CPT code 21151 denotes LeFort II midface reconstruction using microsurgical techniques and bone grafting to correct congenital or acquired facial deformities such as Treacher Collins syndrome. This complex craniofacial procedure is clinically significant because it restores facial form and function, often requiring multidisciplinary teams and specialized hospital resources. Nationally, proper coding and coverage recognition affect access to reconstructive care and resource planning for tertiary surgical centers.

Key payers discussed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise clinical and billing orientation to the code, typical sites of service, and what to expect in claims processing and payer interactions. The publication outlines common modifiers and payer considerations where available, summarizes relevant clinical context for surgical teams and billing staff, and highlights areas where data are not available in the input.

This summary provides health system leaders, coding professionals, and clinicians with the context needed to classify services correctly, anticipate payer engagement, and understand the role of CPT code 21151 in delivering complex craniofacial care across hospital settings.