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    v1.0.28
    OpenPayerBilling CodesExcision-Malignant Lesions Procedures on the SkinCPT cpt-11643-excision-malignant-skin-lesion-face-2-1-3-0-cm
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    CPT 11643: Excision of Malignant Skin Lesion, Face 2.1–3.0 cm

    Medicare pays $326 on average nationally for this procedure.

    CPT code 11643 describes surgical excision of a malignant skin lesion on the face, ears, eyelids, nose, or lips with margins for a lesion 2.1 to 3.0 cm in diameter; the service is excision of a malignant lesion and the typical site of service is an operating room, procedure room, or outpatient surgical clinic for dermatologic or surgical oncology procedures.

    For related coverage guidance, see recent payer policy updates: Onychomycosis diagnostic testing and coverage, Topical Acne-Non-Retinoid Products, Dermatology - Vtama Drug Quantity Management Policy - Per Days.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old male presents to the dermatologic surgery clinic with a biopsy-proven invasive cutaneous squamous cell carcinoma located on the left cheek measuring approximately 2.4 cm in greatest diameter. The patient has controlled hypertension and no anticoagulation. After pre-operative assessment, the surgeon discusses surgical options and obtains informed consent for excision with appropriate margins and anticipated local flap reconstruction. On the day of service the procedure is performed in an outpatient ambulatory surgery center under local anesthesia with monitored anesthesia care; the surgeon excises the malignant lesion including margins, specimens are labeled and sent for pathology, hemostasis achieved, and the defect is repaired with a local advancement flap. The clinical workflow includes pre-op history and physical, lesion mapping and measurements documented, photographic documentation, lesion excision with margin documentation (size 2.4 cm lesion), specimen handling and pathology requisition, surgical repair, post-op instructions, and coding/billing using the appropriate CPT code for excision on the face.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11642Excision, malignant lesion including margins, diameter 1.1 to 2.0 cm, face, ears, eyelids, nose, lipsUsed when lesion size falls in the 1.1–2.0 cm range; codes should reflect actual measured lesion diameter.
    11644Excision, malignant lesion including margins, diameter 3.1 to 4.0 cm, face, ears, eyelids, nose, lipsUsed when lesion diameter exceeds 3.0 cm and falls into the next size bracket; select the code matching the final excised lesion size.
    14060Adjacent tissue transfer or rearrangement, forehead, cheeks, chin, mouth, neck; defect 10.1 cm to 30.0 cmRepresents common reconstructive techniques (local flaps) used after wide excision on the face when primary closure is not possible.
    12051Repair, intermediate, face, ears, eyelids, nose, lips; 2.6 cm to 7.5 cmUsed for layered (intermediate) closure when direct repair is performed after excision and when repair complexity and size meet code descriptors.
    88305Level IV pathology; surgical pathology, gross and microscopic examinationUsed for histopathologic examination of the excised specimen to confirm margins and diagnosis; billed by pathology services.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    2086S0122XPlastic and Reconstructive Surgery PhysicianA surgeon who specializes in plastic and reconstructive surgery.
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    207YX0901XOtology & Neurotology PhysicianAn otolaryngologist who treats diseases of the ear and temporal bone, including disorders of hearing and balance. The additional training in otology a…
    126800000XDental AssistantAn individual who may or may not have completed an accredited dental assisting education program and who aids the dentist in providing patient care se…
    2080S0010XPediatric Sports Medicine PhysicianA pediatrician who is responsible for continuous care in the field of sports medicine, not only for the enhancement of health and fitness, but also fo…

    Related ICD-10-CM Codes

    19 rows

    ICD-10-CM CodeDescription
    C43.0Malignant melanoma of lip
    C43.4Malignant melanoma of scalp and neck
    C43.9Malignant melanoma of skin, unspecified
    C44.311Basal cell carcinoma of skin of nose
    C44.319Basal cell carcinoma of skin of other parts of face
    C44.511Basal cell carcinoma of skin of breast
    C44.519Basal cell carcinoma of skin of other part of trunk
    C44.611Basal cell carcinoma of skin of unspecified upper limb, including shoulder
    C44.619Basal cell carcinoma of skin of left upper limb, including shoulder
    C44.711Basal cell carcinoma of skin of unspecified lower limb, including hip

    Showing 1–10 of 19

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    5 rows

    PolicyPayerEffective Date
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Topical Acne-Non-Retinoid ProductsCigna2026-08-15
    Dermatology - Vtama Drug Quantity Management Policy - Per DaysCigna2026-08-15
    Medical Necessity Guidelines: Acne and Rosacea Medicationsharvard pilgrim health care2026-08-11
    Winlevi (clascoterone 1% cream) — Topical AcneCigna2026-08-01

    Related Codes

    CPT-11600-EXCISION-MALIGNANT-LESION-05-CM-TRUNK-ARMS-LEGS

    CPT 11600: Excision of Malignant Lesion, ≤0.5 cm, Trunk/Arms/Legs

    CPT-11601-EXCISION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-0-6-1-0-CM

    CPT 11601: Excision of Malignant Skin Lesion, Trunk/Arms/Legs, 0.6–1.0 cm

    CPT-11602-EXCISION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-1-1-2-0CM

    CPT 11602: Excision of Malignant Lesion, Trunk/Arms/Legs 1.1–2.0 cm

    CPT-11603-EXCISION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-2-1-3-0-CM

    CPT 11603: Excision of Malignant Lesion, Trunk/Arms/Legs 2.1–3.0 cm

    CPT-11604-EXCISION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-3-1-4-0-CM

    CPT 11604: Excision of Malignant Lesion, Trunk/Arms/Legs 3.1–4.0 cm

    CPT-11606-EXCISION-MALIGNANT-LESION-TRUNK-ARMS-LEGS-OVER-4CM

    CPT 11606: Excision of Malignant Skin Lesion >4.0 cm on Trunk/Arms/Legs

    CPT-11620-EXCISION-MALIGNANT-SKIN-LESION-SMALL-DIAMETER-SCALP-NECK-HANDS-FEET-GENITALIA

    CPT 11620: Excision of Malignant Skin Lesion, ≤0.5 cm

    CPT-11621-EXCISION-MALIGNANT-LESION-06-10-MM-SCALP-NECK-HANDS-FEET-GENITALIA

    CPT 11621: Excision of Malignant Skin Lesion, 0.6–1.0 cm

    CPT-11622-EXCISION-MALIGNANT-LESION-1-1-TO-2CM-SCALP-NECK-HANDS-FEET-GENITALIA

    CPT 11622: Excision of Malignant Skin Lesion 1.1–2.0 cm

    CPT-11623-EXCISION-MALIGNANT-SKIN-LESION-2-1-3CM-SCALP-NECK-HANDS-FEET-GENITALIA

    CPT 11623: Excision of Malignant Lesion, 2.1–3.0 cm, Scalp/Neck/Hands/Feet/Genitalia

    Showing 1–10 of 17

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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