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    v1.0.31
    OpenPayerBilling CodesExcision Procedures of Cardiac TumorCPT cpt-33130-pericardial-tumor-excision
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    CPT 33130: Pericardial Tumor Excision

    Medicare pays $1320 on average nationally for this procedure.

    CPT code 33130 describes surgical excision of a tumor originating in the pericardium, representing an operative procedure to remove pericardial masses; the service is a surgical pericardial tumor resection typically performed in an inpatient or operating room setting by cardiothoracic surgeons and documented as an open thoracic procedure for tumor removal from the pericardial sac.

    For related coverage guidance, see recent payer policy updates: Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult referred to cardiothoracic surgery after imaging identifies a symptomatic pericardial mass or pericardial tumor causing constriction, effusion with tamponade physiology, or chest pain and dyspnea. Preoperative workup includes transthoracic and/or transesophageal echocardiography, chest CT or cardiac MRI to define tumor size and location, cardiac catheterization if coronary anatomy is needed, and routine labs including coagulation. The procedure, coded as 33130, is performed in an operating room or cardiac surgery suite under general endotracheal anesthesia. Intraoperative monitoring includes arterial line, central venous access, transesophageal echocardiography, and cardiopulmonary bypass availability if resection is technically complex or tumor invades myocardium. The surgeon exposes the pericardium via median sternotomy or thoracotomy, performs pericardiectomy as needed, and excises the tumor with attention to hemostasis and preservation of cardiac structures. Resected tissue is sent for pathology. Postoperative care occurs in a cardiac recovery unit or intensive care unit with monitoring for tamponade, arrhythmia, bleeding, infection, and hemodynamic instability. Typical hospital stay ranges from 2–7 days depending on complexity and comorbidities. Billing reflects the operative removal of a pericardial tumor and may include concurrent services such as pericardial window or biopsy when reported appropriately with correct modifiers.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    33210Repair of cardiac or pericardial fistula; direct closureMay be performed if tumor resection results in fistula formation requiring repair during the same operative session
    33010Pericardiocentesis, including imaging guidance, when performed as a separate procedurePerformed preoperatively or emergently for tamponade prior to definitive tumor resection
    33025Pericardial window, subxiphoid or other approachMay be performed if a pericardial window is required for drainage or biopsy in conjunction with or prior to tumor removal
    88304Surgical pathology, gross and microscopic examinationUsed for pathology processing and interpretation of the resected pericardial tumor specimen
    33999Unlisted procedure, cardiac; if additional cardiac reconstruction is not described by existing codesApplied when unusual reconstruction beyond standard resection is required and no specific code exists

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    208000000X
    208D00000X
    207P00000X
    163WU0100X
    261QE0002X
    1223D0004X
    261QA0900X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    C38.2Malignant neoplasm of posterior mediastinum
    D15.1Benign neoplasm of heart
    D48.0Neoplasm of uncertain behavior of bone and articular cartilage
    I30.0Acute nonspecific idiopathic pericarditis
    I30.1Infective pericarditis
    I30.9Acute pericarditis, unspecified
    I31.0Chronic adhesive pericarditis
    I31.2Hemopericardium, not elsewhere classified
    I31.39Other pericardial effusion (noninflammatory)
    I31.8Other specified diseases of pericardium

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Cardiology1 / 2

    10 rows

    PolicyPayerEffective Date
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Left Atrial Appendage Occlusion, Closurearkansas_blue_cross_blue_shield2027-02-01
    Percutaneous Left Atrial Appendage Closure - Medical PolicyHealth-New-England2027-02-01
    Transcatheter Mitral Valve Repair Medical PolicyHealth-New-England2027-02-01
    Cardiac Electrophysiological (EP) Studies and Cardiac Ablation of Abnormal Electrical RhythmsCigna2027-01-15
    IvabradineCigna2026-11-15
    Tilt Table TestingCigna2026-11-15
    Cardiac Contractility Modulation for Heart FailureProvidence Health Plan2026-11-01

    Related Codes

    CPT-33120-CARDIAC-TUMOR-EXCISION-CARDIOPULMONARY-BYPASS

    CPT 33120: Excision of Intracardiac Tumor with Cardiopulmonary Bypass

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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