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    OpenPayerBilling CodesArthrodesis Procedures on the Femur (Thigh Region) and Knee JointCPT cpt-27580-knee-arthrodesis-fusion
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    CPT 27580: Knee Arthrodesis (Fusion)

    Medicare pays $1377 on average nationally for this procedure.

    CPT code 27580 describes surgical arthrodesis (fusion) of the knee joint using any technique to address conditions such as infection, loss of quadriceps function, failed total knee replacement, or congenital femoral dysgenesis; the service is an operative orthopedic procedure typically performed in an inpatient or outpatient hospital operating room or ambulatory surgical center under appropriate anesthesia.

    For related coverage guidance, see recent payer policy updates: Implants for Joint Pain, Orthopedic Applications of Stem Cell Therapy, Bone Lengthening (Distraction Osteogenesis).

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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old male with a long-standing history of right total knee arthroplasty presents with chronic pain, deep periprosthetic infection confirmed by aspiration culture, and radiographic loosening of the prosthesis. The patient has marked instability and loss of effective quadriceps mechanism. After failed attempts at irrigation and debridement and a staged revision, the orthopedic surgeon schedules a knee arthrodesis to address persistent infection and restore a stable, pain-free limb capable of weightbearing.

    The clinical workflow includes preoperative optimization (infection control, medical clearance, informed consent), intraoperative removal of any remaining hardware and infected tissue, preparation of joint surfaces, and fixation using an intramedullary rod or plate with bone graft as needed to achieve fusion. Perioperative antibiotics are administered based on cultures. Postoperative care includes immobilization, pain control, DVT prophylaxis, wound surveillance, and progressive weightbearing guided by radiographic evidence of fusion. Typical admission is to an inpatient hospital or specialized orthopedic surgical center with expected extended recovery and outpatient follow-up for radiographic checks and rehabilitation.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    20680Removal of implant; deep (e.g., intramedullary rod)Performed before or during knee arthrodesis to remove failed prosthesis or hardware.
    27096Excision of proximal tibial lesion, open; with or without graftMay be used when debridement requires resection of tibial bone during preparation for fusion.
    22830Arthrodesis, posterior or posterolateral technique, single level; thoracic or lumbar — (Note: not directly related to knee)Data not applicable; included only if spinal fusion is performed concurrently — otherwise not used.
    27447Arthroplasty, knee, revision (total knee)Often part of the differential coding context; performed when conversion to another revision is attempted prior to fusion.
    20930Allograft, morselized, or placement of bone graftUsed when structural or morselized bone graft is placed to enhance fusion during arthrodesis.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207W00000X
    2086S0102X
    207LP2900X
    363L00000X
    207X00000X
    251V00000X
    103TR0400X
    224ZE0001X

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 2

    10 rows

    PolicyPayerEffective Date
    Implants for Joint PainBlue Cross Blue Shield - Rhode Island2027-03-01
    Orthopedic Applications of Stem Cell TherapyBlue Cross Blue Shield - Rhode Island2027-01-01
    Bone Lengthening (Distraction Osteogenesis)Blue Cross Blue Shield - North Dakota2027-01-01
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Sacroiliac Joint Fusion for the Treatment of Adult Low-Back Pain Medical PolicyHealth-New-England2026-12-01
    Bone Grafts and Stabilization Devices for Spinal Defects - Medical PolicyHealth-New-England2026-12-01
    Implantable Shock Absorbers for Treatment of Knee Osteoarthritisblue cross blue shield - louisiana2026-12-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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