includes medication history verification, evaluation of indications (prior myocardial infarction, recent stent placement, ischemic stroke, or symptomatic coronary disease), review for contraindications (active bleeding, allergy), and documentation in the medical record that the patient is currently taking or has been prescribed aspirin or clopidogrel. Typical sites of service are outpatient primary care clinics, cardiology offices, and ambulatory surgical centers for pre-procedure medication management. The service is commonly coded when the provider explicitly documents antiplatelet therapy as part of chronic disease management or peri-procedural planning.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99213Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutesCommonly used for outpatient visits where antiplatelet therapy is prescribed, renewed, or reconciled as part of routine management.
    99214Office or other outpatient visit for the evaluation and management of an established patient, typically 25 minutesUsed when a more complex visit is required to assess ischemic and bleeding risk and adjust antiplatelet therapy.
    93000Electrocardiogram, routine ECG with at least 12 leads; with interpretation and reportOften performed alongside medication management when assessing ischemic symptoms or evaluating cardiac status before adjusting antiplatelet therapy.
    92928Percutaneous transcatheter placement of intracoronary stent(s), with coronary angioplasty when performed; single major coronary artery or branchInterventional procedure after which long-term antiplatelet therapy is typically prescribed and managed.
    36415Collection of venous blood by venipunctureCommonly performed when laboratory monitoring (e.g., hemoglobin, platelet count) is required before or during antiplatelet therapy.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    24Modifier 24 denotes an unrelated evaluation and management (E/M) service performed by the same physician or qualified healthcare professional during a postoperative global period. Per CPT guidance,…- Use modifier 24 when you report an evaluation and management (E/M) service performed by the same physician or same-specialty group during a procedure’s postoperative global period that is unrelated…
    57CPT® modifier -57 (“Decision for Surgery”) is appended to an Evaluation and Management (E/M) service when that encounter results in the initial decision to perform a major surgery (a procedure with a…- Use modifier 57 when an E/M service provided by the same provider (or same tax ID) on the day of or the day before a major surgical procedure (90‑day global period) results in the initial decision…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    95Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    207RG0300XGeriatric Medicine (Internal Medicine) PhysicianAn internist who has special knowledge of the aging process and special skills in the diagnostic, therapeutic, preventive and rehabilitative aspects o…
    207QG0300XGeriatric Medicine (Family Medicine) PhysicianA family medicine physician with special knowledge of the aging process and special skills in the diagnostic, therapeutic, preventive and rehabilitati…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    207RE0101XEndocrinology, Diabetes & Metabolism PhysicianAn internist who concentrates on disorders of the internal (endocrine) glands such as the thyroid and adrenal glands. This specialist also deals with …
    3416A0800XAir AmbulanceTransportation Services · Ambulance
    1835P1400XPain Management PharmacistA licensed pharmacist who has demonstrated specialized knowledge and skills, providing integrated, comprehensive, and accessible healthcare services t…

    Related ICD-10-CM Codes

    29 rows

    ICD-10-CM CodeDescription
    D50.9Iron deficiency anemia, unspecified
    E11.65Type 2 diabetes mellitus with hyperglycemia
    E78.5Hyperlipidemia, unspecified
    F17.210Nicotine dependence, cigarettes, uncomplicated
    G45.0Vertebro-basilar artery syndrome
    G45.9Transient cerebral ischemic attack, unspecified
    I20.9Angina pectoris, unspecified
    I21.9Acute myocardial infarction, unspecified
    I22.9Subsequent ST elevation (STEMI) myocardial infarction of unspecified site
    I25.10Atherosclerotic heart disease of native coronary artery without angina pectoris

    Showing 1–10 of 29

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    6 rows

    PolicyPayerEffective Date
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Cardiovascular Disease Risk Assessmentblue cross blue shield - louisiana2026-09-15
    Cardiovascular Disease Risk AssessmentBlue Cross Blue Shield - New Mexico2026-09-04

    Related Codes

    CPT-4000F-ASTHMA-TOBACCO-EXPOSURE-COUNSELING

    CPT 4000F: Asthma-Related Tobacco Exposure and Counseling

    CPT-4001F-ASTHMA-TOBACCO-EXPOSURE-SMOKING-CESSATION-MEDICATION-DISCUSSION

    CPT 4001F: Asthma Patient Tobacco Exposure and Smoking Cessation Discussion

    CPT-4003F-UNDEFINED-MEASURE

    CPT 4003F: Preventive Counseling or Risk-Factor Intervention

    CPT-4004F-TOBACCO-USE-SCREENING-AND-CESSATION-OFFER-ADULT

    CPT 4004F: Tobacco Use Screening and Offer of Cessation for Adults

    CPT-4005F-UNKNOWN-SERVICE

    CPT 4005F: No Summary found

    CPT-4008F-UNKNOWN-SERVICE

    CPT 4008F: No Summary available

    CPT-4010F-ACE-INHIBITOR-ARB-THERAPY-DOCUMENTATION

    CPT 4010F: ACE Inhibitor or ARB Therapy Prescribed or Current

    CPT-4011F-ANTIPLATELET-THERAPY-PRESCRIPTION-MANAGEMENT

    CPT 4011F: Prescription for Antiplatelet Therapy

    CPT-4012F-UNCATEGORIZED-PROCEDURE

    CPT 4012F: No Summary Available

    CPT-4013F-STATIN-THERAPY-PRESCRIPTION-OR-CURRENT-USE

    CPT 4013F: Statin Therapy Prescription or Current Use

    Showing 1–10 of 175

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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