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CPT 0593U: Taq Array Card Urinary Tract Infection PCR Panel

Headline: New PLA CPT code 0593U designates the Taq Array Card Urinary Tract Infection PCR Panel for pathogen and resistance-gene detection

Lead: CPT code 0593U identifies a proprietary real-time PCR urine panel that detects DNA from 28 pathogens and 18 antimicrobial-resistance genes. The code is specific to the Taq Array Card UTI PCR Panel manufactured or performed by SoftCell Laboratories LLC and Doc Lab Inc., enabling standardized billing and clearer tracking of adoption for this single-source laboratory assay.

Why it matters: Molecular assays that rapidly identify pathogens and resistance markers can influence clinical management of urinary tract infections and antibiotic stewardship efforts. A unique PLA code allows payers, providers, and policymakers to monitor utilization of this specific test separately from nonproprietary panels.

Payers covered: The analysis addresses common national payers including Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

What readers will learn: The publication provides benchmarks for coding and billing practices, summaries of payer coverage considerations, clinical context on test purpose and typical use in outpatient and laboratory settings, and practical details about reporting the proprietary assay under CPT code 0593U. Data not available in the input will be noted where applicable.

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Billing Code Overview

CPT code 0593U is a Proprietary Laboratory Analyses (PLA) code that applies only to the specific Taq Array Card Urinary Tract Infection PCR Panel offered by SoftCell Laboratories LLC and Doc Lab Inc. The test detects presence or absence of DNA from 28 bacterial or viral targets and 18 antibiotic-resistance genes using real-time PCR on a urine specimen. Results report each target as present or not present.

Service Type: Molecular diagnostic laboratory test (proprietary PCR panel)

Typical Site of Service: Clinical laboratory using a urine specimen; results reported to ordering clinicians

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Find policies, billing codes, payers, states, and providers

CPT 0593U: Taq Array Card Urinary Tract Infection PCR Panel

Headline: New PLA CPT code 0593U designates the Taq Array Card Urinary Tract Infection PCR Panel for pathogen and resistance-gene detection

Payers covered: The analysis addresses common national payers including Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

Customize your policy alerts

Sign up for cpt 0593U policy alerts

Get alerted when payer policies referencing 0593U are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Billing Code Overview

Service Type: Molecular diagnostic laboratory test (proprietary PCR panel)

Typical Site of Service: Clinical laboratory using a urine specimen; results reported to ordering clinicians

Clinical & Coding Specifications

Clinical Context

A middle‑aged patient presents to an urgent care clinic with dysuria, urinary frequency, and suprapubic discomfort. The clinician performs a focused history and urinalysis; dipstick shows leukocyte esterase and nitrites are negative or equivocal. The clinician collects a clean‑catch urine specimen and orders the Taq Array Card Urinary Tract Infection PCR Panel (0593U) to detect bacterial and viral DNA and antimicrobial resistance genes when rapid, multiplex molecular identification is desired (for complex, recurrent, or complicated urinary tract infection evaluation). The specimen is sent to the performing laboratory (SoftCell Laboratories LLC or Doc Lab Inc.) and processed using real‑time PCR. Results report presence/absence of up to 28 microbial targets and 18 resistance genes, which supports antimicrobial selection and infectious disease consultation when needed. Typical sites of service include outpatient clinics, urgent care centers, emergency departments, and reference laboratories. Turnaround time is generally faster than culture for content-specific identification and resistance gene detection, supporting early targeted therapy decisions and stewardship activities.

Coding Specifications

Modifier	Description	When to Use
`00`	Default indicator (no modifier)	Use when no special billing modifier applies and the claim is submitted without adjustments.
`22`	Increased procedural service	Use when documentation supports substantially greater complexity or work for specimen handling or reporting beyond typical test performance (rare for PLA but applicable if validated by payer).
`52`	Reduced services	Use when the test is partially performed or only a subset of targets processed due to specimen limitations.
`53`	Discontinued procedure	Use if testing was initiated but stopped for clinical or specimen reasons before meaningful results were obtained.
`59`	Distinct procedural service	Use when reporting another distinct service on the same day that is unrelated to the PCR panel (if applicable).
`26`	Professional component	Use when billing only the professional component (interpretation) separate from the technical component (if laboratory splits components and payer requires separation).
`TC`	Technical component	Use when billing only the technical component (performing the test) and another entity bills interpretation.
`90`	Reference (outside) lab	Use when the specimen is sent to an outside reference laboratory and the billing entity is reporting that outside lab service per payer rules.
`96`	Habilitative services	Not typically used for this test but included for payers that require functional service classification (rare).

