CPT code 25927 denotes surgical amputation of the fingers and a portion of the hand through the metacarpal bones. This code captures an operative procedure used in cases of severe hand trauma, necrosis, infection, or other conditions necessitating removal of distal hand structures at the metacarpal level. Nationally, accurate coding for major hand amputations is important for clinical registry reporting, quality measurement, and consistent claims adjudication across payers.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find an overview of the clinical context for amputation at the metacarpal level, typical sites of service, and the payer landscape relevant to coverage and billing. The publication summarizes common modifiers and administrative considerations when submitting claims for major hand amputation and outlines where benchmarking and policy updates commonly affect reimbursement and documentation requirements.

This resource provides clinicians, coding professionals, and billing managers with a concise reference to understand what CPT code 25927 represents, how it is used in practice, and the administrative elements that typically accompany claims for this major operative service. Data not available in the input are noted where applicable.