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    OpenPayerBilling CodesPercutaneous Cryoablation ProceduresCPT cpt-0440t-upper-extremity-peripheral-nerve-cryoablation
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    CPT 0440T: Cryoablation of Distal Peripheral Nerve, Upper Extremity

    CPT code 0440T describes cryoablation, the application of freezing temperature to destroy a distal/peripheral nerve near the end of the upper extremity for treatment of complex regional pain syndrome or other neuropathy; this procedure is a peripheral nerve cryoablation service typically performed in an outpatient or ambulatory surgery setting or specialized pain clinic and involves image-guided delivery of cryotherapy to a distal nerve to provide targeted neurolysis and pain relief.

    For related coverage guidance, see recent payer policy updates: Intraosseous Basivertebral Nerve Ablation for Child Health Plus (CHP) and Essential Plan (EP) Members, Acupuncture Services Payment Policy, Drug Testing in Pain Management and Substance Use Disorder.

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    Clinical & Coding Specifications

    Clinical Context

    A 45-year-old right-hand–dominant patient presents with persistent, severe neuropathic pain of the distal forearm and hand following a wrist fracture and subsequent complex regional pain syndrome (CRPS) Type II. Conservative therapy including physical therapy, oral neuropathic agents, and corticosteroid injection provided inadequate relief. The pain interferes with activities of daily living and sleep and localizes to branches of the superficial radial nerve and digital nerves. The interventional pain specialist evaluates the patient, documents a focused history and targeted sensory and motor exam, and confirms the painful peripheral nerve distribution with diagnostic local anesthetic block(s). After informed consent, the provider performs percutaneous cryoablation of the distal/peripheral nerve under sterile technique using imaging as needed, monitors vital signs, and provides post-procedure instructions and follow-up planning.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    64633Chemodenervation of peripheral nerve(s) (e.g., for spasticity)May be part of diagnostic or therapeutic regimen for peripheral neuropathic pain; alternative neuromodulatory intervention.
    20526Injection, therapeutic, carpal tunnel area, percutaneous (including ultrasound guidance)Diagnostic or therapeutic local injections to identify symptomatic nerve(s) or provide temporary relief before cryoablation.
    64450Injection, anesthetic agent; other peripheral nerve or branch (e.g., stellate ganglion block is 64490 for sympathetic chain)Diagnostic nerve block to confirm nerve target prior to proceeding with cryoablation.
    99024Postoperative follow-up visit, related to surgical procedure during global periodUsed to bill postoperative visits associated with cryoablation when applicable per payer rules.
    95970Electronic analysis of implanted neurostimulator pulse generator systemRelevant when patients have neuromodulation devices as alternative or adjunctive therapy; represents related device management.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RH0000X
    2084P0800X
    2084N0400X
    208D00000X
    163W00000X
    207WX0120X
    133VN1401X
    2084N0600X

    Related ICD-10-CM Codes

    21 rows

    ICD-10-CM CodeDescription
    G56.01Carpal tunnel syndrome, right upper limb
    G56.02Carpal tunnel syndrome, left upper limb
    G56.21Lesion of ulnar nerve, right upper limb
    G57.01Lesion of sciatic nerve, right lower limb
    G57.02Lesion of sciatic nerve, left lower limb
    G58.0Intercostal neuropathy
    G58.8Other specified mononeuropathies
    G60.9Hereditary and idiopathic neuropathy, unspecified
    G62.0Drug-induced polyneuropathy
    G89.0Central pain syndrome

    Showing 1–10 of 21

    Related Payer Policy Updates

    Specialty: Pain Management1 / 3

    10 rows

    PolicyPayerEffective Date
    Intraosseous Basivertebral Nerve Ablation for Child Health Plus (CHP) and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Acupuncture Services Payment Policyfallon_community_health_plan_inc2026-12-01
    Drug Testing in Pain Management and Substance Use Disorderbcbsvermont2026-11-01
    Lysis of Epidural Adhesionsexcellus_health_plan_inc2026-10-15
    Intradiscal Proceduresexcellus_health_plan_inc2026-10-15
    Facet Joint Injections/ Medial Branch Blocksuniverahealthcare2026-10-15
    Radiofrequency Facet and Sacroiliac Joint Ablation/ Denervationuniverahealthcare2026-10-15
    Epidural Steroid Injections / Selective Nerve Root Block (SNRB)univerahealthcare2026-10-15
    Lysis of Epidural Adhesions (Epidural Adhesiolysis)univerahealthcare2026-10-15
    Prolotherapyuniverahealthcare2026-10-15

    Related Codes

    CPT-0441T-DISTAL-LOWER-EXTREMITY-NERVE-CRYOABLATION

    CPT 0441T: Cryoablation of Distal Lower Extremity Peripheral Nerve

    CPT-0442T-CRYOABLATION-NERVE-PLEXUS-TRUNK-PUDENDUM

    CPT 0442T: Cryoablation of Trunk or Pudendal Nerve Plexus

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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