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    v1.0.31
    OpenPayerBilling CodesTransnasal EGD and Capsule Endoscopy ProceduresCPT cpt-0654t-transnasal-upper-gi-endoscopy-catheter-placement
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    CPT 0654T: Transnasal Diagnostic Esophagogastroduodenoscopy with Lumen Catheter

    CPT code 0654T describes a diagnostic transnasal endoscopic procedure in which the provider inserts an endoscope through the nose into the esophagus, stomach, and duodenum to inspect the upper gastrointestinal tract and may place a tube or catheter into the GI lumen; service type: diagnostic transnasal esophagogastroduodenoscopy with lumen catheter/tube placement; typical site of service: outpatient endoscopy suite or ambulatory surgical center, or hospital outpatient department.

    For related coverage guidance, see recent payer policy updates: Achalasia and Gastroesophageal Reflux Disease (GERD) - Minimally Invasive Procedures - Medical Policy, Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Gastric Pacing/Gastric Electrical Stimulation (GES).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 55-year-old adult referred to gastroenterology for upper gastrointestinal symptoms such as persistent dyspepsia, chronic heartburn refractory to medical therapy, upper abdominal pain, melena, or unexplained iron-deficiency anemia. After history, physical exam, and noninvasive testing (labs, H. pylori testing, or abdominal imaging as indicated), the provider schedules a diagnostic transnasal esophagogastroduodenoscopy with catheter insertion for luminal assessment and potential sampling. The procedure is performed in an ambulatory surgery center or endoscopy suite; typical site of service is the endoscopy unit or hospital outpatient department. The patient receives topical nasal anesthesia and moderate sedation or monitored anesthesia care depending on comorbidity and institutional protocols. The provider advances a thin endoscope through the nasal passage into the esophagus, stomach, and duodenum to inspect mucosa, obtain biopsies, and, when indicated, insert a catheter or tube into the gastrointestinal lumen for diagnostic contrast injection, pH/impedance catheter placement, or targeted sampling. Recovery and post-procedure observation occur in the same endoscopy unit until discharge criteria are met. Common clinical indications include evaluation of upper GI bleeding, suspected peptic ulcer disease, surveillance of Barrett esophagus, progressive dysphagia, or evaluation of persistent nausea/vomiting.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43235Esophagogastroduodenoscopy, flexible, transoral; diagnostic, with collection of specimen(s) by brushing or washingCommon alternative or complementary diagnostic EGD when transoral approach is used instead of transnasal; cytology sampling
    43239Esophagogastroduodenoscopy, flexible, transoral; with biopsy, single or multiplePerformed when targeted mucosal biopsies are obtained during diagnostic evaluation
    43246Esophagogastroduodenoscopy, flexible, transoral; with transendoscopic stent placementPerformed when luminal stenting becomes necessary after endoscopic assessment
    43267Esophagogastroduodenoscopy, flexible, transoral; with dilation of esophagus, with or without guidePerformed when dilation is required for strictures encountered during endoscopy
    91110Gastrointestinal transit and motility studies; placement of ambulatory pH catheter through previously placed tubeRelated when catheter placement is performed for pH or impedance testing as part of diagnostic workflow

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    2080P0206X
    207L00000X
    146D00000X
    2251S0007X
    246ZG1000X
    224ZL0004X
    207LH0002X

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Achalasia and Gastroesophageal Reflux Disease (GERD) - Minimally Invasive Procedures - Medical PolicyHealth-New-England2027-02-01
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Gastric Pacing/Gastric Electrical Stimulation (GES)Cigna2026-11-15
    Percutaneous Electrical Nerve Field Stimulation for Disorders of Gut-Brain Interactionpremerabluecrossofwashington2026-11-06
    Percutaneous electrical nerve field stimulation for disorders of gut-brain interactionpremerabluecrossofwashington2026-11-06
    Percutaneous Electrical Nerve Field Stimulation for Disorders of Gut-Brain Interactionpremerabluecrossofwashington2026-11-06
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Surgical Site of Care - Colonoscopy and Sigmoidoscopyregence2026-11-01
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15

    Related Codes

    CPT-0651T-MAGNETICALLY-CONTROLLED-CAPSULE-ENDOSCOPY-ESOPHAGUS-STOMACH

    CPT 0651T: Magnetically Steered Capsule Endoscopy of Esophagus and Stomach

    CPT-0652T-TRANSNASAL-UPPER-ENDOSCOPY-DIAGNOSTIC

    CPT 0652T: Nasal Esophagogastroduodenoscopy, Diagnostic

    CPT-0653T-TRANSNASAL-EGD-WITH-BIOPSY

    CPT 0653T: Diagnostic Esophagogastroduodenoscopy with Biopsy

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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