CPT 4011F: Prescription for Antiplatelet Therapy

CPT code 4011F documents that a provider prescribed an antiplatelet medication that prevents platelets from sticking together to reduce the risk of myocardial infarction and stroke; this represents a prescription for antiplatelet therapy typically provided in an outpatient clinic or primary care setting as part of cardiovascular disease management and secondary prevention.

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CPT 4011F: Prescription for Antiplatelet Therapy

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Clinical & Coding Specifications

Clinical Context

A typical patient is an adult with established atherosclerotic cardiovascular disease or multiple cardiovascular risk factors who is seen in outpatient primary care or cardiology clinic for secondary prevention counseling and medication management. The clinician assesses history of myocardial infarction, ischemic stroke, transient ischemic attack, coronary artery stenting, peripheral arterial disease, or high-risk coronary anatomy, and determines the need to initiate or continue an antiplatelet agent (for example aspirin, clopidogrel, ticagrelor, prasugrel). The workflow includes medication reconciliation, review of bleeding risk and allergies, discussion of indication and expected duration, documentation of informed consent when applicable, and e-prescribing or handwritten prescription generation. Typical site of service is outpatient clinic (primary care or cardiology), ambulatory surgical center when prescribed peri-procedurally, or hospital inpatient medical service when started during admission for acute coronary syndrome or stroke. The common patient scenario: a 68-year-old man with prior myocardial infarction and coronary stent presents for follow-up; clinician documents ongoing need for antiplatelet therapy and prescribes a P2Y12 inhibitor to reduce risk of recurrent myocardial infarction and stroke, with counseling on adherence and bleeding precautions.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`99213`	Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutes	Routine follow-up visit during which antiplatelet therapy is assessed and prescribed
`99214`	Office or other outpatient visit for the evaluation and management of an established patient, typically 25 minutes	Detailed management visit for medication initiation or complex risk/benefit discussion
`92928`	Percutaneous transcatheter placement of intracoronary stent(s), with coronary angioplasty when performed; single major coronary artery	Antiplatelet agents are commonly prescribed after coronary stent placement to prevent stent thrombosis
`93651`	Intracardiac electrophysiological catheter mapping and ablation	Antiplatelet therapy may be part of periprocedural management for certain patients undergoing cardiac procedures

Related Modifiers

5 rows

Modifier	Description	When to Use
24	Modifier 24 denotes an unrelated evaluation and management (E/M) service performed by the same physician or qualified healthcare professional during a postoperative global period. Per CPT guidance,…	- Use modifier 24 when you report an evaluation and management (E/M) service performed by the same physician or same-specialty group during a procedure’s postoperative global period that is unrelated…
P2	Modifier P2 denotes an ASA Physical Status II — a patient with mild systemic disease. Per AMA/AAPC, examples include well-controlled hypertension or diabetes, mild obesity (BMI 30–40), current smoker…	- When to use: Append modifier -P2 to anesthesia CPT codes (00100–01999) when the anesthesia provider documents the patient has mild systemic disease (ASA Physical Status II) — for example…
51	Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…	- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
33	Modifier 33 was created by the American Medical Association in response to the Affordable Care Act to identify services provided for preventive intent. It is appended to CPT/HCPCS codes that could be…	- Use modifier -33 when a CPT/HCPCS service that can be billed as either preventive or diagnostic/treatment is provided with preventive intent and aligns with USPSTF A or B recommendations or other…
57	CPT® modifier -57 (“Decision for Surgery”) is appended to an Evaluation and Management (E/M) service when that encounter results in the initial decision to perform a major surgery (a procedure with a…	- Use modifier 57 when an E/M service provided by the same provider (or same tax ID) on the day of or the day before a major surgical procedure (90‑day global period) results in the initial decision…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207RC0000X	Cardiovascular Disease Physician	An internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
208D00000X	General Practice Physician	A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
2085R0001X	Radiation Oncology Physician	A radiologist who deals with the therapeutic applications of radiant energy and its modifiers and the study and management of disease, especially mali…
235Z00000X	Speech-Language Pathologist	The speech-language pathologist is the professional who engages in clinical services, prevention, advocacy, education, administration, and research in…
207VX0201X	Gynecologic Oncology Physician	An obstetrician/gynecologist who provides consultation and comprehensive management of patients with gynecologic cancer, including those diagnostic an…
207YX0901X	Otology & Neurotology Physician	An otolaryngologist who treats diseases of the ear and temporal bone, including disorders of hearing and balance. The additional training in otology a…
2080P0203X	Pediatric Critical Care Medicine Physician	A pediatrician expert in advanced life support for children from the term or near-term neonate to the adolescent. This competence extends to the criti…
207N00000X	Dermatology Physician	A dermatologist is trained to diagnose and treat pediatric and adult patients with benign and malignant disorders of the skin, mouth, external genital…

