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    v1.0.30
    OpenPayerBilling CodesHigh Dose Rate Electronic Brachytherapy ProceduresCPT cpt-0395t-intracavitary-interstitial-brachytherapy-dosimetry
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    CPT 0395T: Brachytherapy Catheter Placement, Interstitial or Intracavitary

    CPT code 0395T describes placement of a catheter for interstitial or intracavitary brachytherapy, where a high-energy radioactive source is loaded into catheters placed within the tumor or body cavity to deliver targeted radiation; the service includes dosimetry (dose calculation) when performed and is reported for each fraction or portion of the planned total dose. This procedure is a brachytherapy service typically performed in an ambulatory surgery center, hospital outpatient department, or radiation oncology clinic and involves radiation oncology planning, catheter placement, and delivery of a radioactive source for local tumor treatment.

    For related coverage guidance, see recent payer policy updates: Mohs Micrographic Surgery, Mohs Micrographic Surgery, Mohs Micrographic Surgery.

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    Clinical & Coding Specifications

    Clinical Context

    A 64-year-old patient with a recently diagnosed localized cervical carcinoma is scheduled for intracavitary high-dose-rate (HDR) brachytherapy following external beam radiation therapy. The patient arrives to the radiation oncology suite in a monitored setting. Under conscious sedation or general anesthesia, the radiation oncologist inserts a gynecologic applicator and places interstitial catheters into tumor tissue as indicated. Dosimetry calculations (treatment planning) are performed prior to loading the radioactive source into the catheters. Each treatment fraction is delivered with source loading and dwell-time control; this service is reported per fraction using 0395T. The clinical workflow includes pre-procedure consent and imaging, applicator/catheter placement, treatment planning/dosimetry, source loading and delivery, and post-treatment monitoring and documentation. Typical sites of service are an outpatient radiation oncology department, ambulatory surgery center, or hospital-based procedure room depending on anesthesia needs and patient acuity.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    0395TInsertion of interstitial and/or intracavitary catheters for brachytherapy; per fraction, includes dosimetry when performedPrimary CPT for each delivered fraction of HDR interstitial/intracavitary brachytherapy.
    77301Brachytherapy dosimetry calculation, each source arrangement, simpleOften performed during treatment planning to calculate dose distributions prior to source loading.
    77295High dose rate brachytherapy; delivery, per fractionUsed by some providers/facilities to report HDR brachytherapy delivery when applicable in documentation workflows.
    55874Transperineal placement of needles/implants for permanent prostate brachytherapy; placement of radioactive sourcesRelated implant-placement technique in urologic brachytherapy workflows (different anatomic site).
    57455Colposcopy with cervical biopsy (separate procedure code example for pre-procedure diagnostic workup)Diagnostic procedures that may be part of the pre-brachytherapy evaluation in gynecologic cases.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208D00000X
    207RC0000X
    101200000X
    163WU0100X
    2081P2900X
    2084H0002X
    2279E0002X
    207RG0100X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    C16.9Malignant neoplasm of stomach, unspecified
    C18.9Malignant neoplasm of colon, unspecified
    C22.0Liver cell carcinoma
    C25.9Malignant neoplasm of pancreas, unspecified
    C31.9Malignant neoplasm of accessory sinus, unspecified
    C32.9Malignant neoplasm of larynx, unspecified
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    C41.9Malignant neoplasm of bone and articular cartilage, unspecified
    C43.9Malignant melanoma of skin, unspecified
    C44.511Basal cell carcinoma of skin of breast

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    10 rows

    PolicyPayerEffective Date
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    FilsuvezCigna2026-11-01
    Destruction of Pre-Malignant Skin LesionsAnthem2026-10-01
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Treatment of Capillary Malformations (Port Wine Stains)universityofutahhealthplans2026-09-28
    AnzupgoCigna2026-09-15
    Hyperhidrosispriority_health_medicare2026-09-01
    Zevaskyn Coverage for Recessive Dystrophic Epidermolysis BullosaCigna2026-09-01

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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