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    v1.0.30
    OpenPayerBilling CodesMalignant Renal Tissue Histotripsy ProcedureCPT cpt-0888t-focused-ultrasound-ablation-renal-tumor
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    CPT 0888T: Ultrasound-Guided Renal Tumor Ablation

    CPT code 0888T describes ultrasound-directed thermal ablation of cancerous renal (kidney) tissue using a specialized device with image guidance; this is a percutaneous or minimally invasive image-guided tumor ablation procedure typically performed in an outpatient interventional radiology or ambulatory surgical center setting and billed as an image-guided therapeutic procedure for renal tumor destruction.

    For related coverage guidance, see recent payer policy updates: Lutetium Therapeutic Radiopharmaceuticals - Medical Policy, Radiation oncology coverage and treatment delivery guidelines, Transarterial Radioembolization (TARE)/Selective Internal Radiation Therapy (SIRT) for the Treatment of Malignant Cancers of the Liver.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 65-year-old with a solitary, biopsy-proven renal cell carcinoma (RCC) in a single kidney or a small renal mass in a patient at increased surgical risk due to comorbidities (cardiopulmonary disease, anticoagulation, or prior abdominal surgery). The patient presents with imaging surveillance demonstrating a 2–4 cm enhancing renal cortical mass suspicious for malignancy. Pre-procedure workup includes cross-sectional imaging (CT or MRI) to localize the lesion, laboratory testing (coagulation panel, basic metabolic panel), and a pre-anesthesia evaluation.

    The clinical workflow: the interventional radiologist or urologist performs pre-procedure planning with image review and discusses risks/benefits with the patient. On the day of service the patient is brought to an outpatient procedure suite or hospital operating room depending on anesthesia needs. Under conscious sedation or general anesthesia, percutaneous (or laparoscopic) placement of a specialized ultrasound energy delivery device into the renal tumor is performed using real-time image guidance (ultrasound and/or CT). The device delivers focused ultrasound energy to ablate tumor tissue while the operator monitors ablation extent and surrounding structures. Post-procedure, the patient is observed in recovery, has post-procedure imaging or immediate ultrasound/CT to evaluate for complications, and receives discharge instructions or inpatient admission if clinically indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    76942Ultrasonic guidance for needle placement (e.g., biopsy, aspiration, injection, localization device), imaging supervision and interpretationUsed for real-time ultrasound guidance during percutaneous device placement into the renal lesion.
    77012CT guidance for needle placement (eg, biopsy, aspiration, injection, localization device), imaging supervision and interpretationUsed when CT guidance is utilized for device placement or to monitor ablation.
    76930Magnetic resonance guidance for needle placement, imaging supervision and interpretationUsed if MR guidance is employed for targeting or monitoring the ablation.
    51728Placement of ureteral stent, with or without cystoscopy (if needed)May be performed pre- or post-ablation if urinary drainage or decompression is required.
    90901Application of focused ultrasound therapy (example—procedure code placeholder for related thermal ablation services)Represents related thermal ablation services and context for billing and crosswalks; used in workflow when other ablation codes are applicable.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2080P0201X
    363L00000X
    136A00000X
    251F00000X
    2278P1004X
    363LW0102X
    106H00000X
    246QH0000X

    Related Payer Policy Updates

    Specialty: Radiation Oncology1 / 3

    10 rows

    PolicyPayerEffective Date
    Lutetium Therapeutic Radiopharmaceuticals - Medical PolicyHealth-New-England2027-02-01
    Radiation oncology coverage and treatment delivery guidelinesevicore2026-11-05
    Transarterial Radioembolization (TARE)/Selective Internal Radiation Therapy (SIRT) for the Treatment of Malignant Cancers of the LiverColorado Rocky Mountain Health Plans2026-11-01
    Proton Beam Therapyuniversityofutahhealthplans2026-10-25
    Radioembolization for Primary and Metastatic Liver Tumorspremerabluecrossofwashington2026-10-01
    Radioembolization for Primary and Metastatic Liver Tumorspremerabluecrossofwashington2026-10-01
    Radioembolization for Liver Malignanciespremerabluecrossofwashington2026-10-01
    Radiation and Oncologic ProceduresUnitedHealthcare2026-09-01
    Superficial Radiation Therapy for the Treatment of Nonmelanoma Skin Cancers - Medical PolicyHealth-New-England2026-08-01
    Electronic Brachytherapy for Nonmelanoma Skin CancerBluecross Idaho2026-07-30

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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