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    OpenPayerBilling CodesDestruction Procedures on Malignant Lesions of the Integumentary SystemCPT cpt-17264-destruction-malignant-lesion-trunk-arms-legs-3cm-4cm
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    CPT 17264: Destruction of Malignant Lesion on Trunk/Arms/Legs 3.1–4.0 cm

    Medicare pays $209 on average nationally for this procedure.

    CPT code 17264 describes destruction of a malignant lesion on the trunk, arms, or legs using methods such as chemosurgery, cryosurgery, electrosurgery, or similar techniques for a lesion measuring 3.1 cm to 4.0 cm in diameter; the service is a dermatologic lesion destruction procedure and the typical site of service is an outpatient dermatology clinic, ambulatory surgical center, or physician office where minor surgical procedures are performed.

    For related coverage guidance, see recent payer policy updates: Mohs Micrographic Surgery, Mohs Micrographic Surgery, Mohs Micrographic Surgery.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old male presents to the dermatology clinic with a biopsy-confirmed cutaneous squamous cell carcinoma on the lateral right thigh measuring 3.5 cm in greatest diameter. The lesion is malignant and located on the trunk/upper or lower extremity. The clinical workflow includes pre-procedure evaluation (history, focused skin exam, and review of anticoagulation status), informed consent, lesion measurement and marking, local anesthesia administration, and lesion destruction using cryosurgery or electrosurgery in an outpatient clinic or ambulatory surgery center. Post-procedure wound care instructions are provided and a short follow-up visit is scheduled to assess healing and monitor for recurrence. Typical site of service is an outpatient dermatology clinic or ambulatory surgery center. Service type: lesion destruction (non-excisional) of a malignant lesion measuring 3.1–4.0 cm on trunk, arms, or legs, consistent with 17264.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11102Tangential biopsy of skin (e.g., shave, scoop), single lesionDiagnostic biopsy performed prior to definitive destruction to establish malignancy.
    11606Excision, malignant lesion including margins, trunk, arms or legs; diameter 1.1 to 2.0 cmAlternative definitive treatment when excision is chosen instead of destructive modalities for malignant lesions.
    17000Destruction (e.g., laser surgery, electrosurgery, cryosurgery, chemosurgery, surgical curettement), premalignant lesions (e.g., actinic keratoses), first lesionRelated destruction code for premalignant lesions; different diagnosis and code series.
    12032Repair, intermediate, wounds of trunk, arms or legs; 2.6 cm to 7.5 cmMay be performed if excision and primary closure are required instead of or following destructive procedures.
    99070Supplies and materials (except spectacles), used for medical purposes, unlisted devicesUsed to report special supplies or devices consumed during the procedure when not otherwise included.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Q00000X
    2080P0207X
    208D00000X
    363L00000X
    2083B0002X
    1223D0001X
    156FX1201X
    2472V0600X

    Related ICD-10-CM Codes

    20 rows

    ICD-10-CM CodeDescription
    C43.9Malignant melanoma of skin, unspecified
    C44.311Basal cell carcinoma of skin of nose
    C44.319Basal cell carcinoma of skin of other parts of face
    C44.511Basal cell carcinoma of skin of breast
    C44.519Basal cell carcinoma of skin of other part of trunk
    C44.611Basal cell carcinoma of skin of unspecified upper limb, including shoulder
    C44.612Basal cell carcinoma of skin of right upper limb, including shoulder
    C44.619Basal cell carcinoma of skin of left upper limb, including shoulder
    D03.0Melanoma in situ of lip
    D03.9Melanoma in situ, unspecified

    Showing 1–10 of 20

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    10 rows

    PolicyPayerEffective Date
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    FilsuvezCigna2026-11-01
    Destruction of Pre-Malignant Skin LesionsAnthem2026-10-01
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Treatment of Capillary Malformations (Port Wine Stains)universityofutahhealthplans2026-09-28
    AnzupgoCigna2026-09-15
    Hyperhidrosispriority_health_medicare2026-09-01
    Zevaskyn Coverage for Recessive Dystrophic Epidermolysis BullosaCigna2026-09-01

    Related Codes

    CPT-17260-MALIGNANT-LESION-DESTRUCTION-TRUNK-ARMS-LEGS-05CM

    CPT 17260: Destruction of Malignant Lesion on Trunk/Arms/Legs ≤0.5 cm

    CPT-17261-DESTRUCTION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-06-10-CM

    CPT 17261: Destruction of Malignant Lesion, Trunk/Arms/Legs 0.6–1.0 cm

    CPT-17262-DESTRUCTION-MALIGNANT-LESION-1-1-TO-2-0-CM-TRUNK-ARMS-LEGS

    CPT 17262: Destruction of Malignant Lesion, Trunk/Arms/Legs 1.1–2.0 cm

    CPT-17263-DESTRUCTION-MALIGNANT-LESION-2-1-3-0-CM-TRUNK-ARMS-LEGS

    CPT 17263: Destruction of Malignant Lesion on Trunk/Arms/Legs (2.1–3.0 cm)

    CPT-17266-DESTRUCTION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-GT4CM

    CPT 17266: Destruction of Malignant Lesion on Trunk/Arms/Legs (>4.0 cm)

    CPT-17270-DESTRUCTION-MALIGNANT-LESION-05-CM-OR-LESS

    CPT 17270: Destruction of Malignant Skin Lesion ≤0.5 cm

    CPT-17271-DESTRUCTION-MALIGNANT-SKIN-LESION-0-6-1-0-CM

    CPT 17271: Destruction of Malignant Lesion 0.6–1.0 cm

    CPT-17272-DESTRUCTION-MALIGNANT-LESION-1-1-TO-2-0-CM

    CPT 17272: Destruction of Malignant Lesion 1.1–2.0 cm

    CPT-17273-DESTRUCTION-MALIGNANT-LESION-2-1-TO-3-0-CM-SCALP-NECK-HANDS-FEET-GENITALIA

    CPT 17273: Destruction of Malignant Skin Lesion 2.1–3.0 cm

    CPT-17274-DESTRUCTION-MALIGNANT-SKIN-LESION-3-1-4-0-CM

    CPT 17274: Destruction of Malignant Skin Lesion 3.1–4.0 cm

    Showing 1–10 of 17

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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