CPT 0760T: Slide Digitization for Initial Immunohistochemistry

CPT code 0760T describes clinical staff work to scan and digitize images from glass microscope slides for immediate or later pathologic diagnosis, specifically for slides prepared for an initial single-antibody immunohistochemistry stain (88342). This add-on service is typically performed by pathology laboratory staff as a diagnostic digitization procedure and is most commonly rendered in hospital pathology labs, independent or hospital-based clinical laboratories, and specialized anatomic pathology service locations where digital slide scanning is used to support surgical pathology and immunohistochemistry workflows.

Customize your policy alerts

Sign up for cpt 0760T policy alerts

Get alerted when payer policies referencing 0760T are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Explore openpayer tools

View all tools

CPT 0760T: Slide Digitization for Initial Immunohistochemistry

Customize your policy alerts

Sign up for cpt 0760T policy alerts

Get alerted when payer policies referencing 0760T are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Clinical & Coding Specifications

Clinical Context

A 62-year-old patient undergoes a biopsy for a suspicious breast mass. The pathology laboratory prepares formalin-fixed, paraffin-embedded tissue sections on glass slides and performs an initial single-antibody immunohistochemistry (IHC) stain (for example, estrogen receptor). Clinical staff then operate a whole-slide scanner to digitize the stained glass slides for immediate review by the pathologist and for storage in the laboratory’s digital pathology system. The workflow includes accessioning the specimen, slide labeling and QC, scanning and image QC, and delivery of the digital image to the pathologist for interpretation and integration with morphologic and IHC findings. The service represented by 0760T is billed in addition to the primary pathology IHC staining code (88342) and reflects the clinical staff time and technical activity required to produce diagnostic whole-slide images that support an initial single-antibody IHC exam.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`88342`	Immunohistochemistry or immunocytochemistry, per single antibody stain procedure	Primary pathology procedure described as the initial single-antibody IHC exam; `0760T` is an add-on for digitization of slides prepared for this service.
`88305`	Level IV surgical pathology, gross and microscopic examination	Often performed alongside IHC when surgical specimens require morphologic diagnosis prior to or concurrent with IHC digitization.
`88112`	Cytopathology, single cell or smear preparation, immunocytochemistry	When cytology slides require IHC staining and subsequent digitization similar to tissue IHC workflows.
`88331`	Immunohistochemistry (special stains) interpretation by pathologist, per specimen	Represents pathologist interpretation component that follows scanning; digitized images support the interpretation.
`76930`	Ultrasound guidance for needle biopsy, imaging supervision and interpretation	Procedural code that may precede tissue acquisition; the resulting tissue can undergo IHC staining and digitization billed with `0760T`.

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
80	CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…	- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207K00000X	Allergy & Immunology Physician	An allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
363L00000X	Nurse Practitioner	(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
2084N0400X	Neurology Physician	A Neurologist specializes in the diagnosis and treatment of diseases or impaired function of the brain, spinal cord, peripheral nerves, muscles, auton…
207RG0100X	Gastroenterology Physician	An internist who specializes in diagnosis and treatment of diseases of the digestive organs including the stomach, bowels, liver and gallbladder. This…
163WN0002X	Neonatal Intensive Care Registered Nurse	Nursing Service Providers · Registered Nurse
2279P3900X	Neonatal/Pediatric Registered Respiratory Therapist	The care and treatment of premature infants, newborns and children. This includes management of mechanical ventilation, assessment, diagnostics and g…
207QA0000X	Adolescent Medicine (Family Medicine) Physician	A family medicine physician with multidisciplinary training in the unique physical, psychological and social characteristics of adolescents and their …
208100000X	Physical Medicine & Rehabilitation Physician	Physical medicine and rehabilitation, also referred to as rehabilitation medicine, is the medical specialty concerned with diagnosing, evaluating, and…