CPT 4000F: Asthma-Related Tobacco Exposure and Counseling

CPT-4001F-ASTHMA-TOBACCO-EXPOSURE-SMOKING-CESSATION-MEDICATION-DISCUSSION

CPT 4001F: Asthma Patient Tobacco Exposure and Smoking Cessation Discussion

CPT-4003F-UNDEFINED-MEASURE

CPT 4003F: Preventive Counseling or Risk-Factor Intervention

CPT-4004F-TOBACCO-USE-SCREENING-AND-CESSATION-OFFER-ADULT

CPT 4004F: Tobacco Use Screening and Offer of Cessation for Adults

CPT-4005F-UNKNOWN-SERVICE

CPT 4005F: No Summary found

CPT-4008F-UNKNOWN-SERVICE

CPT 4008F: No Summary available

CPT-4010F-ACE-INHIBITOR-ARB-THERAPY-DOCUMENTATION

CPT 4010F: ACE Inhibitor or ARB Therapy Prescribed or Current

CPT-4012F-UNCATEGORIZED-PROCEDURE

CPT 4012F: No Summary Available

CPT-4013F-STATIN-THERAPY-PRESCRIPTION-OR-CURRENT-USE

CPT 4013F: Statin Therapy Prescription or Current Use

CPT-4014F-PERFORMANCE-MEASURE-QUALITY-REPORTING

CPT 4014F: Unspecified Procedure — No Summary Available

Showing 1–10 of 175

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`99213`	Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutes	Routine follow-up visit during which antiplatelet therapy is assessed and prescribed
`99214`	Office or other outpatient visit for the evaluation and management of an established patient, typically 25 minutes	Detailed management visit for medication initiation or complex risk/benefit discussion
`92928`	Percutaneous transcatheter placement of intracoronary stent(s), with coronary angioplasty when performed; single major coronary artery	Antiplatelet agents are commonly prescribed after coronary stent placement to prevent stent thrombosis
`93651`	Intracardiac electrophysiological catheter mapping and ablation	Antiplatelet therapy may be part of periprocedural management for certain patients undergoing cardiac procedures

