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    OpenPayerBilling CodesIncision Procedures on the Femur (Thigh Region) and Knee JointCPT cpt-27301-deep-thigh-knee-abscess-drainage
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    CPT 27301: Incision and Drainage, Deep Thigh or Knee Abscess

    Medicare pays $741 on average nationally for this procedure.

    CPT code 27301 describes an incision and drainage procedure of an abscess, bursa, or hematoma located in the deep structures of the thigh or knee region; this surgical service treats deep soft-tissue infection and relieves pain. Service type: incision and drainage, deep soft tissue; typical site of service: operating room, procedure room, or emergency department for deep thigh or knee infections.

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 46-year-old male presents to the emergency department with a 48-hour history of escalating left thigh pain, swelling, erythema, and fever. Physical examination reveals a fluctuant, tender deep-seated mass in the anterior thigh with limited knee flexion. Point-of-care ultrasound suggests a localized fluid collection deep to the fascia. Laboratory tests show leukocytosis and elevated inflammatory markers. The orthopedic surgeon evaluates the patient, documents the indication for drainage of a deep abscess in the thigh, obtains informed consent, and schedules an incision and drainage procedure under procedural sedation in the operating room. The workflow includes preoperative antibiotics as indicated, positioning and surgical prep, a deep incision through skin and subcutaneous tissue into the deep fascial plane, evacuation of purulent material, thorough irrigation, hemostasis, placement of a drain if needed, specimen collection for culture, and postoperative wound care instructions with follow-up for culture results and wound checks. Typical sites of service are the hospital operating room or the emergency department procedure area. Service type: surgical, deep tissue incision and drainage of the thigh/knee region for infection control and pain relief.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    10060Incision and drainage of abscess; simple or singlePerformed for superficial abscesses; may be billed when superficial drainage is done instead of deep drainage.
    10061Incision and drainage of abscess; complicated or multipleUsed for multiple or complicated superficial abscesses; may accompany deeper procedures if multiple sites are treated.
    20005Drainage of hematoma, seroma or fluid collection (eg, hematoma) deep in soft tissues; without drainage tube, complicatedMay be used when draining deep hematoma of thigh/knee region rather than purulent abscess.
    10160Puncture aspiration of abscess, simple or singleUsed when aspiration (needle) rather than incision is performed; may be an initial attempt before surgical I&D.
    11042Debridement, subcutaneous tissue (eg, open wounds, non-healing)May be used when significant necrotic tissue debridement is required in conjunction with drainage.
    10180Incision and drainage, complex/infected pilonidal cyst; or extensive drainageMay be relevant when complex soft-tissue infections requiring wide drainage techniques are performed.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    207L00000X
    208000000X
    208800000X
    213E00000X
    3416S0300X
    207QB0505X
    171R00000X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Related Codes

    CPT-27303-INCISION-OF-BONE-CORTEX-UPPER-LEG-KNEE

    CPT 27303: Cortical Incision/Drill for Upper Leg or Knee Bone Abscess

    CPT-27305-ILIOTIBIAL-BAND-OPEN-TENOTOMY

    CPT 27305: Iliotibial Band Open Tenotomy

    CPT-27306-PERCUTANEOUS-TENOTOMY-ADDUCTOR-HAMSTRING

    CPT 27306: Percutaneous Tenotomy of Adductor or Hamstring Tendon

    CPT-27307-PERCUTANEOUS-TENOTOMY-ADDUCTORS-HAMSTRINGS

    CPT 27307: Percutaneous Tenotomy of Adductor or Hamstring Tendons

    CPT-27310-KNEE-ARTHROTOMY-EXPLORATION-AND-DRAINAGE

    CPT 27310: Incision, drainage, and exploration of knee joint

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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