Taxonomy Code	Specialty	Notes
261QP0800X	Clinical Laboratory	Primary specialty performing and billing the test in a reference lab setting.
207Q00000X	Emergency Medicine	Ordering specialty in ED when rapid molecular UTI diagnostics guide ED management.
261QM0500X	Pathology (Molecular)	Specialty responsible for molecular diagnostic oversight and result validation.
207L00000X	Family Medicine	Common outpatient ordering specialty for patients with suspected UTI.
207R00000X	Internal Medicine	Common ordering specialty for primary care or inpatient medicine managing UTIs.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
Data not available in the input.	Data not available in the input.	Data not available in the input.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`81002`	Urinalysis, by dipstick or tablet reagent; non-automated, without microscopy	Often performed at point of care prior to ordering the PCR panel to assess pyuria or hematuria.
`81025`	Urine pregnancy test, by visual color comparison methods	Performed in women of childbearing potential before initiating certain antimicrobial therapies or imaging.
`87086`	Culture, bacterial; quantitative, urine	Traditional urine culture performed alongside or after PCR to obtain isolates for full susceptibility testing when indicated.
`87471`	Infectious agent detection by nucleic acid (DNA or RNA); Chlamydia trachomatis, amplified probe technique	Example of other NAATs that may be ordered concurrently for urogenital infection workup in symptomatic patients.
`86328`	Antibody; microorganism(s) for infectious agent detection by enzyme immunoassay	Ancillary serologic testing that may be ordered in complex cases; not routine for acute uncomplicated UTI.

CPT 0001U: PreciseType HEA Multiplex Erythrocyte Antigen Assay

CPT-0002U-POLYPDX-URINE-METABOLOMIC-ASSAY-ADENOMATOUS-POLYP-RISK

CPT 0002U: Urine Metabolomic Polyp Risk Assay (PolypDX™)

CPT-0003U-OVAR-A-NEXT-GENERATION-OVARIAN-CANCER-RISK-ASSAY

CPT 0003U: Overa™ (OVA1 Next Generation) Ovarian Cancer Risk Assay

CPT-0005U-PROSTATE-EXOSOMEDX-INTELLISCORE-GENE-EXPRESSION-URINE-TEST

CPT 0005U: ExosomeDx Prostate (IntelliScore) Urine Gene Expression Risk Test

CPT-0007U-TOXPROTECT-URINE-DRUG-SCREEN-WITH-DNA-AUTHENTICATION

CPT 0007U: ToxProtect Urine Drug Screen with DNA Authentication

CPT-0008U-H-PYLORI-ANTIBIOTIC-RESISTANCE-SEQUENCING-PANEL

CPT 0008U: H. pylori Antibiotic Resistance Panel, Gene Sequence Analysis

CPT-0009U-DEPARRAY-HER2-FISH-TUMOR-CELL-ISOLATION

CPT 0009U: DEPArray HER2 Tumor‑Cell Isolation with FISH Analysis

CPT-0010U-BACTERIAL-TYPING-WHOLE-GENOME-SEQUENCING-MAYO-CLINIC

CPT 0010U: Bacterial Typing by Whole Genome Sequencing, Mayo Clinic

CPT-0011U-CORDANT-CORE-ALGORITHMIC-ORAL-FLUID-DRUG-TEST

CPT 0011U: Cordant CORE™ Oral Fluid Drug Test with Algorithmic Steady‑State Comparison

CPT-0016U-BCR-ABL1-MAJOR-MINOR-FUSION-TRANSCRIPT-TESTING

CPT 0016U: BCR–ABL1 Major and Minor Breakpoint Fusion Transcript Testing

Showing 1–10 of 536

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Coding Specifications

Modifier	Description	When to Use
`00`	Default indicator (no modifier)	Use when no special billing modifier applies and the claim is submitted without adjustments.
`22`	Increased procedural service	Use when documentation supports substantially greater complexity or work for specimen handling or reporting beyond typical test performance (rare for PLA but applicable if validated by payer).
`52`	Reduced services	Use when the test is partially performed or only a subset of targets processed due to specimen limitations.
`53`	Discontinued procedure	Use if testing was initiated but stopped for clinical or specimen reasons before meaningful results were obtained.
`59`	Distinct procedural service	Use when reporting another distinct service on the same day that is unrelated to the PCR panel (if applicable).
`26`	Professional component	Use when billing only the professional component (interpretation) separate from the technical component (if laboratory splits components and payer requires separation).
`TC`	Technical component	Use when billing only the technical component (performing the test) and another entity bills interpretation.
`90`	Reference (outside) lab	Use when the specimen is sent to an outside reference laboratory and the billing entity is reporting that outside lab service per payer rules.
`96`	Habilitative services	Not typically used for this test but included for payers that require functional service classification (rare).

