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    v1.0.30
    OpenPayerBilling CodesTherapeutic, Preventive or Other InterventionsCPT cpt-4011f-antiplatelet-therapy-prescription-management
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    CPT 4011F: Prescription for Antiplatelet Therapy

    CPT code 4011F documents that a provider prescribed an antiplatelet medication that prevents platelets from sticking together to reduce the risk of myocardial infarction and stroke; this represents a prescription for antiplatelet therapy typically provided in an outpatient clinic or primary care setting as part of cardiovascular disease management and secondary prevention.

    For related coverage guidance, see recent payer policy updates: Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood Pressure, Cardiology - Ivabradine, Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA).

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with established atherosclerotic cardiovascular disease or multiple cardiovascular risk factors who is seen in outpatient primary care or cardiology clinic for secondary prevention counseling and medication management. The clinician assesses history of myocardial infarction, ischemic stroke, transient ischemic attack, coronary artery stenting, peripheral arterial disease, or high-risk coronary anatomy, and determines the need to initiate or continue an antiplatelet agent (for example aspirin, clopidogrel, ticagrelor, prasugrel). The workflow includes medication reconciliation, review of bleeding risk and allergies, discussion of indication and expected duration, documentation of informed consent when applicable, and e-prescribing or handwritten prescription generation. Typical site of service is outpatient clinic (primary care or cardiology), ambulatory surgical center when prescribed peri-procedurally, or hospital inpatient medical service when started during admission for acute coronary syndrome or stroke. The common patient scenario: a 68-year-old man with prior myocardial infarction and coronary stent presents for follow-up; clinician documents ongoing need for antiplatelet therapy and prescribes a P2Y12 inhibitor to reduce risk of recurrent myocardial infarction and stroke, with counseling on adherence and bleeding precautions.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99213Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutesRoutine follow-up visit during which antiplatelet therapy is assessed and prescribed
    99214Office or other outpatient visit for the evaluation and management of an established patient, typically 25 minutesDetailed management visit for medication initiation or complex risk/benefit discussion
    92928Percutaneous transcatheter placement of intracoronary stent(s), with coronary angioplasty when performed; single major coronary arteryAntiplatelet agents are commonly prescribed after coronary stent placement to prevent stent thrombosis
    93651Intracardiac electrophysiological catheter mapping and ablationAntiplatelet therapy may be part of periprocedural management for certain patients undergoing cardiac procedures

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    24Modifier 24 denotes an unrelated evaluation and management (E/M) service performed by the same physician or qualified healthcare professional during a postoperative global period. Per CPT guidance,…- Use modifier 24 when you report an evaluation and management (E/M) service performed by the same physician or same-specialty group during a procedure’s postoperative global period that is unrelated…
    P2Modifier P2 denotes an ASA Physical Status II — a patient with mild systemic disease. Per AMA/AAPC, examples include well-controlled hypertension or diabetes, mild obesity (BMI 30–40), current smoker…- When to use: Append modifier -P2 to anesthesia CPT codes (00100–01999) when the anesthesia provider documents the patient has mild systemic disease (ASA Physical Status II) — for example…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    33Modifier 33 was created by the American Medical Association in response to the Affordable Care Act to identify services provided for preventive intent. It is appended to CPT/HCPCS codes that could be…- Use modifier -33 when a CPT/HCPCS service that can be billed as either preventive or diagnostic/treatment is provided with preventive intent and aligns with USPSTF A or B recommendations or other…
    57CPT® modifier -57 (“Decision for Surgery”) is appended to an Evaluation and Management (E/M) service when that encounter results in the initial decision to perform a major surgery (a procedure with a…- Use modifier 57 when an E/M service provided by the same provider (or same tax ID) on the day of or the day before a major surgical procedure (90‑day global period) results in the initial decision…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    208D00000X
    2085R0001X
    235Z00000X
    207VX0201X
    207YX0901X
    2080P0203X
    207N00000X

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood PressureBluecross Idaho2026-11-01
    Cardiology - IvabradineCigna2026-10-15
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Percutaneous Ventricular Assist DeviceUnitedHealthcare2026-10-01
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Left Atrial Appendage Closure Devicesexcellus_health_plan_inc2026-09-17
    Left Atrial Appendage Closure Devicesuniverahealthcare2026-09-17
    Cardiac Omnibus CodesCigna2026-09-15

    Related Codes

    CPT-4000F-ASTHMA-TOBACCO-EXPOSURE-COUNSELING

    CPT 4000F: Asthma-Related Tobacco Exposure and Counseling

    CPT-4001F-ASTHMA-TOBACCO-EXPOSURE-SMOKING-CESSATION-MEDICATION-DISCUSSION

    CPT 4001F: Asthma Patient Tobacco Exposure and Smoking Cessation Discussion

    CPT-4003F-UNDEFINED-MEASURE

    CPT 4003F: Preventive Counseling or Risk-Factor Intervention

    CPT-4004F-TOBACCO-USE-SCREENING-AND-CESSATION-OFFER-ADULT

    CPT 4004F: Tobacco Use Screening and Offer of Cessation for Adults

    CPT-4005F-UNKNOWN-SERVICE

    CPT 4005F: No Summary found

    CPT-4008F-UNKNOWN-SERVICE

    CPT 4008F: No Summary available

    CPT-4010F-ACE-INHIBITOR-ARB-THERAPY-DOCUMENTATION

    CPT 4010F: ACE Inhibitor or ARB Therapy Prescribed or Current

    CPT-4012F-UNCATEGORIZED-PROCEDURE

    CPT 4012F: No Summary Available

    CPT-4013F-STATIN-THERAPY-PRESCRIPTION-OR-CURRENT-USE

    CPT 4013F: Statin Therapy Prescription or Current Use

    CPT-4014F-PERFORMANCE-MEASURE-QUALITY-REPORTING

    CPT 4014F: Unspecified Procedure — No Summary Available

    Showing 1–10 of 175

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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