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    v1.0.28
    OpenPayerBilling CodesAnesthesia for Other ProceduresCPT cpt-01991-anesthesia-for-nerve-block-injection-non-prone
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    CPT 01991: Anesthesia for Nerve Block or Injection (Nonprone)

    Commercial payers pay $86 on average nationally for this procedure.

    CPT code 01991 describes anesthesia services provided when an anesthesia clinician manages the anesthetic care for a patient undergoing a diagnostic or therapeutic peripheral nerve block or injection performed by another provider; the service typically involves moderate or regional anesthetic techniques for procedures performed with the patient supine or in a nonprone position and is commonly delivered in an outpatient procedure suite, ambulatory surgery center, or hospital procedure room.

    For related coverage guidance, see recent payer policy updates: Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders, Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders, Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders.

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    National Reimbursement Benchmarks

    For CPT 01991 the average commercial benchmark (BUCA) centers near $86.00, with individual payers varying around that midpoint. Blue Cross Blue Shield (BCBS) and UnitedHealth Group sit below BUCA on mean rates ($82.20 and $68.30 respectively), while Aetna and Cigna are above at $96.00 and $105.00. Cigna and Aetna present higher top-end ceilings ($176.80 and $312.40) versus UnitedHealth Group’s lower cap ($122.70), indicating differences in upper-tail settlement for complex cases.

    Examining dispersion using the interquartile range (P75–P25) highlights who is tightest and widest: UnitedHealth Group is the tightest with a $31.40 IQR ($81.40–$52.00), BCBS follows with a $29.5 IQR ($104.70–$58.20). Aetna shows the widest IQR at $83.5 ($128.00–$45.00), with Cigna also relatively wide at $61.0 ($139.00–$73.10). BUCA’s IQR is $34.6 ($110.40–$57.40), placing it near the middle of the dispersion spectrum.

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    National Payer Mean Reimbursement Rates

    State Reimbursement Rates

    State: Alaska1 / 51

    Rate by payer

    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient with chronic low back pain (M54.5) and radicular symptoms is scheduled for a diagnostic lumbar transforaminal epidural steroid injection performed by an interventional pain physician. An anesthesiologist is asked to provide monitored anesthesia care (MAC) for patient comfort and sedation during the injection. The anesthesiologist documents pre-procedure evaluation, titrates sedation intra-procedure, manages airway and hemodynamics, and provides immediate post-procedure recovery. The procedure is performed with the patient in a supine or lateral position (not prone or flat), and the anesthesiologist does not perform the injection itself. Typical workflow: pre-op assessment in procedure suite, IV placement, sedation onset, continuous monitoring (ECG, pulse oximetry, blood pressure), communication with the proceduralist during needle placement and contrast/therapeutic injection, management of sedation-related events if they arise, transfer to PACU for recovery and discharge instructions. Payors commonly involved include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, BUCA, and Medicare.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    64450Injection, anesthetic agent; other peripheral nerve or branchMay be the diagnostic or therapeutic injection performed by the proceduralist while the anesthesiologist provides MAC or anesthesia services billed with .

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207LP2900XPain Medicine (Anesthesiology) PhysicianAn anesthesiologist who provides a high level of care, either as a primary physician or consultant, for patients experiencing problems with acute, chr…
    207RA0401XAddiction Medicine (Internal Medicine) PhysicianAn internist doctor of osteopathy that specializes in the treatment of addiction disorders. A doctor of osteopathy that is board eligible/certified b…
    133VN1005XRenal Nutrition Registered DietitianAn individual who is a Board Certified Specialist in Renal Nutrition and works directly with adult and/or pediatric patients with acute kidney injury,…
    2278P3800XPalliative/Hospice Certified Respiratory TherapistA coordinated plan of care to help dying patients and their families handle the burden of terminal care. Effective secretion management and relief of…
    146L00000XParamedicAn EMT, Paramedic is an individual trained and certified to perform advanced life support (ALS) in medical emergencies based on individual state board…
    261QV0200XVA Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center
    163WC1400XCollege Health Registered NurseNursing Service Providers · Registered Nurse

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    G56.01Carpal tunnel syndrome, right upper limb
    G58.0Intercostal neuropathy
    G89.18Other acute postprocedural pain
    G89.29Other chronic pain
    M19.071Primary osteoarthritis, right ankle and foot
    M19.072Primary osteoarthritis, left ankle and foot
    M25.561Pain in right knee
    M25.562Pain in left knee
    M47.26Other spondylosis with radiculopathy, lumbar region
    M47.816Spondylosis without myelopathy or radiculopathy, lumbar region

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 4

    7 rows

    PolicyPayerEffective Date
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-01990-ANESTHESIOLOGY-ORGAN-PROCUREMENT-PHYSIOLOGIC-SUPPORT

    CPT 01990: Anesthesiology Physiological Support for Brain-Dead Organ Donor

    CPT-01992-ANESTHESIA-FOR-NERVE-BLOCK-PRONE-SUPINE

    CPT 01992: Anesthesia for Nerve Block or Injection, Prone or Supine

    CPT-01996-ANESTHESIA-MANAGEMENT-CONTINUOUS-NEURAXIAL-DRUG-ADMINISTRATION

    CPT 01996: Anesthesia for Continuous Epidural or Subarachnoid Drug Administration

    CPT-01999-UNLISTED-ANESTHESIA-PROCEDURE

    CPT 01999: Anesthesia Unlisted Procedure

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    01991
    20610Arthrocentesis, aspiration and/or injection into a major joint or bursaJoint injections performed by proceduralist for which anesthetic support per 01991 may be provided if sedation/monitoring is required.
    62322Injection(s), of diagnostic or therapeutic substance(s) (e.g., anesthetic, antispasmodic, opioid, steroid)Epidural or intrathecal injections performed by proceduralist; anesthesiologist bills 01991 when providing anesthesia for these injections.
    64483Injection(s), anesthetic agent and/or steroid, transforaminal epidural; lumbar or sacral, single levelA common proceduralist code for transforaminal epidural steroid injection during which anesthesia services described by 01991 may be furnished for patient comfort.