Clinical Context
A symptomatic patient with unexplained mucocutaneous bleeding, easy bruising, heavy menstrual bleeding, recurrent epistaxis, or a family history of inherited bleeding disorders is evaluated. A hematologist orders the Versiti™ Comprehensive Bleeding Disorder Panel (0272U) to identify pathogenic variants in 60 genes associated with platelet function and coagulation, and to detect PLAU gene duplication/deletion. Specimen types include peripheral blood, buccal swab, or amniotic fluid. The clinical workflow: initial clinical assessment and coagulation screening tests (CBC, PT/INR, aPTT, fibrinogen, platelet function assays) are performed; if results are inconclusive or genetic confirmation/ familial risk assessment is needed, the provider obtains informed consent for genetic testing, collects the specimen, and sends it to Versiti™ Diagnostic Laboratories. Results are reviewed by the ordering clinician and incorporated into diagnosis, counseling, family testing decisions, and treatment planning (including periprocedural management and targeted therapies). Typical site of service is an outpatient clinic, hospital outpatient laboratory, or specialized genetic testing laboratory facility. Common payors include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, BUCA plans, and Medicare.
Related CPT Codes
| CPT Code | Description | Relationship to This Procedure |
|---|
82948 | Glucose; blood, reagent strip | Data not available in the input. |
36415 | Collection of venous blood by venipuncture | Commonly performed prior to sending specimen for the 0272U genetic test; documents specimen collection. |
81479 | Unlisted molecular pathology procedure | May be used historically for novel or complex molecular tests prior to PLA assignment; replaced by specific PLA 0272U. |
88381 | Immunohistochemistry or special stains, interpretation | Data not available in the input. |
81225 | CFTR (cystic fibrosis transmembrane conductance regulator) gene analysis | Data not available in the input. |
Note: If a related code list was not provided in the input, clinical practice commonly pairs 0272U with specimen collection codes such as 36415 and with other molecular or genetic counseling services; however, only codes listed above are included per input constraints.