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    v1.0.28
    OpenPayerBilling CodesXenograft Implantation ProcedureCPT cpt-0737t-nonhuman-tissue-graft-joint-implantation
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    CPT 0737T: Nonhuman Tissue Graft Implantation onto Joint Surface

    CPT code 0737T describes implantation of a nonhuman (xenograft) tissue graft onto the surface of a joint; the service is a surgical graft implantation procedure typically performed in an operating room or ambulatory surgery center for joint surface restoration or resurfacing.

    For related coverage guidance, see recent payer policy updates: Reduction Mammoplasty (Breast Reduction Surgery) for Symptomatic Macromastia, Gynecomastia Surgery, Panniculectomy (Abdominal skin/fat surgery).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient with advanced focal articular cartilage damage of the knee presents with persistent joint pain, mechanical symptoms, and failure of conservative therapy (physical therapy, activity modification, and intra-articular injections). The orthopedic surgeon evaluates imaging (MRI showing focal chondral defect) and discusses options including implantation of a nonhuman (xenograft) tissue graft to the articular surface to repair the cartilage defect. On the day of service the patient undergoes preoperative check-in, regional or general anesthesia, sterile preparation of the knee, arthrotomy or arthroscopy for exposure, debridement of unstable cartilage and preparation of a stable defect bed, sizing of the graft, implantation and fixation of the nonhuman tissue graft to the articular surface, verification of graft stability and joint motion, and wound closure. Postoperative workflow includes anesthesia recovery, immediate postoperative neurovascular checks, discharge instructions with weight-bearing precautions and rehabilitation plan, and scheduled outpatient physical therapy and follow-up visits for wound check and graft surveillance.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    29881Arthroscopy, knee, surgical; with meniscectomy (medial OR lateral including any meniscal shaving)May be performed prior to graft implantation to address concomitant meniscal pathology and to debride/prepare the joint.
    27370Open treatment of chondral defect; with implantation of osteochondral autograft(s) (includes harvesting)Alternative cartilage repair technique; may be performed in similar clinical scenarios when autograft is chosen instead of xenograft.
    27096Repair, cartilage defect, knee, open, with osteochondral allograft (including graft procurement)Related cartilage restoration code when allograft tissue is used rather than nonhuman grafts.
    20610Arthrocentesis, aspiration and/or injection; major joint or bursa (e.g., shoulder, hip, knee)Used diagnostically or therapeutically pre- or postoperatively for effusion management or injections.
    29870Arthroscopy, knee, diagnostic, with or without synovial biopsyDiagnostic arthroscopy performed to evaluate cartilage defect and guide decision for implantation.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    207T00000XNeurological Surgery PhysicianA neurological surgeon provides the operative and non-operative management (i.e., prevention, diagnosis, evaluation, treatment, critical care, and reh…
    281P00000XChronic Disease Hospital(1) A hospital including a physical plant and personnel that provides multidisciplinary diagnosis and treatment for diseases that have one or more of …
    152W00000XOptometristDoctors of optometry (ODs) are the primary health care professionals for the eye. Optometrists examine, diagnose, treat, and manage diseases, injurie…

    Related ICD-10-CM Codes

    22 rows

    ICD-10-CM CodeDescription
    M16.0Bilateral primary osteoarthritis of hip
    M16.11Unilateral primary osteoarthritis, right hip
    M16.12Unilateral primary osteoarthritis, left hip
    M17.0Bilateral primary osteoarthritis of knee
    M17.11Unilateral primary osteoarthritis, right knee
    M17.12Unilateral primary osteoarthritis, left knee
    M17.2Bilateral post-traumatic osteoarthritis of knee
    M17.9Osteoarthritis of knee, unspecified
    M19.011Primary osteoarthritis, right shoulder
    M19.012Primary osteoarthritis, left shoulder

    Showing 1–10 of 22

    Related Payer Policy Updates

    Specialty: Plastic/Reconstructive Surgery1 / 2

    8 rows

    PolicyPayerEffective Date
    Reduction Mammoplasty (Breast Reduction Surgery) for Symptomatic MacromastiaWPS Health Insurance2026-10-01
    Gynecomastia SurgeryCigna2026-08-15
    Panniculectomy (Abdominal skin/fat surgery)moda_health_plan_inc2026-08-13
    Cosmetic and Reconstructive Procedures (for Tennessee Only)UnitedHealthcare2026-08-01
    Breast Reduction Surgery (for Idaho Only)UnitedHealthcare2026-08-01
    Cosmetic and Reconstructive Procedures (for Ohio Only)UnitedHealthcare2026-08-01
    Cosmetic and Reconstructive Procedures (for Kentucky Only)UnitedHealthcare2026-08-01
    Panniculectomy Surgery (for Kansas Only)UnitedHealthcare2026-08-01

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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