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    v1.0.30
    OpenPayerBilling CodesVarious Services - Category III CodesCPT cpt-0108t-cold-sensation-pain-threshold-testing
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    CPT 0108T: Cold Sensation and Pain Threshold Testing

    CPT code 0108T documents a provider-performed quantitative sensory test that determines cold sensation and pain thresholds by stimulating the skin of an extremity and comparing findings to normal values; this diagnostic sensory assessment is performed to evaluate cooling sensory function and small nerve ending damage and is typically performed as an outpatient diagnostic procedure in a clinic or neurology/physiatry testing lab.

    For related coverage guidance, see recent payer policy updates: Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation.

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    Clinical & Coding Specifications

    Clinical Context

    A 54-year-old patient with a history of chemotherapy-induced peripheral neuropathy presents with persistent numbness and burning pain in the distal lower extremities. The referring neurologist orders quantitative sensory testing to evaluate small-fiber sensory function. In the outpatient neurodiagnostic laboratory, a trained clinician explains the 0108T test purpose and obtains informed consent. The patient is positioned comfortably with the lower extremity exposed. The clinician applies calibrated cold stimuli to standardized sites on the foot and lower leg while recording the temperature thresholds at which the patient first perceives cold and the temperature at which the sensation becomes painful. Results are compared to age- and sex-matched normative values and documented in the report. The findings help confirm small-fiber neuropathy, guide further diagnostic evaluation (for example, skin biopsy or autonomic testing), and inform management decisions such as medication selection and referral to pain management or physical therapy.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    95900Motor nerve conduction, amplitude and latency/velocity study; per limbPerformed when large-fiber neuropathy is suspected alongside small-fiber testing to provide a comprehensive electrodiagnostic evaluation.
    95907Sensory nerve conduction, amplitude and latency/velocity study; per limbComplements cold perception threshold testing by objectively assessing large-fiber sensory conduction.
    95913Needle electromyography (EMG); two to three muscle(s)Used to evaluate for concurrent motor neuropathy or radiculopathy when clinical exam suggests mixed-fiber involvement.
    0306TQuantitative sudomotor axon reflex test (QSART)Assesses autonomic small-fiber function and is often ordered with cold threshold testing to evaluate small-fiber neuropathy comprehensively.
    0488TQuantitative sensory testing, temperature and vibration thresholdsRelated specialized sensory testing; may be billed when a more extensive battery of quantitative sensory tests is performed.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    2084N0400X
    207L00000X
    207K00000X
    363LF0000X
    171100000X
    3336C0003X
    2086S0105X

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure - Medical PolicyHealth-New-England2027-02-01
    Transcatheter Mitral Valve Repair Medical PolicyHealth-New-England2027-02-01
    Cardiac Electrophysiological (EP) Studies and Cardiac Ablation of Abnormal Electrical RhythmsCigna2027-01-15
    Biomarkers for Myocardial Infarction and Chronic Heart Failure Reimbursement PolicyHealthfirst2026-11-01
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2026-11-01
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2026-11-01
    Cardiology - TryvioCigna2026-11-01

    Related Codes

    CPT-0054T-ORTHOPEDIC-IMPLANT-NAVIGATION-FLUOROSCOPY

    CPT 0054T: Surgical Navigation for Orthopedic Implant Positioning

    CPT-0055T-CT-MRI-GUIDED-ORTHOPEDIC-IMPLANT-NAVIGATION

    CPT 0055T: Image-Guided Orthopedic Implant Navigation

    CPT-0071T-MRGFUS-UTERINE-FIBROID-ABLATION

    CPT 0071T: MRI‑guided Focused Ultrasound Ablation of Uterine Fibroids ≤200 cc

    CPT-0072T-MRGFUS-ABLATION-UTERINE-FIBROIDS-200CC-PLUS

    CPT 0072T: MRgFUS Ablation of Uterine Leiomyomata ≥200 cc

    CPT-0075T-EXTRACRANIAL-VERTEBRAL-ARTERY-STENT-PLACEMENT

    CPT 0075T: Extracranial Vertebral Artery Stent Placement

    CPT-0076T-EXTRACRANIAL-VERTEBRAL-ARTERY-ADDITIONAL-STENT-PLACEMENT

    CPT 0076T: Extracranial Vertebral Artery Additional Stent Placement

    CPT-0095T-CERVICAL-ARTIFICIAL-DISC-REMOVAL-ADD-ON

    CPT 0095T: Removal of Additional Cervical Artificial Disc

    CPT-0098T-CERVICAL-ARTIFICIAL-DISC-REVISION-REPLACEMENT-ADD-ON

    CPT 0098T: Cervical Artificial Disc Revision and Replacement (Add-on)

    CPT-0100T-RETINAL-PROSTHESIS-IMPLANTATION-ARTIFICIAL-RETINA

    CPT 0100T: Epiretinal Prosthesis (Retinal Implant) Attachment

    CPT-0101T-SHOCK-WAVE-THERAPY-MUSCULOSKELETAL-PAIN

    CPT 0101T: Extracorporeal Shock Wave Therapy, Other Site

    Showing 1–10 of 42

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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