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    v1.0.28
    OpenPayerBilling CodesTherapeutic, Preventive or Other InterventionsCPT cpt-4044f-perioperative-vte-prophylaxis-order
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    CPT 4044F: Order for Perioperative VTE Prophylaxis

    CPT code 4044F documents that the provider ordered administration of prophylactic therapy for venous thromboembolism within 24 hours before or within 24 hours after a surgical procedure; service type: perioperative prophylaxis order provided in the inpatient or outpatient surgical setting (preoperative or immediate postoperative period).

    For related coverage guidance, see recent payer policy updates: Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA), Cardiovascular Disease Risk Assessment, Biomarkers for Myocardial Infarction and Chronic Heart Failure.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 62-year-old male scheduled for elective total hip arthroplasty. He presents to the preoperative clinic the day before surgery for a history and physical and medication reconciliation. The surgeon documents an order for pharmacologic prophylaxis against venous thromboembolism (VTE), specifying agent (e.g., low molecular weight heparin or a direct oral anticoagulant), dose, timing, and anticipated duration. The order is placed within 24 hours before the surgical procedure. Perioperative nursing and pharmacy confirm the order, and prophylaxis administration is recorded in the electronic medical record. Postoperatively, the provider again documents or adjusts the VTE prophylaxis plan within 24 hours after surgery based on bleeding risk, renal function, and mobility status. This service supports quality monitoring and measure reporting that captures timely ordering of VTE prophylaxis around a surgical episode.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99203Office or Other Outpatient Visit for the Evaluation and Management of a New Patient, moderate complexityPreoperative clinic visit where the VTE prophylaxis order may be documented within 24 hours before surgery.
    99232Subsequent Hospital Care, typically 25 minutes per dayPostoperative inpatient visit during which the provider documents or modifies VTE prophylaxis within 24 hours after surgery.
    36591Collection of blood for home testing by venipuncture; adultsPreoperative labs for renal function or coagulation studies that inform prophylaxis agent selection.
    90471Immunization administration (single or first component)Not directly related but example of a separately reportable medication administration service; prophylactic medication administrations are recorded in medication administration records rather than billed as immunizations.
    99195Moderate sedation services for procedures performed by the same physician or other qualified health care professional in facility (if applicable)Sedation/anesthesia services during surgery in which perioperative orders including prophylaxis are managed.

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    24Modifier 24 denotes an unrelated evaluation and management (E/M) service performed by the same physician or qualified healthcare professional during a postoperative global period. Per CPT guidance,…- Use modifier 24 when you report an evaluation and management (E/M) service performed by the same physician or same-specialty group during a procedure’s postoperative global period that is unrelated…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    92Modifier 92 (Alternative Laboratory Platform Testing) is used when laboratory tests are performed with single‑use, disposable, portable kits or transportable instruments. The AMA defines it for tests…- Use modifier 92 when a laboratory test is performed using a single‑use, disposable analytical device or kit (an alternative laboratory platform) that is portable and may be taken to or near the…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207RA0000XAdolescent Medicine (Internal Medicine) PhysicianAn internist who specializes in adolescent medicine is a multi-disciplinary healthcare specialist trained in the unique physical, psychological and so…
    363A00000XPhysician AssistantA physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
    174M00000XVeterinarianA doctor of veterinary medicine, trained and authorized to practice veterinarian medicine and surgery.
    2084N0402XNeurology with Special Qualifications in Child Neurology PhysicianA Child Neurologist specializes in neurology with special skills in diagnosis and treatment of neurologic disorders of the neonatal period, infancy, e…
    207RH0000XHematology (Internal Medicine) PhysicianAn internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, cl…
    261QU0200XUrgent Care Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    6 rows

    PolicyPayerEffective Date
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Cardiovascular Disease Risk Assessmentblue cross blue shield - louisiana2026-09-15
    Cardiovascular Disease Risk AssessmentBlue Cross Blue Shield - New Mexico2026-09-04

    Related Codes

    CPT-4000F-ASTHMA-TOBACCO-EXPOSURE-COUNSELING

    CPT 4000F: Asthma-Related Tobacco Exposure and Counseling

    CPT-4001F-ASTHMA-TOBACCO-EXPOSURE-SMOKING-CESSATION-MEDICATION-DISCUSSION

    CPT 4001F: Asthma Patient Tobacco Exposure and Smoking Cessation Discussion

    CPT-4003F-UNDEFINED-MEASURE

    CPT 4003F: Preventive Counseling or Risk-Factor Intervention

    CPT-4004F-TOBACCO-USE-SCREENING-AND-CESSATION-OFFER-ADULT

    CPT 4004F: Tobacco Use Screening and Offer of Cessation for Adults

    CPT-4005F-UNKNOWN-SERVICE

    CPT 4005F: No Summary found

    CPT-4008F-UNKNOWN-SERVICE

    CPT 4008F: No Summary available

    CPT-4010F-ACE-INHIBITOR-ARB-THERAPY-DOCUMENTATION

    CPT 4010F: ACE Inhibitor or ARB Therapy Prescribed or Current

    CPT-4011F-ANTIPLATELET-THERAPY-PRESCRIPTION-MANAGEMENT

    CPT 4011F: Prescription for Antiplatelet Therapy

    CPT-4012F-UNCATEGORIZED-PROCEDURE

    CPT 4012F: No Summary Available

    CPT-4013F-STATIN-THERAPY-PRESCRIPTION-OR-CURRENT-USE

    CPT 4013F: Statin Therapy Prescription or Current Use

    Showing 1–10 of 175

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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