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    OpenPayerBilling CodesIncisional Electrophysiologic Procedures on the Heart and PericardiumCPT cpt-33268-left-atrial-appendage-exclusion-open-surgery
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    CPT 33268: Left Atrial Appendage Exclusion at Sternotomy/Thoracotomy

    Medicare pays $117 on average nationally for this procedure.

    CPT code 33268 describes surgical exclusion (for example, excision) of the left atrial appendage performed at the same operative session as a primary procedure that requires a sternotomy or thoracotomy; the service is a cardiac surgical adjunct typically delivered in an inpatient operating room or other surgical suite during open-chest cardiac procedures where left atrial appendage management is indicated.

    For related coverage guidance, see recent payer policy updates: Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA), Cardiovascular Disease Risk Assessment, Biomarkers for Myocardial Infarction and Chronic Heart Failure.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 72-year-old man with persistent atrial fibrillation and left ventricular dysfunction is scheduled for surgical coronary artery bypass grafting (CABG) via median sternotomy. During the same operative session, the cardiothoracic surgeon performs exclusion of the left atrial appendage to reduce future thromboembolic risk. The intraoperative workflow includes general endotracheal anesthesia, median sternotomy, cardiopulmonary bypass as indicated, myocardial revascularization, inspection of the left atrial appendage, and surgical exclusion by excision or oversewing. Hemostasis is confirmed, chest tubes placed, and the sternum closed. Postoperative documentation includes indication for left atrial appendage exclusion, method used (excision, suture, or device), confirmation that the work was performed at the same session as the primary sternotomy procedure, estimated blood loss, complications, and any additional procedures or modifiers applied for billing.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    33510Revascularization, coronary artery, bypass, vein only; single coronary venous graftCommon primary procedure performed via median sternotomy during which left atrial appendage exclusion may be performed concurrently.
    33533Coronary artery bypass, using arterial graft(s); single arterial graftAlternative or additional CABG codes performed in the same session with possible LAA exclusion.
    33240Insertion of temporary transvenous pacemakerMay be performed before or after cardiac surgery when arrhythmia management is required perioperatively.
    33208Insertion of permanent pacemaker, epicardial (separate procedure)Sometimes performed concomitantly during open cardiac surgery for rhythm control.
    33405Repair of cardiac septal defect under direct visionOther open cardiac procedures that may occur in the same sternotomy session where LAA exclusion can be an adjunct.
    33426Excision of left atrial myxoma or massOther left atrial procedures where LAA management may be addressed during the same operation.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    207RP1001XPulmonary Disease PhysicianAn internist who treats diseases of the lungs and airways. The pulmonologist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational an…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    207R00000XInternal Medicine PhysicianA physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
    2084S0010XSports Medicine (Psychiatry & Neurology) PhysicianA psychiatrist or neurologist who specializes in the diagnosis and treatment of sports related conditions and injuries.
    364SH0200XHome Health Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
    163WW0101XAmbulatory Women's Health Care Registered NurseNursing Service Providers · Registered Nurse

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Cardiovascular Disease Risk Assessmentblue cross blue shield - louisiana2026-09-15
    Cardiovascular Disease Risk AssessmentBlue Cross Blue Shield - New Mexico2026-09-04
    Computed Tomography to Detect Coronary Artery CalcificationBluecross Idaho2026-09-01
    Intracoronary Drug Delivery Balloon ProceduresBlue Cross Blue Shield - Rhode Island2026-09-01
    Cardiac Imaging Guidelinesevicore2026-09-01
    Percutaneous Left Atrial Appendage Closure Device for Stroke PreventionAmbetter Georgia2026-08-26

    Related Codes

    CPT-33250-CARDIAC-ARRHYTHMIA-ABLATION-NO-BYPASS

    CPT 33250: Catheter Ablation of Supraventricular Focus Without Bypass

    CPT-33251-CARDIAC-ABLATION-WITH-CARDIOPULMONARY-BYPASS

    CPT 33251: Catheter Ablation With Cardiopulmonary Bypass

    CPT-33254-ATRIAL-ABLATION-AND-ATRIAL-RECONSTRUCTION

    CPT 33254: Atrial Tissue Destruction with Atrial Reconstruction

    CPT-33255-ATRIAL-ABLATION-AND-ATRIAL-RECONSTRUCTION-OFF-PUMP

    CPT 33255: Atrial Tissue Ablation with Left and Right Atrial Reconstruction

    CPT-33256-ATRIAL-ABLATION-ATRIAL-RECONSTRUCTION

    CPT 33256: Maze Procedure with Atrial Reconstruction

    CPT-33257-ATRIAL-ABLATION-AND-RECONSTRUCTION-ADD-ON

    CPT 33257: Atrial Tissue Destruction with Atrial Reconstruction

    CPT-33258-ATRIAL-FIBRILLATION-ATRIAL-RECONSTRUCTION-NO-BYPASS

    CPT 33258: Atrial Ablation with Extensive Atrial Reconstruction (No CPB)

    CPT-33259-EXTENSIVE-ATRIAL-ABLATION-AND-RECONSTRUCTION

    CPT 33259: Extensive Atrial Destruction and Reconstruction (Maze Procedure)

    CPT-33261-CARDIAC-VENTRICULAR-ABLATION-CARDIOPULMONARY-BYPASS

    CPT 33261: Ventricular Ablation with Cardiopulmonary Bypass

    CPT-33264-IMPLANTABLE-DEFIBRILLATOR-PULSE-GENERATOR-REPLACEMENT-THREE-CHAMBER

    CPT 33264: Replacement of Implantable Defibrillator Pulse Generator, Multichamber

    Showing 1–10 of 11

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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