CPT code 36514 designates therapeutic plasma exchange (apheresis) for removal of plasma, a targeted hematologic procedure used to treat a range of immune-mediated and metabolic conditions by extracting plasma and returning formed blood elements. Nationally, this code is significant for hospitals and specialty infusion centers because it captures a high-resource service that requires specialized equipment, trained staff, and defined care settings.

Key payers in typical coverage analyses include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of the code’s clinical context and service settings, typical payer coverage considerations, and what to expect in billing and claim reporting. The publication also summarizes benchmark topics such as utilization drivers, site-of-service implications, and documentation elements commonly reviewed by payers.

This summary is intended to orient clinicians, billing professionals, and policy analysts to the core meaning and health-system implications of CPT code 36514, explain where the procedure is typically performed, and identify the primary payer stakeholders referenced in coverage discussions. Data not available in the input are noted where applicable in the full publication.