CPT 33405: Aortic Valve Replacement, Open with CPB
Medicare pays $2135 and commercial payers pay $2850 on average nationally for this procedure.
CPT code 33405 describes open surgical replacement of the aortic valve with a non-homograft, non-ventless prosthetic valve performed with the patient on cardiopulmonary bypass; this is a cardiac surgical procedure (aortic valve replacement) typically performed in an inpatient operating room or cardiothoracic surgical suite to restore effective systemic blood flow.
For related coverage guidance, see recent payer policy updates: Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders, Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders, Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders.
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National Reimbursement Benchmarks
National commercial averages sit above Medicare for CPT 33405: BUCA’s mean of $2,849.70 exceeds Medicare’s mean of $2,135.50 by $714.20, indicating higher commercial pricing for this procedure versus the Medicare baseline. Blue Cross Blue Shield ($2,468.10 mean), Aetna ($1,854.00 mean), Cigna ($3,707.00 mean) and UnitedHealth Group ($4,132.60 mean) span a wide commercial cost spectrum, with UnitedHealth Group at the high end and Aetna at the low end of those listed.
Dispersion measured as the interquartile range (P75–P25) varies notably: Aetna’s IQR is $2,247.90, Blue Cross Blue Shield’s is $1,595.70, BUCA’s is $1,990.60, Cigna’s is $2,410.80, and UnitedHealth Group’s is $2,478.50. Blue Cross Blue Shield is the tightest payer by IQR, while UnitedHealth Group and Cigna exhibit the widest 25–75 spreads, signaling greater rate variability among those payers.