Taxonomy Code	Specialty	Notes
261QP0800X	Clinical Laboratory	Primary specialty performing and billing the test in a reference lab setting.
207Q00000X	Emergency Medicine	Ordering specialty in ED when rapid molecular UTI diagnostics guide ED management.
261QM0500X	Pathology (Molecular)	Specialty responsible for molecular diagnostic oversight and result validation.
207L00000X	Family Medicine	Common outpatient ordering specialty for patients with suspected UTI.
207R00000X	Internal Medicine	Common ordering specialty for primary care or inpatient medicine managing UTIs.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
Data not available in the input.	Data not available in the input.	Data not available in the input.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`81002`	Urinalysis, by dipstick or tablet reagent; non-automated, without microscopy	Often performed at point of care prior to ordering the PCR panel to assess pyuria or hematuria.
`81025`	Urine pregnancy test, by visual color comparison methods	Performed in women of childbearing potential before initiating certain antimicrobial therapies or imaging.
`87086`	Culture, bacterial; quantitative, urine	Traditional urine culture performed alongside or after PCR to obtain isolates for full susceptibility testing when indicated.
`87471`	Infectious agent detection by nucleic acid (DNA or RNA); Chlamydia trachomatis, amplified probe technique	Example of other NAATs that may be ordered concurrently for urogenital infection workup in symptomatic patients.
`86328`	Antibody; microorganism(s) for infectious agent detection by enzyme immunoassay	Ancillary serologic testing that may be ordered in complex cases; not routine for acute uncomplicated UTI.

CPT 0001U: PreciseType HEA Multiplex Erythrocyte Antigen Assay

CPT-0002U-POLYPDX-URINE-METABOLOMIC-ASSAY-ADENOMATOUS-POLYP-RISK

CPT 0002U: Urine Metabolomic Polyp Risk Assay (PolypDX™)

CPT-0003U-OVAR-A-NEXT-GENERATION-OVARIAN-CANCER-RISK-ASSAY

CPT 0003U: Overa™ (OVA1 Next Generation) Ovarian Cancer Risk Assay

CPT-0005U-PROSTATE-EXOSOMEDX-INTELLISCORE-GENE-EXPRESSION-URINE-TEST

CPT 0005U: ExosomeDx Prostate (IntelliScore) Urine Gene Expression Risk Test

CPT-0007U-TOXPROTECT-URINE-DRUG-SCREEN-WITH-DNA-AUTHENTICATION

CPT 0007U: ToxProtect Urine Drug Screen with DNA Authentication

CPT-0008U-H-PYLORI-ANTIBIOTIC-RESISTANCE-SEQUENCING-PANEL

CPT 0008U: H. pylori Antibiotic Resistance Panel, Gene Sequence Analysis

CPT-0009U-DEPARRAY-HER2-FISH-TUMOR-CELL-ISOLATION

CPT 0009U: DEPArray HER2 Tumor‑Cell Isolation with FISH Analysis

CPT-0010U-BACTERIAL-TYPING-WHOLE-GENOME-SEQUENCING-MAYO-CLINIC

CPT 0010U: Bacterial Typing by Whole Genome Sequencing, Mayo Clinic

CPT-0011U-CORDANT-CORE-ALGORITHMIC-ORAL-FLUID-DRUG-TEST

CPT 0011U: Cordant CORE™ Oral Fluid Drug Test with Algorithmic Steady‑State Comparison

CPT-0016U-BCR-ABL1-MAJOR-MINOR-FUSION-TRANSCRIPT-TESTING

CPT 0016U: BCR–ABL1 Major and Minor Breakpoint Fusion Transcript Testing

Showing 1–10 of 536

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

CPT 0593U: Taq Array Card Urinary Tract Infection PCR Panel

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Billing Code Overview

OpenPayer

CPT 0593U: Taq Array Card Urinary Tract Infection PCR Panel

Sign up for cpt 0593U policy alerts

Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

CPT 0593U: Taq Array Card Urinary Tract Infection PCR Panel

Sign up for cpt 0593U policy alerts

Billing Code Overview

CPT 0593U: Taq Array Card Urinary Tract Infection PCR Panel

Sign up for cpt 0593U policy alerts

Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

What does CPT 0593U represent and which laboratories perform it?

Where is the test typically ordered and processed, and what specimen is used?

Which modifiers may be used with 0593U and when are they applicable?

What other tests are commonly ordered alongside or prior to the Taq Array Card UTI PCR Panel?

Which payers are referenced and does the page provide reimbursement rates or coverage specifics?

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

What does CPT 0593U represent and which laboratories perform it?

Where is the test typically ordered and processed, and what specimen is used?

Which modifiers may be used with 0593U and when are they applicable?

What other tests are commonly ordered alongside or prior to the Taq Array Card UTI PCR Panel?

Which payers are referenced and does the page provide reimbursement rates or coverage specifics?

References