CPT code 33465 designates open surgical replacement of the tricuspid valve performed with the patient on cardiopulmonary bypass. This code captures a major cardiac surgical intervention for severe tricuspid valve disease, including regurgitation or stenosis not amenable to repair. Nationally, tricuspid valve replacement represents a focused but clinically significant portion of cardiac surgical volume due to its complexity, resource intensity, and implications for perioperative care.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise briefing on clinical context, typical site-of-service considerations, and the elements that define billing for an open tricuspid valve replacement. The publication also summarizes common billing modifiers and payer coverage patterns where available, alongside coding neighbors and service-line placement to assist revenue cycle and clinical teams in mapping procedures to inpatient surgical workflows.

This overview is intended for national audiences involved in coding, clinical operations, and payer contracting. It explains what the code represents, where the service is usually delivered, and what operational and policy topics are most relevant for teams managing high-acuity cardiac surgery cases.