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    v1.0.28
    OpenPayerBilling CodesDestruction Procedures on Malignant Lesions of the Integumentary SystemCPT cpt-17280-destruction-of-malignant-lesion-0-5-cm-face-nose-lips
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    CPT 17280: Destruction of Malignant Skin Lesion, ≤0.5 cm

    Medicare pays $143 on average nationally for this procedure.

    CPT code 17280 describes destruction of a malignant lesion on the face, ears, eyelids, nose, lips, or mucous membrane using modalities such as chemosurgery, cryosurgery, electrosurgery, or other techniques for a lesion 0.5 cm or less in diameter; the service type is destruction of malignant skin lesion and the typical site of service is an ambulatory clinic, dermatology office, or outpatient procedure room.

    For related coverage guidance, see recent payer policy updates: Onychomycosis diagnostic testing and coverage, Topical Acne-Non-Retinoid Products, Dermatology - Vtama Drug Quantity Management Policy - Per Days.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old patient presents to a dermatology clinic with a biopsy-confirmed basal cell carcinoma measuring 0.4 cm on the lateral nose. The clinician documents a focused skin exam, reviews the biopsy pathology, discusses treatment options, and proceeds with office-based destruction of the lesion using cryosurgery under local anesthesia. The procedure is performed in the outpatient dermatology clinic; vital signs are monitored, informed consent is obtained, local anesthesia may be administered, and post-procedure wound care instructions are given. Clinic staff document lesion size, exact anatomic location (nose, left side), technique used (cryosurgery), and diagnosis. The typical workflow includes: pre-procedure evaluation and consent, preparation and photography of the lesion, administration of local anesthetic if required, lesion destruction using an appropriate modality, immediate post-procedure assessment, and documentation of follow-up instructions and plan for surveillance or additional treatment if margins or pathology require further care.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11102Tangential biopsy of skin (e.g., shave), single lesionPerformed to obtain tissue diagnosis prior to destruction when pathology is needed
    11100Biopsy of single lesion, punchAlternative diagnostic biopsy method prior to definitive destruction
    17000Destruction of benign lesions, first lesionWhen benign lesions are treated in the same encounter; distinguishes malignant-specific codes
    17286Destruction of malignant lesion, face/neck/ scalp/ankle/foot, lesion diameter 1.1 to 2.0 cmUsed when lesion size exceeds the 0.5 cm threshold for 17280 and requires a different code
    99024Postoperative follow-up visit global surgical packageUsed by some practices to document routine postoperative follow-up depending on payer policies

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207N00000XDermatology PhysicianA dermatologist is trained to diagnose and treat pediatric and adult patients with benign and malignant disorders of the skin, mouth, external genital…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    282N00000XGeneral Acute Care HospitalAn acute general hospital is an institution whose primary function is to provide inpatient diagnostic and therapeutic services for a variety of medica…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    2084S0010XSports Medicine (Psychiatry & Neurology) PhysicianA psychiatrist or neurologist who specializes in the diagnosis and treatment of sports related conditions and injuries.
    320800000XMental Illness Community Based Residential Treatment FacilityA home-like residential facility providing psychiatric treatment and psycho/social rehabilitative services to individuals diagnosed with mental illnes…
    207RX0202XMedical Oncology PhysicianAn internist who specializes in the diagnosis and treatment of all types of cancer and other benign and malignant tumors. This specialist decides on a…
    2080P0214XPediatric Pulmonology PhysicianA pediatrician dedicated to the prevention and treatment of all respiratory diseases affecting infants, children and young adults. This specialist is …

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    10 rows

    PolicyPayerEffective Date
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Topical Acne-Non-Retinoid ProductsCigna2026-08-15
    Dermatology - Vtama Drug Quantity Management Policy - Per DaysCigna2026-08-15
    Medical Necessity Guidelines: Acne and Rosacea Medicationsharvard pilgrim health care2026-08-11
    Pharmacologic Treatment of PsoriasisPremera Bluecross2026-08-01
    Winlevi (clascoterone 1% cream) — Topical AcneCigna2026-08-01
    Spevigo (spesolimab‑sbzo) for generalized pustular psoriasisUnitedHealthcare2026-08-01
    Onychomycosis Testingblue cross blue shield - louisiana2026-08-01
    Spesolimab-sbzo (Spevigoblue cross blue shield - tennessee2026-07-31
    Home ultraviolet light therapy equipment for skin conditionsselect_health2026-07-01

    Related Codes

    CPT-17260-MALIGNANT-LESION-DESTRUCTION-TRUNK-ARMS-LEGS-05CM

    CPT 17260: Destruction of Malignant Lesion on Trunk/Arms/Legs ≤0.5 cm

    CPT-17261-DESTRUCTION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-06-10-CM

    CPT 17261: Destruction of Malignant Lesion, Trunk/Arms/Legs 0.6–1.0 cm

    CPT-17262-DESTRUCTION-MALIGNANT-LESION-1-1-TO-2-0-CM-TRUNK-ARMS-LEGS

    CPT 17262: Destruction of Malignant Lesion, Trunk/Arms/Legs 1.1–2.0 cm

    CPT-17263-DESTRUCTION-MALIGNANT-LESION-2-1-3-0-CM-TRUNK-ARMS-LEGS

    CPT 17263: Destruction of Malignant Lesion on Trunk/Arms/Legs (2.1–3.0 cm)

    CPT-17264-DESTRUCTION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-3CM-4CM

    CPT 17264: Destruction of Malignant Lesion on Trunk/Arms/Legs 3.1–4.0 cm

    CPT-17266-DESTRUCTION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-GT4CM

    CPT 17266: Destruction of Malignant Lesion on Trunk/Arms/Legs (>4.0 cm)

    CPT-17270-DESTRUCTION-MALIGNANT-LESION-05-CM-OR-LESS

    CPT 17270: Destruction of Malignant Skin Lesion ≤0.5 cm

    CPT-17271-DESTRUCTION-MALIGNANT-SKIN-LESION-0-6-1-0-CM

    CPT 17271: Destruction of Malignant Lesion 0.6–1.0 cm

    CPT-17272-DESTRUCTION-MALIGNANT-LESION-1-1-TO-2-0-CM

    CPT 17272: Destruction of Malignant Lesion 1.1–2.0 cm

    CPT-17273-DESTRUCTION-MALIGNANT-LESION-2-1-TO-3-0-CM-SCALP-NECK-HANDS-FEET-GENITALIA

    CPT 17273: Destruction of Malignant Skin Lesion 2.1–3.0 cm

    Showing 1–10 of 17

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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