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    v1.0.28
    OpenPayerBilling CodesPatient HistoryCPT cpt-1125f-cancer-pain-severity-assessment-during-therapy
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    CPT 1125F: Cancer Pain Severity Measurement During Chemotherapy or Radiotherapy

    CPT code 1125F documents that the provider measured the severity of pain in a patient with cancer who received chemotherapy or radiotherapy during the measurement period; service type is symptom assessment / pain severity measurement and typical site of service is oncology clinic or infusion/radiation treatment setting.

    For related coverage guidance, see recent payer policy updates: Prolonged Services for Labor Management, Prolonged Services for Labor Management, Cervical Cancer Screening.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old patient with metastatic breast cancer is receiving outpatient chemotherapy in an oncology infusion center. During a routine treatment visit, the oncology nurse or treating clinician performs a standardized pain assessment documenting presence and severity of cancer-related pain while the patient receives chemotherapy or radiotherapy. The assessment occurs during the measurement period (during an active course of chemo- or radiotherapy) and is recorded in the medical record. The documented finding that the patient experiences pain is reported with 1125F. Typical workflow steps include intake assessment, pain severity measurement (numeric rating scale or validated tool), documentation in the electronic medical record, clinician review, and inclusion of the code on the encounter or quality reporting documentation. Typical site of service is an outpatient oncology clinic or infusion center. Service type is a patient-reported/clinician-assessed symptom severity measurement specific to cancer treatment visits.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99211Office or other outpatient visit for the evaluation and management of an established patient that may not require the presence of a physicianOften billed for brief nursing or clinician visits during infusion where pain assessment is performed along with other routine care
    99213Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutesCommon E/M code used when a clinician provides a focused assessment and documents pain severity during a treatment visit
    G0490Electronic clinical quality measure (eCQM) reportingUsed by practices reporting quality measures related to symptom assessments during cancer treatment (payer-specific reporting)
    96127Brief emotional/behavioral assessment (e.g., depression screening)Sometimes performed alongside pain assessment to evaluate psychosocial contributors to pain during cancer therapy
    96365Intravenous infusion, therapeutic, prophylactic, or diagnostic; initial, up to 1 hourFrequently submitted for chemotherapy administration visits during which the pain severity measurement occurs

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    8PModifier 8P—Performance Measure Reporting Modifier – Action Not Performed, Reason Not Otherwise Specified— is appended only to CPT Category II quality-reporting codes to indicate that the specified…- Use modifier -8P only with CPT Category II codes when the quality-measure action was not performed for an eligible patient and there is no documented reason in the medical record for omitting the…
    95Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    27Modifier 27 indicates a separate, subsequent outpatient hospital E/M service provided to the same patient on the same date by a different provider in a hospital outpatient setting. It is a…- Use modifier -27 on facility (hospital outpatient/ambulatory service center) claims to report a subsequent, separate, and distinct outpatient E/M service provided to the same patient on the same…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207RG0100XGastroenterology PhysicianAn internist who specializes in diagnosis and treatment of diseases of the digestive organs including the stomach, bowels, liver and gallbladder. This…
    207RH0000XHematology (Internal Medicine) PhysicianAn internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, cl…
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    315P00000XIntellectual Disabilities Intermediate Care FacilityAn intermediate care facility providing services for individuals with intellectual disabilities.
    207KA0200XAllergy PhysicianA physician who specializes in the diagnosis, treatment, and management of allergies.
    111NT0100XThermography ChiropractorThe NUCC recommends this code not be used. Choose a more appropriate code.

    Related Payer Policy Updates

    Specialty: Obstetrics/Gynecology1 / 3

    8 rows

    PolicyPayerEffective Date
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Cervical Cancer ScreeningOscar Health2026-10-01
    Prenatal Testing for Fetal AneuploidyOscar Health2026-10-01
    Diagnosis of VaginitisOscar Health2026-10-01
    Prenatal Screening (Nongenetic)Oscar Health2026-10-01
    View PDF of Maternal Serum Biomarkers for Prediction of Adverse Obstetric Outcomes, Effective 10/1/2026 in MedicalBlue Cross Blue Shield - Rhode Island2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesBluecross Idaho2026-09-01

    Related Codes

    CPT-1000F-CATEGORY-II-PERFORMANCE-MEASURE

    CPT 1000F: Tobacco Use Status Assessment

    CPT-1002F-NO-SUMMARY-AVAILABLE

    CPT 1002F: No Summary available

    CPT-1003F-PERFORMANCE-MEASURE

    CPT 1003F: Preventive Care Tobacco Use Counseling

    CPT-1004F-NO-SUMMARY-AVAILABLE

    CPT 1004F: Health Status Assessment

    CPT-1005F-NO-SUMMARY-AVAILABLE

    CPT 1005F: Peripheral Oxygen Saturation Assessment

    CPT-1006F-BRIEF-SUMMARY-NOT-AVAILABLE

    CPT 1006F: No Summary Available

    CPT-1007F-NO-SUMMARY-AVAILABLE

    CPT 1007F: Influenza Vaccination Administered

    CPT-1008F-UNSPECIFIED-SERVICE

    CPT 1008F: Depression Screening, Brief Standardized Assessment

    CPT-1010F-ANGINA-SEVERITY-ASSESSMENT-CAD-ACTIVITY-RESPONSE

    CPT 1010F: Angina Activity Assessment in Coronary Artery Disease

    CPT-1011F-THERAPEUTIC-MANAGEMENT-CORONARY-ARTERY-DISEASE-ANGINA

    CPT 1011F: Therapeutic Management for CAD with Angina

    Showing 1–10 of 81

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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