CPT 0751T: Slide Digitization for Level II Surgical Pathology

CPT-0752T-SLIDE-DIGITIZATION-SURGICAL-PATHOLOGY-LEVEL-III

CPT 0752T: Slide Digitization for Level III Surgical Pathology

CPT-0753T-SLIDE-DIGITIZATION-LEVEL-IV-SURGICAL-PATHOLOGY

CPT 0753T: Digital Slide Scanning for Level IV Surgical Pathology

CPT-0754T-DIGITAL-SLIDE-DIGITIZATION-LEVEL-V-SURGICAL-PATHOLOGY

CPT 0754T: Slide Digitization for Level V Surgical Pathology

CPT-0755T-SLIDE-DIGITIZATION-LEVEL-VI-SURGICAL-PATHOLOGY

CPT 0755T: Digital Slide Scanning for Surgical Pathology Level VI

CPT-0757T-SLIDE-DIGITIZATION-SPECIAL-STAIN-88313

CPT 0757T: Digital Slide Digitization for Group II Special Stain

CPT-0758T-FROZEN-STAIN-SLIDE-DIGITIZATION

CPT 0758T: Digitization of Slides for Frozen Tissue Histochemical Stain

CPT-0759T-DIGITAL-PATHOLOGY-SLIDE-SCANNING-GROUP-III-STAIN

CPT 0759T: Digitization of Group III Special Stain Slides

CPT-0761T-DIGITAL-SLIDE-SCANNING-IMMUNOHISTOCHEMISTRY

CPT 0761T: Digitization of Slide for Single-Antibody IHC

CPT-0762T-SLIDE-DIGITIZATION-MULTIPLEX-IMMUNOHISTOCHEMISTRY

CPT 0762T: Slide Digitization for Multiplex Immunohistochemistry

Showing 1–10 of 23

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Explore openpayer tools

View all tools

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`88342`	Immunohistochemistry or immunocytochemistry, per single antibody stain procedure	Primary pathology procedure described as the initial single-antibody IHC exam; `0760T` is an add-on for digitization of slides prepared for this service.
`88305`	Level IV surgical pathology, gross and microscopic examination	Often performed alongside IHC when surgical specimens require morphologic diagnosis prior to or concurrent with IHC digitization.
`88112`	Cytopathology, single cell or smear preparation, immunocytochemistry	When cytology slides require IHC staining and subsequent digitization similar to tissue IHC workflows.
`88331`	Immunohistochemistry (special stains) interpretation by pathologist, per specimen	Represents pathologist interpretation component that follows scanning; digitized images support the interpretation.
`76930`	Ultrasound guidance for needle biopsy, imaging supervision and interpretation	Procedural code that may precede tissue acquisition; the resulting tissue can undergo IHC staining and digitization billed with `0760T`.

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
80	CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…	- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207K00000X	Allergy & Immunology Physician	An allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
363L00000X	Nurse Practitioner	(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
2084N0400X	Neurology Physician	A Neurologist specializes in the diagnosis and treatment of diseases or impaired function of the brain, spinal cord, peripheral nerves, muscles, auton…
207RG0100X	Gastroenterology Physician	An internist who specializes in diagnosis and treatment of diseases of the digestive organs including the stomach, bowels, liver and gallbladder. This…
163WN0002X	Neonatal Intensive Care Registered Nurse	Nursing Service Providers · Registered Nurse
2279P3900X	Neonatal/Pediatric Registered Respiratory Therapist	The care and treatment of premature infants, newborns and children. This includes management of mechanical ventilation, assessment, diagnostics and g…
207QA0000X	Adolescent Medicine (Family Medicine) Physician	A family medicine physician with multidisciplinary training in the unique physical, psychological and social characteristics of adolescents and their …
208100000X	Physical Medicine & Rehabilitation Physician	Physical medicine and rehabilitation, also referred to as rehabilitation medicine, is the medical specialty concerned with diagnosing, evaluating, and…

CPT 0751T: Slide Digitization for Level II Surgical Pathology

CPT-0752T-SLIDE-DIGITIZATION-SURGICAL-PATHOLOGY-LEVEL-III

CPT 0752T: Slide Digitization for Level III Surgical Pathology

CPT-0753T-SLIDE-DIGITIZATION-LEVEL-IV-SURGICAL-PATHOLOGY

CPT 0753T: Digital Slide Scanning for Level IV Surgical Pathology

CPT-0754T-DIGITAL-SLIDE-DIGITIZATION-LEVEL-V-SURGICAL-PATHOLOGY

CPT 0754T: Slide Digitization for Level V Surgical Pathology

CPT-0755T-SLIDE-DIGITIZATION-LEVEL-VI-SURGICAL-PATHOLOGY

CPT 0755T: Digital Slide Scanning for Surgical Pathology Level VI

CPT-0757T-SLIDE-DIGITIZATION-SPECIAL-STAIN-88313

CPT 0757T: Digital Slide Digitization for Group II Special Stain

CPT-0758T-FROZEN-STAIN-SLIDE-DIGITIZATION

CPT 0758T: Digitization of Slides for Frozen Tissue Histochemical Stain

CPT-0759T-DIGITAL-PATHOLOGY-SLIDE-SCANNING-GROUP-III-STAIN

CPT 0759T: Digitization of Group III Special Stain Slides

CPT-0761T-DIGITAL-SLIDE-SCANNING-IMMUNOHISTOCHEMISTRY

CPT 0761T: Digitization of Slide for Single-Antibody IHC

CPT-0762T-SLIDE-DIGITIZATION-MULTIPLEX-IMMUNOHISTOCHEMISTRY

CPT 0762T: Slide Digitization for Multiplex Immunohistochemistry

Showing 1–10 of 23

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

CPT 0760T: Slide Digitization for Initial Immunohistochemistry

Sign up for cpt 0760T policy alerts

OpenPayer

CPT 0760T: Slide Digitization for Initial Immunohistochemistry

Sign up for cpt 0760T policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

References

CPT 0760T: Slide Digitization for Initial Immunohistochemistry

Sign up for cpt 0760T policy alerts

CPT 0760T: Slide Digitization for Initial Immunohistochemistry

Sign up for cpt 0760T policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does CPT 0760T represent?

Is 0760T billed separately or with other pathology codes?

Which CPT codes are related to or commonly billed with 0760T?

In what clinical settings and scenarios is 0760T typically performed?

What diagnoses are commonly associated with services billed using 0760T?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does CPT 0760T represent?

Is 0760T billed separately or with other pathology codes?

Which CPT codes are related to or commonly billed with 0760T?

In what clinical settings and scenarios is 0760T typically performed?

What diagnoses are commonly associated with services billed using 0760T?

References