Related Modifiers

5 rows

Modifier	Description	When to Use
24	Modifier 24 denotes an unrelated evaluation and management (E/M) service performed by the same physician or qualified healthcare professional during a postoperative global period. Per CPT guidance,…	- Use modifier 24 when you report an evaluation and management (E/M) service performed by the same physician or same-specialty group during a procedure’s postoperative global period that is unrelated…
P2	Modifier P2 denotes an ASA Physical Status II — a patient with mild systemic disease. Per AMA/AAPC, examples include well-controlled hypertension or diabetes, mild obesity (BMI 30–40), current smoker…	- When to use: Append modifier -P2 to anesthesia CPT codes (00100–01999) when the anesthesia provider documents the patient has mild systemic disease (ASA Physical Status II) — for example…
51	Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…	- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
33	Modifier 33 was created by the American Medical Association in response to the Affordable Care Act to identify services provided for preventive intent. It is appended to CPT/HCPCS codes that could be…	- Use modifier -33 when a CPT/HCPCS service that can be billed as either preventive or diagnostic/treatment is provided with preventive intent and aligns with USPSTF A or B recommendations or other…
57	CPT® modifier -57 (“Decision for Surgery”) is appended to an Evaluation and Management (E/M) service when that encounter results in the initial decision to perform a major surgery (a procedure with a…	- Use modifier 57 when an E/M service provided by the same provider (or same tax ID) on the day of or the day before a major surgical procedure (90‑day global period) results in the initial decision…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207RC0000X	Cardiovascular Disease Physician	An internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
208D00000X	General Practice Physician	A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
2085R0001X	Radiation Oncology Physician	A radiologist who deals with the therapeutic applications of radiant energy and its modifiers and the study and management of disease, especially mali…
235Z00000X	Speech-Language Pathologist	The speech-language pathologist is the professional who engages in clinical services, prevention, advocacy, education, administration, and research in…
207VX0201X	Gynecologic Oncology Physician	An obstetrician/gynecologist who provides consultation and comprehensive management of patients with gynecologic cancer, including those diagnostic an…
207YX0901X	Otology & Neurotology Physician	An otolaryngologist who treats diseases of the ear and temporal bone, including disorders of hearing and balance. The additional training in otology a…
2080P0203X	Pediatric Critical Care Medicine Physician	A pediatrician expert in advanced life support for children from the term or near-term neonate to the adolescent. This competence extends to the criti…
207N00000X	Dermatology Physician	A dermatologist is trained to diagnose and treat pediatric and adult patients with benign and malignant disorders of the skin, mouth, external genital…

CPT 4000F: Asthma-Related Tobacco Exposure and Counseling

CPT-4001F-ASTHMA-TOBACCO-EXPOSURE-SMOKING-CESSATION-MEDICATION-DISCUSSION

CPT 4001F: Asthma Patient Tobacco Exposure and Smoking Cessation Discussion

CPT-4003F-UNDEFINED-MEASURE

CPT 4003F: Preventive Counseling or Risk-Factor Intervention

CPT-4004F-TOBACCO-USE-SCREENING-AND-CESSATION-OFFER-ADULT

CPT 4004F: Tobacco Use Screening and Offer of Cessation for Adults

CPT-4005F-UNKNOWN-SERVICE

CPT 4005F: No Summary found

CPT-4008F-UNKNOWN-SERVICE

CPT 4008F: No Summary available

CPT-4010F-ACE-INHIBITOR-ARB-THERAPY-DOCUMENTATION

CPT 4010F: ACE Inhibitor or ARB Therapy Prescribed or Current

CPT-4012F-UNCATEGORIZED-PROCEDURE

CPT 4012F: No Summary Available

CPT-4013F-STATIN-THERAPY-PRESCRIPTION-OR-CURRENT-USE

CPT 4013F: Statin Therapy Prescription or Current Use

CPT-4014F-PERFORMANCE-MEASURE-QUALITY-REPORTING

CPT 4014F: Unspecified Procedure — No Summary Available

Showing 1–10 of 175

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

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CPT 4011F: Prescription for Antiplatelet Therapy

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CPT 4011F: Prescription for Antiplatelet Therapy

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

References

CPT 4011F: Prescription for Antiplatelet Therapy

Sign up for cpt 4011F policy alerts

CPT 4011F: Prescription for Antiplatelet Therapy

Sign up for cpt 4011F policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What clinical action does CPT 4011F represent?

Where is CPT 4011F typically reported (site of service)?

What related CPT codes should be considered when documenting the visit that results in a 4011F prescription?

Which modifier and provider taxonomies are associated with CPT 4011F?

Do payers recognize CPT 4011F and does the page provide reimbursement rates?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What clinical action does CPT 4011F represent?

Where is CPT 4011F typically reported (site of service)?

What related CPT codes should be considered when documenting the visit that results in a 4011F prescription?

Which modifier and provider taxonomies are associated with CPT 4011F?

Do payers recognize CPT 4011F and does the page provide reimbursement rates?

References